Gene Information

Name : MRA_1338 (MRA_1338)
Accession : YP_001282642.1
Strain : Mycobacterium tuberculosis H37Ra
Genome accession: NC_009525
Putative virulence/resistance : Unknown
Product : nicotinate phosphoribosyltransferase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1488
EC number : 2.4.2.11
Position : 1500523 - 1501869 bp
Length : 1347 bp
Strand : -
Note : catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate

DNA sequence :
GTGGGGCCACCCCCAGCCGCCAGGCGGCGAGAGGGAGAGCCCGACAATCAAGACCCAGCCGGGCTGTTGACCGACAAGTA
CGAGTTGACCATGCTGGCGGCTGCCCTGCGCGACGGCAGCGCCAATCGCCCCACCACATTCGAGGTGTTCGCTCGCCGAC
TCCCCACCGGCCGTCGCTACGGAGTTGTCGCCGGAACCGGCCGGTTGCTGGAAGCGTTGCCGCAGTTCAGGTTCGACGCT
GACGCGTGCGAGTTGCTGGCCCAATTCCTCGACCCGGCCACGGTGCGGTATCTTCGCGAATTCCGGTTCCGCGGCGATAT
CGACGGCTATGCCGAGGGGGAGCTGTATTTTCCCGGGTCACCGGTGCTCTCGGTACGCGGCAGCTTCGCCGAATGCGTCC
TGCTCGAAACGCTGGTGCTGTCAATCTTCAACCACGACACAGCGATCGCCTCGGCAGCGGCGCGCATGGTCAGCGCCGCC
GGGGGGCGCCCACTGATCGAGATGGGCTCGCGGCGCACCCACGAACGCGCCGCGGTGGCAGCGGCCCGGGCGGCGTATAT
CGCCGGTTTCGCCGCGTCATCCAACTTGGCGGCGCAGCGACGCTACGGAGTGCCCGCGCACGGCACCGCGGCACACGCAT
TCACCATGTTGCACGCCCAGCATGGCGGCCCCACCGAACTAGCCGAGCGAGCCGCATTCCGCGCCCAGGTCGAAGCGCTG
GGACCCGGTACCACGCTGCTGGTGGATACCTATGACGTCACGACCGGTGTGGCCAATGCCGTTGCCGCCGCCGGCGCTGA
GCTCGGCGCGATCCGCATCGATTCCGGTGAGCTTGGGGTACTGGCCCGCCAAGCGCGGGAGCAGCTCGACCGGCTAGGAG
CCACCCGGACGCGCATCGTGGTGTCCGGCGACCTTGACGAGTTCAGCATCGCCGCGTTGCGCGGTGAACCCGTCGACAGC
TACGGCGTGGGCACGTCGCTGGTCACCGGGTCGGGCGCGCCGACCGCCAACATGGTCTACAAACTGGTCGAGGTAGACGG
TGTACCGGTGCAAAAGCGCAGCAGCTACAAAGAATCCCCCGGCGGCCGCAAAGAGGCACTGCGGCGCTCCCGTGCGACGG
GCACCATCACCGAGGAGCTCGTGCATCCGGCGGGCCGTCCGCCGGTCATTGTCGAGCCGCACCGGGTTTTGACGCTGCCA
CTGGTCCGCGCCGGGCAACCGGTAGCCGATACCAGCCTGGCCGCGGCACGGCAGCTGGTGGCATCCGGGTTGCGCAGCCT
GCCAGGCGACGGGCTGAAATTGGCACCCGGCGAGCCGGCGATTCCGACACGCACGATCCCGGCCTGA

Protein sequence :
MGPPPAARRREGEPDNQDPAGLLTDKYELTMLAAALRDGSANRPTTFEVFARRLPTGRRYGVVAGTGRLLEALPQFRFDA
DACELLAQFLDPATVRYLREFRFRGDIDGYAEGELYFPGSPVLSVRGSFAECVLLETLVLSIFNHDTAIASAAARMVSAA
GGRPLIEMGSRRTHERAAVAAARAAYIAGFAASSNLAAQRRYGVPAHGTAAHAFTMLHAQHGGPTELAERAAFRAQVEAL
GPGTTLLVDTYDVTTGVANAVAAAGAELGAIRIDSGELGVLARQAREQLDRLGATRTRIVVSGDLDEFSIAALRGEPVDS
YGVGTSLVTGSGAPTANMVYKLVEVDGVPVQKRSSYKESPGGRKEALRRSRATGTITEELVHPAGRPPVIVEPHRVLTLP
LVRAGQPVADTSLAAARQLVASGLRSLPGDGLKLAPGEPAIPTRTIPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1473 YP_001800867.1 nicotinate phosphoribosyltransferase Not tested Not named Protein 1e-95 62