Gene Information

Name : thyA (PsycPRwf_2331)
Accession : YP_001281221.1
Strain : Psychrobacter sp. PRwf-1
Genome accession: NC_009524
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 2899060 - 2899920 bp
Length : 861 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGATAACTTCCAAAAATGAAGCCGCTTATCTTGATTTAATTCGCTATGTGCGTGACCACGGTACCGAGAAGGGAGACCG
TACAGGTACGGGCACCCGCAGTCATTTTGGCGCTCAGTTGCGCTTTGATTTAAAAGATGGCTTTCCGCTGTTAACGACCA
AAAAAGTGCACATGAAGTCGATTACTTATGAACTGTTTTGGTTTTTAAAAGGCGATACCCATGTCAAATATTTGCAAGAC
CATGGGGTACGTATTTGGAACGAATGGTCAACTGCGGAGCAAACCGCTCGCTTTGGTCGCCCTGAGGGTGAGCTGGGTCC
TATCTATGGTCATCAGTGGCGTAATTATGGGGCCACTAAAGCGGAGGACGGCCGCTACAATCAAGATGGGGTGGACCAAG
TTGTTGAGGTAATTGAGCAAATTAAGAGCAACCCCAATTCGCGTCGTTTGATTGTGTCCGGTTGGAACCCAGCCGAGGCG
ACCCAAGTGGCGCTACCGCCTTGCCATACATTATTTCAGTTCTTTGTGGCAGACGGCAAACTATCTTGCCAGCTGTATCA
GCGCTCCGCAGATTTGTTTTTAGGGGTGCCTTTTAACATTGCCAGCTACTCTTTATTAACACATATGATTGCTCAAGTTT
GTGACCTAGAGGTGGGTGAGTTTATTTGGACAGGTGGTGATTGTCACTTGTATCAAAACCATATTGATCAGGTCAATGAA
CAGCTGTCTCGCGAAGCTTATGAGTTACCTAAATTATGGCTCAACCCTGAAATCAAGGATATTTTTGATTTTACTTTTGA
TGATATCCGAGTTGAGGGCTATCAGTCGCATCCAGCGATTAAAGCACCCGTCGCGGTATAA

Protein sequence :
MITSKNEAAYLDLIRYVRDHGTEKGDRTGTGTRSHFGAQLRFDLKDGFPLLTTKKVHMKSITYELFWFLKGDTHVKYLQD
HGVRIWNEWSTAEQTARFGRPEGELGPIYGHQWRNYGATKAEDGRYNQDGVDQVVEVIEQIKSNPNSRRLIVSGWNPAEA
TQVALPPCHTLFQFFVADGKLSCQLYQRSADLFLGVPFNIASYSLLTHMIAQVCDLEVGEFIWTGGDCHLYQNHIDQVNE
QLSREAYELPKLWLNPEIKDIFDFTFDDIRVEGYQSHPAIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 9e-68 56
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 2e-60 48