Gene Information

Name : TBFG_12776 (TBFG_12776)
Accession : YP_001288705.1
Strain : Mycobacterium tuberculosis F11
Genome accession: NC_009565
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase dfrA (tetrahydrofolate dehydrogenase)
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : -
Position : 3085085 - 3085564 bp
Length : 480 bp
Strand : -
Note : Mapped to H37Rv Rv2763c

DNA sequence :
ATGGTGGGGCTGATCTGGGCTCAAGCGACATCGGGTGTCATCGGCCGCGGCGGCGACATCCCCTGGCGCTTGCCCGAGGA
CCAGGCGCATTTCCGGGAGATCACCATGGGGCACACGATCGTGATGGGCCGGCGCACATGGGATTCGCTGCCGGCTAAAG
TCCGGCCGCTGCCCGGCCGGCGAAATGTCGTACTGAGCCGCCAAGCTGACTTTATGGCCAGCGGGGCTGAGGTTGTCGGT
TCACTCGAGGAGGCGCTGACCAGCCCGGAGACGTGGGTGATCGGAGGCGGACAAGTCTATGCGCTGGCGCTGCCGTACGC
GACCAGATGTGAGGTTACCGAGGTCGACATCGGCCTGCCGCGCGAAGCCGGTGACGCGCTGGCCCCCGTGCTGGACGAGA
CATGGCGGGGCGAGACGGGGGAGTGGCGCTTCAGCCGGTCCGGGTTGCGGTACCGGTTGTACAGCTACCACCGCTCATGA

Protein sequence :
MVGLIWAQATSGVIGRGGDIPWRLPEDQAHFREITMGHTIVMGRRTWDSLPAKVRPLPGRRNVVLSRQADFMASGAEVVG
SLEEALTSPETWVIGGGQVYALALPYATRCEVTEVDIGLPREAGDALAPVLDETWRGETGEWRFSRSGLRYRLYSYHRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 5e-19 41