Gene Information

Name : kdpB (MRA_1038)
Accession : YP_001282336.1
Strain : Mycobacterium tuberculosis H37Ra
Genome accession: NC_009525
Putative virulence/resistance : Unknown
Product : potassium-transporting ATPase subunit B
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2216
EC number : 3.6.3.12
Position : 1155032 - 1157161 bp
Length : 2130 bp
Strand : +
Note : One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions

DNA sequence :
GTGATGATCGCACGCATGGAGACCTCCGCAACCGCCGCGGCAGCGACGTCGGCACCCCGGCTCCGGCTGGCCAAGCGCTC
GCTGTTCGATCCGATGATTGTGCGCTCGGCGCTGCCCCAGAGCCTGCGCAAGCTGGCTCCGCGGGTACAGGCCCGTAACC
CGGTCATGTTGGTCGTGCTGGTCGGTGCCGTGATCACCACACTGGCGTTCCTGCGCGACCTCGCATCCTCGACAGCCCAA
GAGAACGTCTTCAACGGTCTGGTCGCCGCGTTCCTCTGGTTCACCGTCCTGTTTGCCAACTTTGCCGAGGCCATGGCCGA
AGGACGCGGCAAGGCTCAGGCGGCGGCGCTGCGCAAAGTCCGGTCCGAAACGATGGCCAACCGGCGCACGGCTGCGGGCA
ACATCGAATCGGTCCCTTCGTCGCGGCTGGACCTCGACGACGTGGTGGAGGTTTCGGCTGGCGAAACGATCCCGTCGGAC
GGCGAGATCATCGAAGGCATTGCCTCCGTCGACGAGTCTGCGATCACCGGCGAATCGGCACCGGTGATCCGCGAGTCGGG
CGGCGACCGTTCCGCGGTGACGGGTGGCACCGTGGTGCTGTCGGATCGGATCGTCGTGCGGATCACCGCCAAGCAGGGAC
AAACATTCATCGACCGGATGATCGCGCTGGTGGAGGGCGCCGCACGGCAGCAGACACCGAACGAGATCGCGCTGAACATC
CTGCTGGCTGGGCTGACGATCATCTTTTTGCTCGCGGTGGTGACGCTGCAGCCGTTCGCCATCTATTCCGGCGGGGGACA
GCGGGTGGTCGTGCTGGTGGCGTTGCTGGTGTGTCTCATTCCGACCACGATCGGTGCGCTGCTGTCCGCGATCGGCATCG
CGGGGATGGACCGGCTGGTGCAACACAACGTGCTCGCCACATCTGGGCGGGCGGTGGAGGCGGCCGGCGACGTGAACACG
CTGCTGCTGGACAAGACCGGCACCATCACCCTCGGTAACCGGCAGGCCACCGAGTTCGTGCCGATCAACGGTGTGAGTGC
CGAGGCGGTCGCCGACGCCGCCCAGCTGTCGAGCTTGGCCGACGAAACTCCGGAGGGCCGCTCGATCGTCGTGCTGGCGA
AGGACGAGTTCGGGCTGCGCGCCCGCGACGAGGGCGTGATGTCACACGCCAGGTTCGTGCCGTTCACCGCCGAAACCCGG
ATGTCCGGGGTCGATCTCGCCGAGGTTAGCGGCATCCGTCGGATCCGCAAGGGTGCCGCGGCTGCGGTGATGAAGTGGGT
TCGCGATCACGGTGGCCACCCCACCGAGGAGGTGGGTGCCATTGTCGACGGCATCAGCTCCGGCGGGGGGACACCCCTAG
TCGTTGCGGAATGGACCGATAACAGCAGCGCGCGGGCCATCGGCGTCGTCCATCTGAAGGACATCGTCAAGGTGGGCATA
CGGGAACGCTTCGACGAAATGCGCCGAATGAGCATCCGCACCGTGATGATCACCGGTGACAACCCGGCGACCGCCAAGGC
GATTGCACAGGAGGCCGGCGTCGACGATTTCTTGGCCGAGGCCACGCCCGAGGACAAGCTTGCGCTCATCAAGCGCGAAC
AGCAGGGCGGTCGGCTGGTCGCCATGACGGGTGACGGGACCAATGACGCACCCGCGCTCGCGCAAGCCGATGTCGGGGTG
GCGATGAATACCGGCACCCAGGCGGCCCGGGAAGCCGGCAACATGGTCGATCTCGACTCCGACCCCACCAAGCTCATCGA
GGTCGTGGAGATCGGCAAGCAGCTGCTGATCACGCGGGGCGCGCTGACGACGTTTTCGATCGCCAACGACGTCGCGAAGT
ACTTCGCCATCATCCCTGCCATGTTCGTCGGCCTGTATCCGGTGCTCGACAAGCTGAACGTCATGGCGCTGCACTCACCA
AGGTCGGCGATTCTGTCGGCGGTCATCTTCAATGCGCTGGTGATCGTCGCCTTGATCCCATTGGCGTTGCGGGGCGTGCG
GTTTAGGGCGGAAAGCGCGTCGGCGATGCTGCGGCGCAACCTGCTGATCTATGGGCTGGGCGGTCTCGTCGTCCCGTTTA
TCGGCATTAAACTGGTCGATCTCGTCATCGTCGCCCTCGGGGTGTCCTGA

