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Name : smpB (TBFG_13117) Accession : YP_001289046.1 Strain : Mycobacterium tuberculosis F11 Genome accession: NC_009565 Putative virulence/resistance : Unknown Product : SsrA-binding protein Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0691 EC number : - Position : 3481065 - 3481547 bp Length : 483 bp Strand : - Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca DNA sequence : GTGTCCAAGTCGTCGCGTGGCGGCCGGCAGATCGTTGCCAGCAATCGCAAAGCCCGGCACAACTATTCGATCATCGAGGT GTTCGAGGCCGGGGTTGCGCTGCAAGGCACGGAGGTGAAGAGCCTGCGGGAAGGGCAGGCGTCGCTGGCCGATTCGTTCG CCACCATCGACGACGGCGAAGTGTGGCTGCGCAACGCGCACATCCCGGAATACCGGCACGGCAGCTGGACCAACCACGAG CCGCGACGCAACCGCAAACTGCTGTTGCATCGCCGCCAGATCGACACCTTGGTCGGCAAGATCCGCGAAGGCAACTTCGC CCTGGTGCCGTTGTCGCTGTATTTCGCCGAAGGCAAGGTCAAGGTTGAGCTTGCGCTGGCCCGAGGCAAGCAAGCCCGCG ACAAACGCCAGGACATGGCCCGTCGTGATGCCCAGCGTGAAGTGCTCCGCGAGTTGGGTCGGCGCGCTAAGGGCATGACC TGA Protein sequence : MSKSSRGGRQIVASNRKARHNYSIIEVFEAGVALQGTEVKSLREGQASLADSFATIDDGEVWLRNAHIPEYRHGSWTNHE PRRNRKLLLHRRQIDTLVGKIREGNFALVPLSLYFAEGKVKVELALARGKQARDKRQDMARRDAQREVLRELGRRAKGMT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| smpB | YP_001800894.1 | SsrA-binding protein | Not tested | Not named | Protein | 5e-49 | 67 |
| unnamed | AET14351.1 | SsrA-binding protein | Not tested | SaPI68111 | Protein | 4e-32 | 49 |
| smpB | NP_230495.1 | SsrA-binding protein | Not tested | VPI-1 | Protein | 4e-23 | 43 |
