Gene Information

Name : trpE (MRA_1619)
Accession : YP_001282927.1
Strain : Mycobacterium tuberculosis H37Ra
Genome accession: NC_009525
Putative virulence/resistance : Unknown
Product : anthranilate synthase component I
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 1809421 - 1810971 bp
Length : 1551 bp
Strand : +
Note : with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine

DNA sequence :
GTGCACGCCGACCTCGCAGCCACCACCTCGCGTGAGGATTTCCGCCTCCTGGCGGCCGAGCACCGGGTGGTTCCGGTGAC
TCGCAAGGTCTTGGCCGACAGCGAGACGCCGCTGTCGGCCTACCGCAAGCTCGCCGCCAATCGCCCGGGTACGTTCCTGC
TGGAGTCGGCCGAGAACGGCCGGTCGTGGTCGCGATGGTCGTTTATCGGTGCGGGGGCGCCAACGGCGTTGACCGTGCGT
GAGGGGCAAGCGGTATGGCTGGGTGCCGTGCCCAAGGACGCTCCCACTGGCGGAGACCCGCTGCGGGCGCTGCAGGTGAC
CTTGGAGCTGCTGGCTACGGCGGATCGTCAGTCCGAGCCGGGTCTTCCGCCGCTGTCGGGTGGCATGGTCGGTTTCTTCG
CCTATGACATGGTGCGACGGCTGGAACGATTGCCGGAACGGGCCGTCGATGACCTCTGCCTGCCGGACATGCTGCTGTTG
CTGGCCACCGATGTGGCGGCGGTCGATCACCACGAGGGCACCATCACGTTGATCGCCAACGCCGTGAACTGGAACGGCAC
CGACGAGCGGGTCGACTGGGCCTACGACGACGCGGTCGCTCGGCTGGACGTGATGACCGCAGCGCTCGGCCAACCACTAC
CGTCAACCGTGGCCACCTTCAGCCGACCCGAGCCGCGCCACCGTGCGCAACGCACCGTCGAAGAATATGGTGCGATCGTC
GAATACTTGGTGGATCAGATTGCAGCCGGTGAAGCGTTCCAGGTGGTGCCCTCGCAGCGCTTCGAGATGGACACCGATGT
CGATCCCATCGACGTGTACCGAATTCTGCGGGTAACCAACCCAAGTCCCTACATGTATCTACTGCAGGTGCCGAATAGTG
ATGGTGCAGTGGACTTTTCGATTGTTGGATCCAGTCCGGAGGCGCTGGTAACGGTCCACGAAGGCTGGGCGACGACGCAT
CCGATCGCCGGAACCCGGTGGCGCGGAAGGACAGACGACGAGGACGTGCTTCTGGAAAAAGAGCTGCTGGCGGACGACAA
AGAACGTGCCGAGCATCTGATGCTGGTCGACCTCGGCCGAAACGACCTGGGTCGGGTCTGCACGCCGGGCACTGTTCGGG
TCGAGGATTACAGCCACATCGAGCGGTACAGCCACGTGATGCACCTGGTGTCCACGGTGACCGGGAAGCTCGGCGAAGGG
CGCACCGCGCTGGACGCGGTGACCGCCTGCTTTCCGGCCGGCACGCTGTCGGGCGCGCCGAAGGTGCGGGCGATGGAGCT
GATCGAAGAGGTGGAGAAGACACGCCGCGGCCTTTACGGCGGTGTCGTCGGTTACCTTGACTTCGCCGGCAACGCTGACT
TCGCCATCGCCATCCGCACCGCGCTGATGCGTAACGGCACGGCTTATGTCCAGGCAGGCGGTGGTGTGGTGGCCGACTCC
AACGGATCCTACGAATACAACGAGGCGAGGAACAAGGCTCGGGCTGTGCTCAACGCGATCGCTGCCGCCGAGACGCTGGC
CGCTCCGGGCGCGAACCGCAGTGGCTGCTAA

Protein sequence :
MHADLAATTSREDFRLLAAEHRVVPVTRKVLADSETPLSAYRKLAANRPGTFLLESAENGRSWSRWSFIGAGAPTALTVR
EGQAVWLGAVPKDAPTGGDPLRALQVTLELLATADRQSEPGLPPLSGGMVGFFAYDMVRRLERLPERAVDDLCLPDMLLL
LATDVAAVDHHEGTITLIANAVNWNGTDERVDWAYDDAVARLDVMTAALGQPLPSTVATFSRPEPRHRAQRTVEEYGAIV
EYLVDQIAAGEAFQVVPSQRFEMDTDVDPIDVYRILRVTNPSPYMYLLQVPNSDGAVDFSIVGSSPEALVTVHEGWATTH
PIAGTRWRGRTDDEDVLLEKELLADDKERAEHLMLVDLGRNDLGRVCTPGTVRVEDYSHIERYSHVMHLVSTVTGKLGEG
RTALDAVTACFPAGTLSGAPKVRAMELIEEVEKTRRGLYGGVVGYLDFAGNADFAIAIRTALMRNGTAYVQAGGGVVADS
NGSYEYNEARNKARAVLNAIAAAETLAAPGANRSGC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00338 YP_008207803.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR25 Protein 2e-65 44
BJAB0868_00342 YP_008211668.1 Anthranilate/para-aminobenzoate synthases component I Not tested AbaR26 Protein 2e-65 44