Gene Information

Name : lysS (RoseRS_0078)
Accession : YP_001274469.1
Strain : Roseiflexus sp. RS-1
Genome accession: NC_009523
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 92787 - 94256 bp
Length : 1470 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGGAACTCAACGAACTTCAACAACAGCGCCTGGCAAAACTGGAACGCTTGCGCGCAGCCGGCATCGACCCGTATCCGCC
GCGTACCCGGCGCACCCATACGATTGGCTTCGTGCTTGCCAGTTTCGACCAGTTGATGGAACGCGGAGAACAGGTCACCG
TCGCCGGGAGAATTGTGGGCGCCCGTCGGATTCTGGGCAAACTGGCATTTGCCCACATCGAAGACGAGTCGGGCCGCATC
CAGATCTGGCTCAGTCGCGGCGACATCGGCGACGAATGGTTCGACCGGTTTCGCGATGACCTCGATACGTTCGACATTGT
CGAAGCCACGGGAACGTTGCGCCGCACGCAACGCGGCGAGCCTTCGGTGTTCGTCGAGCGCCTGGGGGTGCTGGCAAAAT
CGCTCAACCCGCCGCCGGAAAAGTGGCATGGTCTTTCGGACATCGAAGAGCGTCATCGTCAACGCTACCTCGACCTGATC
GTCAACCCTGAAGTGCGCGACGTGTTTCGCACACGCGCGAAGATCGTCAGCACAATGCGGCGCTTCCTTGACGAACGCGG
CTTTCTTGAGGTGGAGACGCCAACCCTGCAACCGATCTACGGCGGCGCTTCGGCCCGCCCGTTCATCACGCACCATAACC
AGTTGAAGCAGGATCTCTATCTGCGCATCGCCGTCGAACTCTACCTGAAGCGCCTGATCGTCGGCGGCTTTGAGCGCGTC
TATGAGATCAGCAAGGTTTTTCGCAACGAAGGGGTTGATCGTACCCACAACCCTGAGTTCACGATGATGGAATGTTACCA
GGCGTATGCCGATTACAACGATATGATGCGCCTGGTCGAAGACCTGTACCGGACCCTGGCGCTGGAAGTCGCTGGCAGCA
CAACCATTGTCTTTCAGGGACACACTATCGATTTCGGTCCTGCGTGGCAGCGTGTTTCGATCCCGACGGCGATTGCCGCG
CGCACCGGCATCGACATTCTCGAACTCACCGAACTCGAACCGTTGCAACGAGCGATCCGCGCAGTCGGGCTGAAGGTCGA
TCTCAAACCCAGTTGGGGCAAACAGGTTGACGAGATCTTTAGCGTTTATGTGCAACCAGAATTGATCCAGCCAACGTTCG
TTATCGATCATCCGGTGGCGCTGTCGCCGCTGGCGAAACGTCGTCCCGATCAACCGCTGCTGGTGGAACGCTTCGAGCCA
ATCGTGGCTGGCATGGAAGTCGGCAATGCGTTTACCGAATTGAACGATCCGCTCGACCAGGAGCAGCGTTTTCTGGAACA
GGGGCGCGCGTATGATGCTGGCGACGATGAAGCGCAACAGATGGACATTGACTTCCTCAATGCGCTGATGTATGGTATGC
CGCCAACCGGCGGGTTAGGCATCGGTATCGACCGGACGGTGATGCTGTTCACCGATCAACCGAGCATCCGCGAAGTCATC
CTGTTCCCGCACATGCGTCCGCGTGATTGA

Protein sequence :
MELNELQQQRLAKLERLRAAGIDPYPPRTRRTHTIGFVLASFDQLMERGEQVTVAGRIVGARRILGKLAFAHIEDESGRI
QIWLSRGDIGDEWFDRFRDDLDTFDIVEATGTLRRTQRGEPSVFVERLGVLAKSLNPPPEKWHGLSDIEERHRQRYLDLI
VNPEVRDVFRTRAKIVSTMRRFLDERGFLEVETPTLQPIYGGASARPFITHHNQLKQDLYLRIAVELYLKRLIVGGFERV
YEISKVFRNEGVDRTHNPEFTMMECYQAYADYNDMMRLVEDLYRTLALEVAGSTTIVFQGHTIDFGPAWQRVSIPTAIAA
RTGIDILELTELEPLQRAIRAVGLKVDLKPSWGKQVDEIFSVYVQPELIQPTFVIDHPVALSPLAKRRPDQPLLVERFEP
IVAGMEVGNAFTELNDPLDQEQRFLEQGRAYDAGDDEAQQMDIDFLNALMYGMPPTGGLGIGIDRTVMLFTDQPSIREVI
LFPHMRPRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-101 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001274469.1 lysyl-tRNA synthetase VFG1668 Protein 9e-102 48