Gene Information

Name : purA (MRA_0366)
Accession : YP_001281646.1
Strain : Mycobacterium tuberculosis H37Ra
Genome accession: NC_009525
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 436834 - 438132 bp
Length : 1299 bp
Strand : -
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGCCGGCGATCGTCCTCATCGGCGCCCAATGGGGCGACGAGGGCAAGGGTAAGGCCACCGACCTGTTGGGTGGCCGCGT
GCAGTGGGTGGTGCGCTATCAGGGGGGCAACAACGCCGGGCACACCGTCGTCTTGCCTACCGGCGAGAATTTCGCATTGC
ATCTCATCCCGTCGGGTGTGCTGACGCCCGGGGTCACCAACGTTATCGGCAACGGCGTGGTGATCGATCCCGGTGTCCTG
CTCAATGAGCTGCGGGGACTGCAAGACCGCGGCGTGGACACCGCCAAGCTGTTGATCTCCGCCGACGCCCATCTGCTGAT
GCCTTACCACATTGCTATCGACAAGGTCACCGAGCGCTATATGGGCAGCAAGAAGATCGGCACCACCGGCCGTGGTATCG
GGCCGTGCTACCAGGACAAGATCGCCCGTATTGGGATCCGGGTCGCCGATGTGCTGGACCCGGAACAATTGACCCACAAG
GTCGAGGCCGCGTGCGAGTTCAAGAACCAAGTGCTGGTCAAGATCTACAACCGCAAGGCCCTGGACCCCGCGCAGGTGGT
CGACGCGCTGCTGGAGCAGGCCGAGGGTTTCAAGCATCGCATCGCCGACACCCGGCTGCTACTCAATGCTGCCCTGGAGG
CCGGCGAAACGGTGCTGCTGGAAGGCTCTCAAGGCACCCTGCTCGATGTCGACCACGGCACCTACCCGTATGTGACATCG
TCGAATCCGACGGCGGGTGGCGCGGCCGTGGGCTCTGGTATCGGCCCGACCCGCATCGGCACCGTGCTGGGGATTCTCAA
GGCCTACACCACTCGGGTGGGCTCCGGCCCGTTCCCCACCGAGCTGTTCGACGAACACGGCGAATACCTGTCCAAGACTG
GCCGCGAGTTCGGTGTGACCACCGGCCGGCGCCGGCGCTGCGGCTGGTTCGACGCCGTCATTGCCCGCTACGCCGCCCGG
GTCAACGGCATCACCGACTACTTCCTGACCAAGCTCGACGTGCTGTCCAGCCTGGAATCGGTGCCGGTCTGCGTCGGATA
TGAGATCGACGGCCGGCGCACCCGCGATATGCCGATGACCCAGCGGGATCTTTGCCGCGCCAAGCCGGTTTACGAGGAGC
TGCCGGGCTGGTGGGAAGACATCTCCGGGGCGCGCGAGTTCGACGACCTGCCCGCCAAAGCGCGTGATTATGTGCTGCGA
CTGGAACAGCTTGCCGGAGCACCGGTTTCGTGCATTGGAGTCGGTCCGGGGCGGGAACAGACCATCGTGCGCCGGGACGT
CCTGCAGGATCGCCCGTGA

Protein sequence :
MPAIVLIGAQWGDEGKGKATDLLGGRVQWVVRYQGGNNAGHTVVLPTGENFALHLIPSGVLTPGVTNVIGNGVVIDPGVL
LNELRGLQDRGVDTAKLLISADAHLLMPYHIAIDKVTERYMGSKKIGTTGRGIGPCYQDKIARIGIRVADVLDPEQLTHK
VEAACEFKNQVLVKIYNRKALDPAQVVDALLEQAEGFKHRIADTRLLLNAALEAGETVLLEGSQGTLLDVDHGTYPYVTS
SNPTAGGAAVGSGIGPTRIGTVLGILKAYTTRVGSGPFPTELFDEHGEYLSKTGREFGVTTGRRRRCGWFDAVIARYAAR
VNGITDYFLTKLDVLSSLESVPVCVGYEIDGRRTRDMPMTQRDLCRAKPVYEELPGWWEDISGAREFDDLPAKARDYVLR
LEQLAGAPVSCIGVGPGREQTIVRRDVLQDRP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 1e-102 52