Gene Information

Name : TBFG_10342 (TBFG_10342)
Accession : YP_001286287.1
Strain : Mycobacterium tuberculosis F11
Genome accession: NC_009565
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 404953 - 406242 bp
Length : 1290 bp
Strand : -
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
GTGGACAACGATGGCACCATTGTGGACGTGACAACCCACCAGCTGCCCTGGCACACCGCCAGCCATCAGCGGCAGCGCGC
CTTCGCTCAGTCGGCCAAGCTGCAGGACGTCCTGTACGAGATCCGCGGCCCGGTGCACCAGCACGCCGCGCGGCTCGAAG
CCGAAGGTCACCGCATCCTCAAACTCAACATCGGCAACCCGGCGCCGTTCGGCTTCGAAGCACCCGACGTGATCATGCGC
GATATCATCCAGGCGCTGCCCTACGCGCAGGGGTACTCCGACTCGCAGGGCATCCTGTCGGCCCGGCGTGCGGTGGTCAC
GCGCTACGAGCTGGTGCCCGGATTTCCCCGATTCGACGTGGACGACGTCTACCTGGGTAACGGGGTCTCCGAGCTGATCA
CGATGACGCTGCAAGCCCTGCTGGACAACGGCGATCAGGTGCTGATTCCATCACCGGACTACCCGCTGTGGACGGCGTCG
ACCTCGCTGGCTGGCGGCACTCCGGTCCACTACCTGTGCGATGAGACCCAAGGCTGGCAGCCCGATATCGCCGACCTGGA
ATCCAAGATCACCGAGCGCACCAAGGCGCTGGTCGTGATCAACCCCAACAACCCAACCGGCGCGGTGTACAGCTGCGAAA
TCCTCACCCAGATGGTCGATCTGGCCCGCAAGCATCAACTGCTGCTGTTGGCGGACGAAATCTACGACAAAATCCTCTAC
GACGACGCCAAGCACATCAGCCTGGCATCGATCGCCCCGGATATGTTGTGCCTGACCTTCAATGGGCTGTCGAAGGCCTA
CCGCGTCGCCGGATACCGGGCCGGCTGGCTGGCGATCACCGGACCCAAGGAGCACGCCAGCAGCTTCATCGAGGGCATCG
GCCTGCTGGCCAATATGCGGTTGTGCCCAAATGTCCCGGCCCAGCATGCCATTCAGGTTGCACTGGGCGGCCATCAGAGC
ATCGAGGACCTGGTGCTGCCCGGCGGCCGGCTGCTCGAGCAGCGCGACATCGCCTGGACCAAGCTCAACGAGATCCCGGG
GGTGTCGTGCGTCAAACCGGCGGGCGCGCTGTATGCGTTTCCCCGGCTAGACCCCGAGGTCTACGACATCGACGACGACG
AGCAACTCGTGCTCGATCTGCTGCTGTCGGAGAAGATCCTGGTCACCCAGGGCACCGGGTTCAACTGGCCCGCACCGGAT
CATCTGCGCCTGGTGACGCTGCCATGGTCCCGCGATCTGGCGGCCGCCATCGAGCGGCTGGGTAACTTCCTGGTCAGTTA
CCGGCAATAG

Protein sequence :
MDNDGTIVDVTTHQLPWHTASHQRQRAFAQSAKLQDVLYEIRGPVHQHAARLEAEGHRILKLNIGNPAPFGFEAPDVIMR
DIIQALPYAQGYSDSQGILSARRAVVTRYELVPGFPRFDVDDVYLGNGVSELITMTLQALLDNGDQVLIPSPDYPLWTAS
TSLAGGTPVHYLCDETQGWQPDIADLESKITERTKALVVINPNNPTGAVYSCEILTQMVDLARKHQLLLLADEIYDKILY
DDAKHISLASIAPDMLCLTFNGLSKAYRVAGYRAGWLAITGPKEHASSFIEGIGLLANMRLCPNVPAQHAIQVALGGHQS
IEDLVLPGGRLLEQRDIAWTKLNEIPGVSCVKPAGALYAFPRLDPEVYDIDDDEQLVLDLLLSEKILVTQGTGFNWPAPD
HLRLVTLPWSRDLAAAIERLGNFLVSYRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-144 72
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-144 72
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 3e-144 72
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 3e-144 72