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Name : lysS (CGSHiEE_05980) Accession : YP_001290934.1 Strain : Haemophilus influenzae PittEE Genome accession: NC_009566 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 1188623 - 1190131 bp Length : 1509 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGTCAGAACAAGAAGTTAAAGAATTAGATCTCAATGGCGAAATGCTCGTTCGTCGTGAAAAATTATCCGCATTACGTGC AAAAGGTAATGCCTTTCCAAACAAGTTTCGTCGTGATGCTCTCGCACAAGATTTACACAATCAATATGATTCAGAAGACG GGGAAATCTTAAAAGAGAAAGGCGTTGAAGTACAGGTTGCTGGTCGTATTATGACTCGTCGTGCAATGGGTAAAGCAACT TTTATCACTATTCAAGATATGAGCGGTAAAATCCAGCTTTACGTTGCACGCGATAATTTGCCTGAAGGTGTTTATGCTGA AGATGTAGGTAACTGGGATTTAGGCGATATCATTGGAGTGAAAGGTACACTTTTCAAAACTAAAACCAATGAATTAACCA TCAAAACAACTGAAGTTCAACTTTTAACCAAAGCACTTCGTCCATTACCAGACAAATTCCATGGTTTAACCGACCAAGAA GTTCGTTATCGCCAACGTTATTTAGATTTAATTTCTAACGAAGAATCTCGCCGCACTTTTATTATTCGTTCTAAAGTTGT CGCGGGGATTCGTGAATATTTCATTTCTAAAGGCTTTATGGAAGTGGAAACGCCAATGTTACAAGTAATTCCAGGCGGTG CATCTGCACGTCCTTTCGTGACTCATCATAATGCATTAGATGTGGATATGTATTTGCGTATCGCACCTGAACTTTATTTA AAACGCTTAGTCGTTGGTGGGTTTGAACGAGTATTTGAATTAAACCGTAACTTCCGTAATGAAGGGGTTTCTGTTCGTCA TAATCCAGAATTTACTATGCTTGAATACTATCAAGCCTATGCAGATTACCACGATTTAATGGATAACACCGAAGAACTTC TTCGTAAATTAGCGATTGATATTCTTGGTACAACCATTGTGAAATACGGTGATTTAGAATTTGACTTCGGCAAACCATTT GAGCGTATTACATTACACGATGCAACGGTTAAATATGGTGCTGACAAAGGTATCGTAAAAGAAGATTTATATGACTTTGA TCGTGCAAAAGCCACGGCAGAACGCTTAGGTATTGAAGTACAAAAATCTTGGGGTTTAGGCAGCATTGTCAATGCAATTT TTGAAGAAGTAGCTGAACATCATTTAATTCAACCAACCTTCTTAATGGCTCACCCTGCGGAAATTTCGCCACTTGCACGT CGTAATGATGAAAACCCTGAAGTGACTGACCGTTTTGAACTATTTATCGGTGGCCGTGAAATCGGTAATGGTTTCTCAGA ATTAAATGATGCAGAAGATCAAAATGAACGTTTTGATGCACAGGTTGCTGCGAAAGAAGCGGGCGATGATGAAGCGATGT TTAAAGATGAAGACTTTGTTGTTGCACTAGAACACGGCTTACCTCCAACAGCTGGGGAAGGTTTAGGTATCGACCGCTTG GCGATGCTTTATGCAAATGCACCATCCATTCGTGATGTGATCTTGTTCCCTGCAATGCGTCAGAAATAA Protein sequence : MSEQEVKELDLNGEMLVRREKLSALRAKGNAFPNKFRRDALAQDLHNQYDSEDGEILKEKGVEVQVAGRIMTRRAMGKAT FITIQDMSGKIQLYVARDNLPEGVYAEDVGNWDLGDIIGVKGTLFKTKTNELTIKTTEVQLLTKALRPLPDKFHGLTDQE VRYRQRYLDLISNEESRRTFIIRSKVVAGIREYFISKGFMEVETPMLQVIPGGASARPFVTHHNALDVDMYLRIAPELYL KRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMLEYYQAYADYHDLMDNTEELLRKLAIDILGTTIVKYGDLEFDFGKPF ERITLHDATVKYGADKGIVKEDLYDFDRAKATAERLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLMAHPAEISPLAR RNDENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEAMFKDEDFVVALEHGLPPTAGEGLGIDRL AMLYANAPSIRDVILFPAMRQK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 1e-152 | 63 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 6e-89 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_001290934.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 7e-153 | 63 |
