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Name : lysS (MRA_3638) Accession : YP_001284986.1 Strain : Mycobacterium tuberculosis H37Ra Genome accession: NC_009525 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 4050088 - 4051605 bp Length : 1518 bp Strand : - Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : GTGAGTGCCGCTGACACAGCAGAAGACCTTCCTGAGCAGTTCCGGATTCGCCGGGACAAGCGCGCTCGCTTGCTGGCCCA GGGGCGCGATCCCTATCCCGTCGCGGTGCCGCGCACTCACACGTTGGCCGAGGTTCGCGCCGCCCACCCTGACTTGCCGA TCGATACCGCGACCGAAGACATCGTCGGCGTCGCGGGCCGAGTGATCTTTGCGCGCAACTCGGGAAAGCTATGCTTTGCG ACACTTCAGGACGGCGATGGTACCCAGCTGCAAGTGATGATCAGCCTCGACAAGGTCGGCCAGGCTGCTCTCGACGCATG GAAAGCCGATGTCGACCTGGGCGACATCGTCTACGTGCATGGCGCGGTGATCAGTTCGCGCCGCGGCGAGCTGTCCGTCC TGGCGGATTGCTGGCGGATCGCCGCCAAGTCGCTGCGGCCGCTTCCCGTCGCGCACAAAGAGATGAGTGAAGAGTCGCGG GTTCGTCAGCGCTATGTTGACCTCATAGTTCGACCGGAAGCGCGCGCGGTGGCTCGACTACGGATCGCCGTCGTCCGCGC GATCCGGACGGCGCTTCAACGTCGTGGGTTCCTGGAAGTCGAGACGCCCGTCTTGCAGACGTTAGCCGGTGGTGCGGCGG CCCGTCCGTTCGCCACTCATTCCAATGCCCTAGACATCGATCTGTACCTGCGGATCGCGCCGGAACTGTTCCTCAAGCGC TGCATCGTGGGTGGTTTCGACAAGGTCTTCGAACTTAATCGAGTGTTCCGAAACGAAGGAGCCGATTCCACGCATTCTCC GGAATTCTCCATGCTGGAGACCTACCAGACCTACGGAACCTATGACGATTCGGCAGTCGTCACCCGGGAGCTTATTCAAG AGGTGGCCGATGAGGCGATCGGAACCAGACAACTGCCGTTGCCCGACGGCAGTGTCTATGACATCGACGGAGAATGGGCG ACTATACAAATGTACCCGTCGCTGTCTGTGGCGCTCGGTGAAGAGATCACACCGCAGACGACGGTCGATCGCTTACGTGG GATCGCCGATAGCCTTGGCCTGGAGAAAGACCCAGCGATTCATGACAACCGTGGCTTCGGCCACGGCAAACTCATCGAGG AACTCTGGGAGCGCACAGTGGGCAAGAGCTTGAGCGCACCCACATTTGTCAAGGATTTTCCGGTTCAGACAACGCCTTTG ACCCGTCAGCACCGCAGTATCCCCGGCGTAACCGAGAAGTGGGACCTCTATCTGCGCGGAATCGAACTTGCCACCGGCTA CTCGGAATTAAGCGACCCGGTAGTCCAGCGGGAGAGATTCGCCGACCAGGCCCGTGCCGCGGCCGCTGGCGATGACGAAG CGATGGTGCTTGACGAGGATTTTCTGGCCGCTCTGGAGTACGGCATGCCACCGTGCACCGGAACCGGAATGGGTATCGAT CGGTTGTTGATGTCTTTGACTGGGTTGTCAATTAGGGAGACAGTTTTGTTCCCGATTGTTCGACCACACTCCAACTGA Protein sequence : MSAADTAEDLPEQFRIRRDKRARLLAQGRDPYPVAVPRTHTLAEVRAAHPDLPIDTATEDIVGVAGRVIFARNSGKLCFA TLQDGDGTQLQVMISLDKVGQAALDAWKADVDLGDIVYVHGAVISSRRGELSVLADCWRIAAKSLRPLPVAHKEMSEESR VRQRYVDLIVRPEARAVARLRIAVVRAIRTALQRRGFLEVETPVLQTLAGGAAARPFATHSNALDIDLYLRIAPELFLKR CIVGGFDKVFELNRVFRNEGADSTHSPEFSMLETYQTYGTYDDSAVVTRELIQEVADEAIGTRQLPLPDGSVYDIDGEWA TIQMYPSLSVALGEEITPQTTVDRLRGIADSLGLEKDPAIHDNRGFGHGKLIEELWERTVGKSLSAPTFVKDFPVQTTPL TRQHRSIPGVTEKWDLYLRGIELATGYSELSDPVVQRERFADQARAAAAGDDEAMVLDEDFLAALEYGMPPCTGTGMGID RLLMSLTGLSIRETVLFPIVRPHSN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 6e-142 | 61 |
