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Name : CGSHiEE_05445 (CGSHiEE_05445) Accession : YP_001290848.1 Strain : Haemophilus influenzae PittEE Genome accession: NC_009566 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 1089578 - 1091014 bp Length : 1437 bp Strand : + Note : catalyzes the formation of phosphoenolpyruvate from pyruvate DNA sequence : ATGTCTAGAAGACTAAGAAGAACGAAGATTGTATGTACTATGGGCCCATCAACTGACCGTGATAACAATCTTGAAAAAAT TATCGCAGCGGGCGCAAACGTAGTTCGTATGAACTTCTCTCACGGTACACCTGATGACCATATCGGACGTGCTGAACGTG TACGTTCTATTGCGAAAAAATTAGGTAAAACCGTGGCAATCTTAGGTGATTTACAAGGTCCTAAAATTCGTGTTTCTACT TTTAAAGACGGTAAAATTTTCTTAAACGTTGGCGATAAATTCATTCTTGATGCAGAGTTACCAAAAGGCGAAGGCACTCA AGAATCCGTTGGTTTAGACTATAAAACGCTTCCTCAAGATGTTGTGCCTGGCGATATTCTTTTATTAGATGATGGCCGTG TTCAATTAAAAGTATTATCAACTGATGGTGCAAAAGTTTTCACTGAAGTTACTGTTGGTGGTCCATTATCAAATAATAAA GGTATCAATAAATTAGGTGGCGGTTTATCTGCGGATGCCCTAACAGAAAAAGATAAAGCCGACATTATTACCGCTGCACG CATTGGTGTTGATTTCTTAGCCGTTTCTTTCCCTCGTTCAAGTGCAGATTTAAATTATGCACGTGAACTTGCTCAACAAG CAGGTTTAAATGCAAAAATCGTTGCTAAAGTTGAACGTGCAGAAACCGTTGCTAATGATGAAGCCATGGACGATATTATT TTAGCATCTGATGTAATTATGGTTGCTCGTGGTGACTTAGGCGTAGAAATCGGCGATCCTGAATTAGTCGGTGTACAGAA AAAATTAATTCGTCGTTCACGTCAATTAAATCGTGCTGTAATTACAGCGACTCAAATGATGGAATCAATGATTAGTAACC CAATGCCAACGCGTGCTGAAGTAATGGACGTTGCAAACGCAGTATTAGATGGAACTGATGCAGTTATGCTTTCTGCAGAA ACAGCAGCAGGTCAATATCCTTCTGAAACAGTGGCAGCAATGGCTAGCGTATGTTTAGGTGCAGAAAAAATGCCAAGCAT TAACGTTTCTCGTCACCGTATGGATAAAGAATTTGAAACCATTGAAGAATCTGTTGCGATGTCTGCAATGTATGCAGCAA ACCACATGAAAGGTGTAGCGGCAATCGTCACTTTAACTAGCACAGGCCGTACTCCATTATTAATGTCACGCATTAGCTCT GGCTTACCAATCTTTGCTTTATCTCGTAATCAAGAAACCCTAAACCTTTGTGCACTATACCGCGGTGTAACACCAATTTA TCACGGTGAAGAAAGTCGTACAGAAGCAGGTGCAAAAGCAGCACTTCAATCATTAAAAGAAAAAGGTTATTTATCTACTG GCGATTTAGTACTGGTAACCCAAGGTGGTCAAGGTGCGACACAAACTAACGTATGTCGTACATTAATTGTTGAATAA Protein sequence : MSRRLRRTKIVCTMGPSTDRDNNLEKIIAAGANVVRMNFSHGTPDDHIGRAERVRSIAKKLGKTVAILGDLQGPKIRVST FKDGKIFLNVGDKFILDAELPKGEGTQESVGLDYKTLPQDVVPGDILLLDDGRVQLKVLSTDGAKVFTEVTVGGPLSNNK GINKLGGGLSADALTEKDKADIITAARIGVDFLAVSFPRSSADLNYARELAQQAGLNAKIVAKVERAETVANDEAMDDII LASDVIMVARGDLGVEIGDPELVGVQKKLIRRSRQLNRAVITATQMMESMISNPMPTRAEVMDVANAVLDGTDAVMLSAE TAAGQYPSETVAAMASVCLGAEKMPSINVSRHRMDKEFETIEESVAMSAMYAANHMKGVAAIVTLTSTGRTPLLMSRISS GLPIFALSRNQETLNLCALYRGVTPIYHGEESRTEAGAKAALQSLKEKGYLSTGDLVLVTQGGQGATQTNVCRTLIVE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykA | NP_273151.1 | pyruvate kinase | Not tested | IHT-A | Protein | 9e-78 | 49 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-55 | 41 |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 3e-55 | 41 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 7e-56 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| CGSHiEE_05445 | YP_001290848.1 | pyruvate kinase | VFG0479 | Protein | 1e-55 | 41 |
