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Name : tkt (MRA_1458) Accession : YP_001282764.1 Strain : Mycobacterium tuberculosis H37Ra Genome accession: NC_009525 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 1629407 - 1631509 bp Length : 2103 bp Strand : - Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : GTGACCACACTCGAAGAGATCTCCGCGCTTACCCGACCGCGCCATCCCGACTACTGGACCGAGATCGATTCGGCTGCCGT CGACACCATCCGGGTATTGGCCGCCGATGCCGTCCAAAAGGTCGGCAACGGTCATCCTGGAACGGCGATGAGCCTGGCTC CGTTGGCCTACACGCTGTTTCAGCGGACAATGCGTCACGATCCCAGCGACACACACTGGCTGGGCCGCGATCGGTTCGTT TTGTCGGCCGGGCACAGCAGCCTGACCCTCTACATCCAGCTCTACCTCGGCGGCTTCGGCCTGGAACTGTCCGACATTGA GTCGTTGCGCACCTGGGGATCCAAGACCCCCGGACACCCGGAGTTCCGCCACACCCCCGGCGTTGAGATCACCACCGGCC CGCTGGGGCAGGGACTGGCGTCGGCGGTCGGGATGGCGATGGCCTCGCGCTACGAGCGCGGCCTGTTCGACCCGGACGCC GAACCGGGCGCCAGCCCCTTCGACCACTACATCTATGTCATCGCCTCCGACGGTGACATCGAAGAAGGGGTGACCTCGGA GGCGTCGTCGCTGGCCGCGGTCCAGCAACTGGGCAACCTCATCGTGTTCTACGACCGCAACCAGATCTCGATCGAGGACG ACACCAACATCGCGCTGTGTGAGGACACCGCGGCCCGCTACCGCGCGTACGGCTGGCACGTGCAAGAGGTTGAGGGCGGT GAGAACGTCGTCGGCATCGAGGAGGCCATCGCCAATGCGCAGGCGGTCACCGACCGGCCCTCGTTCATCGCGCTGCGCAC CGTCATCGGCTATCCGGCGCCGAACCTGATGGACACCGGCAAGGCGCACGGCGCGGCGCTGGGCGACGACGAGGTGGCCG CAGTCAAGAAGATCGTCGGCTTCGATCCGGACAAGACGTTCCAGGTCCGCGAGGACGTCCTCACCCACACCCGAGGGCTG GTGGCCCGCGGCAAACAGGCCCACGAACGCTGGCAGCTCGAATTCGATGCCTGGGCGCGGCGTGAACCCGAGCGCAAGGC GCTGCTGGACCGGCTGCTCGCGCAGAAGTTGCCCGACGGCTGGGACGCCGACTTGCCCCACTGGGAACCGGGGTCCAAGG CGCTGGCCACCCGTGCGGCCTCGGGTGCGGTGCTGTCCGCGCTCGGGCCGAAACTGCCCGAGTTGTGGGGCGGTTCGGCC GACCTGGCGGGCAGCAACAACACAACGATAAAGGGCGCCGACTCCTTTGGCCCGCCCTCGATTTCCACCAAGGAGTACAC CGCGCACTGGTATGGTCGCACCTTGCACTTCGGTGTTCGCGAGCACGCGATGGGTGCCATCCTGTCCGGCATCGTGCTGC ACGGACCCACCCGGGCTTACGGCGGCACCTTCCTGCAGTTCTCCGACTACATGCGCCCGGCGGTGCGGCTGGCGGCGTTG ATGGACATCGACACCATCTACGTCTGGACGCACGACTCGATCGGCCTCGGCGAAGACGGGCCCACCCATCAACCGATCGA GCACCTCTCGGCGCTGCGCGCGATCCCCCGGCTGTCGGTGGTGCGCCCGGCAGATGCCAACGAGACAGCCTACGCCTGGC GCACGATCCTGGCCCGCCGCAACGGCAGCGGGCCGGTCGGGTTGATCCTGACCCGCCAGGGTGTGCCGGTGCTGGACGGC ACCGACGCCGAGGGGGTTGCCCGCGGCGGTTACGTGCTGAGTGACGCCGGTGGTCTGCAACCGGGCGAGGAACCCGACGT CATTCTCATCGCCACCGGCTCGGAGGTGCAGCTGGCGGTCGCGGCGCAGACGTTGCTGGCGGACAACGACATCCTCGCTC GGGTGGTGTCGATGCCGTGCCTGGAGTGGTTCGAGGCCCAACCCTACGAGTACCGCGACGCGGTGCTGCCCCCGACGGTG TCGGCGCGGGTGGCCGTCGAAGCCGGCGTCGCGCAATGCTGGCACCAGCTGGTTGGCGACACGGGCGAGATCGTCTCGAT CGAGCACTACGGCGAATCCGCGGACCACAAGACCTTGTTCCGCGAGTACGGCTTCACTGCCGAGGCCGTGGCCGCCGCCG CCGAACGAGCGCTGGATAACTGA Protein sequence : MTTLEEISALTRPRHPDYWTEIDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFV LSAGHSSLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA EPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRNQISIEDDTNIALCEDTAARYRAYGWHVQEVEGG ENVVGIEEAIANAQAVTDRPSFIALRTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGL VARGKQAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLSALGPKLPELWGGSA DLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAAL MDIDTIYVWTHDSIGLGEDGPTHQPIEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVPVLDG TDAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLEWFEAQPYEYRDAVLPPTV SARVAVEAGVAQCWHQLVGDTGEIVSIEHYGESADHKTLFREYGFTAEAVAAAAERALDN |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 4e-113 | 44 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 1e-112 | 42 |
