Gene Information

Name : RoseRS_0463 (RoseRS_0463)
Accession : YP_001274838.1
Strain : Roseiflexus sp. RS-1
Genome accession: NC_009523
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 588748 - 590922 bp
Length : 2175 bp
Strand : -
Note : TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein

DNA sequence :
ATGTCAACCCAAGAACTCATCACCCAACTTCGCACCCGCCCTGGGGTGCTTGCCGTTCATTACGACGAGCAGGAACGTGT
GTTGACCTTGCGGTATGACGGCGGTCGCGTCAATGTAGCAGATATCGAGGCGCTCGCCCGCAGCGCCGGTGCGACGCTGC
GCATGCTGCCCGCCGAAACCCGCCCGTTGACGCCGGAAGAGGCGGAACTGGCGGCGTTGCCCTGGATGATCCGCCTGACC
ACGCTGACCCTGGTGATGGTCATTGTCGGCTGGGTCGTCGAGGATTTCACGACGCTGCCACGATGGGTCGCCTGGCTGTC
GTATGCCGTTGCGTATGCCAGCGGCGGGTTCTACAGCATCCAGGAGGCCTGGGAAACGCTGCGCAAGCGTCAGTTCGATG
TCAACTTTTTGATGATTGTTGCAGCGGTTGGCGCCGCGATTGTCGGGCAACCCCGCGAGGGCGCTATTCTGATGTTCCTG
TTTTCGCTCTCTGGTACGCTCGAAACATATGCGATGGGGCGCACCCACGCTTCCATCCGTGCACTGCTCGATATGACGCC
GAAAGAAGCGGAGGTGTACCGCGATGGAACTCTCGTTCGCGTGCCGGTCGAGGAGGTGCAGGTCGGCGAGATTGTGCTGG
TGCGCCCCGGTGCGCAGGTCCCCGCTGATGGCGTGGTTGTGCGCGGCGAGTCGGCGCTGAACGAAGCGTCGATCACCGGC
GAGTCGATGCCGGTTGAGAAACGACCCGGTGCGAAGGTGTTTGCCGGGACGATCAACGGGCAGGGCGCACTTGAGGTGCG
CGTAACGACTTCCGTCGAAAACTCGACGCTGGCGCGGATCGTGCAGGTGGTGCGCGAGGCGCGTGAACAGAAGGCGAAGA
GTCAGGATTTCACCGACCGGGTGATCGGTCAGTACTATGCCTATGCGGTGGTCGGGCTGACGCTGCTGGCGATCATTGTT
CCGCTGCTGTTCCTGGGATGGGATCTGAAGACAACCCTCTACCGTGCGATGACGTTGATGGTCGTGGCGTCGCCGTGCGC
CCTGGTCATTTCAATCCCGGCGGCGCTCCTCTCTGCGCTTGCTTCCGCAGCCCGCGGCGGCGTTCTGTTCAAAGGCGGGC
GGCACCTGGAAGCAGCAGCGCAGGTGCGGGTCGTGGCGTTCGACAAAACCGGCACCCTCACCACCGGACGCCCTGGCGTC
GTGGCGGTCATTCCGGTCGATGGCGCCCCTGCCAGCCTGGAAGAGGCGTTTATCGGCGTCGATGCACCAGAACATCCGGC
GCAAGCGATCCCTGATGACCAGATCGGACCGTTGACACCCGAACAGCGCTGGTTGCTGGCGCTGGCAGCCGCCATCGAAC
GCCCGTCGGAGCACCCGCTGGCGCGGGCTATTGTGCGCGGCGCCGATGAGCGCGGTCTGCCGGTGATCGAGGCGTCGGGC
TTCGAGGCGTTGACCGGCGCCGGCGCGGCGGCAACCATCCACGGGCAGCGCCTGACGATTGGACGCCCGATGCTGTTCGA
CCTGTCGCCAGACCTGATGGAGCAGATCGCTACACAGCAGGAACTGGGGCGAACGGTCGTGGCGTTGGGAAGCGGGCGCA
CAGTGTGGGGCATCATTGCAATCGCCGACACAGTGCGCCCCGAAGCAGCGGCGGCAGTCGCCCGGTTGAAGCGCACCGGC
ATCGAGCGGGTGGTGCTGCTGACCGGCGACAATCATCAGGTGGCGCAGGCGATCGGGCAGGCGCTCGGTGTGGACGAGGT
GCACGCTGAGTTGCTCCCGGAGCAGAAAGTCGCCGTGCTGCGCGAACTTGAGCAACGCTACGGACCGGTCGCCATGATCG
GCGATGGCGTCAATGACGCGCCTGCGCTGGCAAGCGCGACGCTCGGCGTGGCTATGGGCGCTGCCGGGACCGATGTGGCG
CTGGAGAGCGCCGACATGCTGTTGATGAGCGACGATCTGAGTCGTCTGCCGGGGGCATTGCGGCTGGCGCGGCGCGCGCG
GGCCATCGTGCGCCAGAACCTGGCATTCGCTTTTACCGTGATAGCGGTGCTGATGGTCTTCGCCATGTTCGGCGCCATTC
CTCTGACCCTTGGCGTTATCGGGCACGAGGGGAGCACACTGATCGTCGTGGCGAATGGTCTGCGGTTGCTGGCGGAACGA
ATTCAACACGGATGA

Protein sequence :
MSTQELITQLRTRPGVLAVHYDEQERVLTLRYDGGRVNVADIEALARSAGATLRMLPAETRPLTPEEAELAALPWMIRLT
TLTLVMVIVGWVVEDFTTLPRWVAWLSYAVAYASGGFYSIQEAWETLRKRQFDVNFLMIVAAVGAAIVGQPREGAILMFL
FSLSGTLETYAMGRTHASIRALLDMTPKEAEVYRDGTLVRVPVEEVQVGEIVLVRPGAQVPADGVVVRGESALNEASITG
ESMPVEKRPGAKVFAGTINGQGALEVRVTTSVENSTLARIVQVVREAREQKAKSQDFTDRVIGQYYAYAVVGLTLLAIIV
PLLFLGWDLKTTLYRAMTLMVVASPCALVISIPAALLSALASAARGGVLFKGGRHLEAAAQVRVVAFDKTGTLTTGRPGV
VAVIPVDGAPASLEEAFIGVDAPEHPAQAIPDDQIGPLTPEQRWLLALAAAIERPSEHPLARAIVRGADERGLPVIEASG
FEALTGAGAAATIHGQRLTIGRPMLFDLSPDLMEQIATQQELGRTVVALGSGRTVWGIIAIADTVRPEAAAAVARLKRTG
IERVVLLTGDNHQVAQAIGQALGVDEVHAELLPEQKVAVLRELEQRYGPVAMIGDGVNDAPALASATLGVAMGAAGTDVA
LESADMLLMSDDLSRLPGALRLARRARAIVRQNLAFAFTVIAVLMVFAMFGAIPLTLGVIGHEGSTLIVVANGLRLLAER
IQHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-87 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
RoseRS_0463 YP_001274838.1 heavy metal translocating P-type ATPase BAC0092 Protein 2e-99 45
RoseRS_0463 YP_001274838.1 heavy metal translocating P-type ATPase BAC0124 Protein 2e-84 44
RoseRS_0463 YP_001274838.1 heavy metal translocating P-type ATPase BAC0099 Protein 3e-83 42
RoseRS_0463 YP_001274838.1 heavy metal translocating P-type ATPase BAC0100 Protein 3e-60 41