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Name : TBFG_10389 (TBFG_10389) Accession : YP_001286334.1 Strain : Mycobacterium tuberculosis F11 Genome accession: NC_009565 Putative virulence/resistance : Virulence Product : endopeptidase ATP binding protein subunit B clpB Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 462624 - 465170 bp Length : 2547 bp Strand : - Note : Mapped to H37Rv Rv0384c DNA sequence : GTGGACTCGTTTAACCCGACGACCAAGACGCAGGCGGCGCTAACCGCGGCGTTACAGGCGGCTTCGACCGCCGGCAATCC CGAGATCCGGCCCGCTCACCTGCTGATGGCGCTGCTGACCCAAAACGACGGTATCGCCGCACCGCTACTGGAGGCTGTCG GTGTCGAGCCCGCCACCGTCCGCGCCGAAACCCAGCGCCTGCTCGACCGTTTGCCGCAGGCGACTGGAGCCAGCACGCAG CCGCAGCTGTCCCGCGAGTCGTTAGCGGCGATCACCACCGCGCAGCAGCTGGCCACCGAGCTGGACGACGAGTACGTCTC CACCGAGCACGTGATGGTCGGGCTGGCCACCGGTGACTCCGACGTCGCCAAGCTGTTGACCGGCCACGGCGCCTCGCCGC AGGCGCTGCGGGAGGCGTTCGTCAAGGTGCGCGGCAGCGCCCGGGTCACCAGCCCCGAACCGGAGGCGACCTATCAGGCG CTGCAGAAGTACTCCACCGACCTGACCGCCCGCGCCCGCGAAGGCAAACTCGACCCGGTCATCGGCCGCGACAACGAGAT CCGCCGCGTGGTGCAGGTGCTGTCCCGTCGCACCAAGAACAACCCGGTGCTGATCGGTGAGCCCGGCGTCGGCAAGACCG CGATCGTGGAGGGCCTGGCGCAGCGCATCGTGGCCGGCGACGTGCCGGAGAGCTTGCGCGACAAGACCATCGTCGCGCTC GATCTCGGCTCGATGGTCGCCGGCTCCAAATACCGCGGCGAATTCGAGGAACGGCTCAAGGCCGTCCTCGACGACATCAA GAACTCGGCCGGCCAAATCATCACGTTCATCGACGAGCTGCACACCATCGTCGGCGCCGGCGCCACCGGCGAGGGGGCGA TGGACGCCGGCAACATGATCAAGCCGATGCTGGCCCGCGGCGAGTTACGGCTGGTCGGGGCGACCACGCTGGACGAATAC CGCAAGCACATCGAGAAGGACGCCGCGCTCGAGCGCCGTTTCCAACAGGTGTACGTCGGCGAGCCGTCGGTGGAGGACAC CATCGGCATCCTGCGCGGGCTCAAAGACCGCTACGAGGTGCACCACGGGGTGCGCATCACCGACTCGGCGCTGGTGGCAG CTGCCACTTTGAGCGACCGGTATATCACCGCCCGCTTCCTGCCCGACAAGGCCATCGACCTGGTCGACGAGGCGGCCAGC CGGCTGCGGATGGAGATCGACTCGCGGCCCGTCGAGATCGACGAGGTCGAGCGGCTGGTGCGCCGGCTGGAGATCGAAGA GATGGCGCTGTCCAAAGAAGAAGACGAGGCGTCGGCGGAGCGGTTGGCCAAGCTGCGCTCCGAGCTGGCCGACCAGAAAG AGAAGTTGGCCGAGCTCACCACCCGCTGGCAGAACGAGAAGAACGCGATCGAAATCGTCCGCGACCTCAAGGAGCAGCTG GAAGCCCTGCGCGGGGAATCCGAGCGGGCCGAACGCGACGGCGACCTGGCCAAGGCCGCCGAGCTGCGCTACGGACGCAT CCCCGAGGTGGAGAAGAAGCTCGACGCGGCGTTGCCGCAGGCGCAGGCCCGGGAGCAGGTGATGCTCAAGGAGGAGGTCG GTCCCGACGACATCGCCGACGTGGTGTCGGCGTGGACCGGCATCCCGGCCGGTCGGCTGCTGGAAGGCGAGACCGCCAAG CTGCTGCGCATGGAAGACGAGCTGGGCAAGCGGGTCATCGGGCAGAAGGCCGCGGTTACCGCAGTCTCTGATGCGGTGCG GCGCAGCCGGGCCGGGGTGTCCGACCCCAACCGGCCCACCGGGGCGTTCATGTTCCTCGGCCCGACCGGTGTCGGCAAGA CCGAGCTGGCCAAGGCGCTGGCCGACTTCCTGTTCGACGACGAGCGGGCGATGGTCCGCATCGACATGAGCGAGTACGGC GAGAAGCACACCGTGGCTCGGTTGATCGGCGCCCCGCCCGGCTATGTGGGATACGAGGCGGGCGGTCAGCTGACCGAGGC GGTGCGCCGGCGTCCCTACACGGTGGTGCTGTTCGACGAGATCGAGAAGGCGCACCCGGACGTGTTCGACGTGCTGCTGC AGGTCCTCGACGAGGGCCGGCTCACCGACGGGCACGGCCGCACGGTCGACTTCCGCAACACCATCTTGATCCTGACGTCC AACCTGGGGTCGGGTGGCAGCGCCGAGCAGGTGCTGGCCGCGGTGCGCGCTACGTTCAAGCCGGAGTTCATCAACCGGCT CGACGACGTGCTCATCTTTGAGGGTCTCAACCCCGAAGAGCTGGTGCGCATCGTCGACATCCAGCTGGCGCAGCTGGGCA AGCGGCTGGCGCAGCGGCGGCTGCAGCTGCAGGTCTCGCTGCCGGCCAAGCGCTGGTTGGCGCAGCGCGGATTCGACCCG GTGTACGGGGCGCGGCCGTTGCGCCGGCTGGTGCAGCAGGCCATCGGTGACCAGCTGGCCAAGATGCTGTTGGCCGGCCA GGTGCACGACGGCGATACCGTGCCGGTCAACGTCAGCCCCGACGCCGACTCGCTGATCCTGGGCTGA Protein sequence : MDSFNPTTKTQAALTAALQAASTAGNPEIRPAHLLMALLTQNDGIAAPLLEAVGVEPATVRAETQRLLDRLPQATGASTQ PQLSRESLAAITTAQQLATELDDEYVSTEHVMVGLATGDSDVAKLLTGHGASPQALREAFVKVRGSARVTSPEPEATYQA LQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTIVAL DLGSMVAGSKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGEGAMDAGNMIKPMLARGELRLVGATTLDEY RKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAAS RLRMEIDSRPVEIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQL EALRGESERAERDGDLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDIADVVSAWTGIPAGRLLEGETAK LLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLFDDERAMVRIDMSEYG EKHTVARLIGAPPGYVGYEAGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTVDFRNTILILTS NLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPEELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLAQRGFDP VYGARPLRRLVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADSLILG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 1e-104 | 43 |
| aec27 | YP_851418.1 | ATPase | Not tested | PAI II APEC-O1 | Protein | 2e-105 | 42 |
| aec27 | AAQ96721.1 | Aec27 | Not tested | AGI-1 | Protein | 2e-105 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| TBFG_10389 | YP_001286334.1 | endopeptidase ATP binding protein subunit B clpB | VFG2076 | Protein | 4e-112 | 44 |
| TBFG_10389 | YP_001286334.1 | endopeptidase ATP binding protein subunit B clpB | VFG2084 | Protein | 1e-111 | 41 |
