Gene Information

Name : ureA (MRA_1859)
Accession : YP_001283177.1
Strain : Mycobacterium tuberculosis H37Ra
Genome accession: NC_009525
Putative virulence/resistance : Unknown
Product : urease subunit gamma
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0831
EC number : 3.5.1.5
Position : 2107280 - 2107582 bp
Length : 303 bp
Strand : +
Note : UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter

DNA sequence :
ATGCGCCTGACGCCGCACGAACAGGAGCGTTTGCTGTTGTCCTACGCCGCCGAGTTGGCCCGCCGGCGTCGGGCCCGCGG
CCTGCGCCTCAATCATCCGGAAGCCATCGCGGTGATCGCCGACCACATCCTGGAAGGCGCGCGTGACGGCCGCACCGTCG
CAGAGTTGATGGCATCCGGGCGTGAGGTGCTCGGCCGTGACGATGTGATGGAGGGAGTGCCGGAGATGCTCGCCGAGGTA
CAGGTGGAGGCGACGTTTCCGGACGGCACCAAGTTGGTCACCGTGCATCAGCCGATCGCATGA

Protein sequence :
MRLTPHEQERLLLSYAAELARRRRARGLRLNHPEAIAVIADHILEGARDGRTVAELMASGREVLGRDDVMEGVPEMLAEV
QVEATFPDGTKLVTVHQPIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureA YP_005682176.1 urease subunit gamma Not tested PiCp 7 Protein 1e-21 68
ureA YP_005684268.1 urease subunit gamma Not tested PiCp 7 Protein 1e-21 68
ureA YP_003784327.1 urease subunit gamma Not tested PiCp 7 Protein 1e-21 68
ureA YP_005686360.1 urease subunit gamma Not tested PiCp 7 Protein 1e-21 68