Protein sequence :
MMIARMETSATAAAATSAPRLRLAKRSLFDPMIVRSALPQSLRKLAPRVQARNPVMLVVLVGAVITTLAFLRDLASSTAQ
ENVFNGLVAAFLWFTVLFANFAEAMAEGRGKAQAAALRKVRSETMANRRTAAGNIESVPSSRLDLDDVVEVSAGETIPSD
GEIIEGIASVDESAITGESAPVIRESGGDRSAVTGGTVVLSDRIVVRITAKQGQTFIDRMIALVEGAARQQTPNEIALNI
LLAGLTIIFLLAVVTLQPFAIYSGGGQRVVVLVALLVCLIPTTIGALLSAIGIAGMDRLVQHNVLATSGRAVEAAGDVNT
LLLDKTGTITLGNRQATEFVPINGVSAEAVADAAQLSSLADETPEGRSIVVLAKDEFGLRARDEGVMSHARFVPFTAETR
MSGVDLAEVSGIRRIRKGAAAAVMKWVRDHGGHPTEEVGAIVDGISSGGGTPLVVAEWTDNSSARAIGVVHLKDIVKVGI
RERFDEMRRMSIRTVMITGDNPATAKAIAQEAGVDDFLAEATPEDKLALIKREQQGGRLVAMTGDGTNDAPALAQADVGV
AMNTGTQAAREAGNMVDLDSDPTKLIEVVEIGKQLLITRGALTTFSIANDVAKYFAIIPAMFVGLYPVLDKLNVMALHSP
RSAILSAVIFNALVIVALIPLALRGVRFRAESASAMLRRNLLIYGLGGLVVPFIGIKLVDLVIVALGVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kdpB NP_814334.1 potassium-transporting ATPase subunit B Not tested Not named Protein 4e-173 62
ef0088 AAM75291.1 EF0088 Not tested Not named Protein 3e-173 62
kdpB NP_373310.1 potassium-transporting ATPase subunit B Not tested Type-II SCCmec Protein 5e-151 56
kdpB YP_190029.1 potassium-transporting ATPase subunit B Not tested Type-II SCCmec Protein 5e-151 56
kdpB BAA82181.1 potassium-transporting ATPase(B chanin) Not tested Type-II SCCmec Protein 3e-151 56
SAR0071 YP_039539.1 potassium-transporting ATPase subunit B Not tested Type-II SCCmec Protein 5e-151 56
kdpB(SCCmec) NP_370597.1 potassium-transporting ATPase subunit B Not tested Type-II SCCmec Protein 5e-151 56
kdpB YP_251949.1 potassium-transporting ATPase subunit B Not tested SCCmec Protein 3e-151 56