Gene Information

Name : guaA (PsycPRwf_0015)
Accession : YP_001278925.1
Strain : Psychrobacter sp. PRwf-1
Genome accession: NC_009524
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 20646 - 22244 bp
Length : 1599 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGTATAGCCGCACCCACCATCAAAGAAGACCGCATTTTAATTATCGATTATGGCTCACAGTACAGCCAGCTGATTGC
CCGCCGTGTTCGTGAAGCGGGCGTATTCTGCGAAATGTACCCTTATGATATCGATACCAGTCGTATCGAAGCATTCGGTG
CCAAAGGGGTGATCTTATCAGGTGGCCCTGAAAGTGTGCACGACGAAAACAGCCCAAGAATCAATCAAGCTTTGTTTGAT
TTAAATGTGCCGATCTTAGGCATCTGCTACGGCATGCAGGCCATGGCCGATCACTTCGGTGGTAAGGTTCAGGCAAGTGA
TGTGCATGAATTTGGCGCGGCTACCATTGATGTGACGGGCCATAGTGCTTTACTTGATGGCATTGAAGATGAGCACAAAG
ACAACAGCCGCTTGCATGTGTGGATGAGCCACGGTGACAAAGTAGTTGAAGCCCCTAAAGGCTTTGATATCGTCGCCAGT
ACGCCAAGCTGCCCCATCGCCGTGATGGTCAATGAAGACAAAAAATACTATGGCCTACAATTCCATCCAGAGGTGACGCA
CACCTTACAAGGCGACGTGTTATTGTCTCGCTTTGTGCATCAAGTGTGTGGCTGCGCCGGTGACTGGACGCCAGATAACA
TCATCGATATGCGGGTTGAGCAATTAAAAGAGCAAATCGGTGATAAGCAAGTTCTACTTGGCCTATCAGGTGGTGTGGAC
AGCTCAGTTGTGGCGGCCTTATTACACAAAGCCATTGGCGATCAGCTGACTTGTGTGTTCGTGGATAATGGTCTACTGCG
TCTGCACGAAGGCGACCAAGTGATGCAAGTATTCGCCGAAAATATGGGCGTAAAAGTGGTGCGTGTCGATGCTGAAGATC
GCTTCTTAAGCGCATTAGCGGGTGAGAGTGAGCCGGAAGCTAAGCGTAAAATCATCGGCAAAACCTTTATCGATGTATTC
GCCGATGCCGCCCGTGATATCAGCCAAGGCAGCGACGGTAAGCCGGTTGAGTTCTTAGCGCAAGGTACCATTTACCCAGA
CGTGATTGAATCTGCCAAATCACACCAAGGTAAAGCGCACGTCATTAAGAGCCATCACAACGTAGGCGGCTTGCCCGATG
ATTTACAGTTTGAATTGGTTGAGCCATTACGTGATCTGTTCAAAGATGAAGTACGCAAACTGGGTATCGCCTTAGGCTTA
CCACACAAAATGATTTATCGTCATCCATTCCCAGGCCCAGGTCTAGGCGTACGCATCTTAGGCGAAGTCAAAAAAGAATA
CGCCGACATCCTGCGTCAAGCGGATGCTATCTTCATGCAAGAGCTTGAGCGCTCAGGCTGGTATGAGAAAACCGCGCAGG
CCTTTGCAGTATTTACCCCAGTGAAATCTGTCGGCGTGGTGGGTGATGGCCGCCGTTATGCGTGGGTTATCGCCCTACGT
GCGGTTGAAACCATCGACTTTATGACCGCCCGCTTTGCGCACTTGCCATACGAGCTGATCGAGACGGTGAGTAACCGCAT
CATGAACGAAATCAAAGATGTGTCTCGTGTGACTTATGATGTGTCGAGCAAGCCGCCGGCGACTATTGAGTGGGAATAA

Protein sequence :
MSIAAPTIKEDRILIIDYGSQYSQLIARRVREAGVFCEMYPYDIDTSRIEAFGAKGVILSGGPESVHDENSPRINQALFD
LNVPILGICYGMQAMADHFGGKVQASDVHEFGAATIDVTGHSALLDGIEDEHKDNSRLHVWMSHGDKVVEAPKGFDIVAS
TPSCPIAVMVNEDKKYYGLQFHPEVTHTLQGDVLLSRFVHQVCGCAGDWTPDNIIDMRVEQLKEQIGDKQVLLGLSGGVD
SSVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMQVFAENMGVKVVRVDAEDRFLSALAGESEPEAKRKIIGKTFIDVF
ADAARDISQGSDGKPVEFLAQGTIYPDVIESAKSHQGKAHVIKSHHNVGGLPDDLQFELVEPLRDLFKDEVRKLGIALGL
PHKMIYRHPFPGPGLGVRILGEVKKEYADILRQADAIFMQELERSGWYEKTAQAFAVFTPVKSVGVVGDGRRYAWVIALR
AVETIDFMTARFAHLPYELIETVSNRIMNEIKDVSRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-134 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-134 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-134 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-115 48