Gene Information

Name : RoseRS_3466 (RoseRS_3466)
Accession : YP_001277774.1
Strain : Roseiflexus sp. RS-1
Genome accession: NC_009523
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 4345391 - 4346665 bp
Length : 1275 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGACATTCGACTGATCCGTGAGCAACCCGATCTGGTTAAAGCGTCGCTCGGGCGAACCGGCGTCGATCCGGCGCA
GGTCGATGCGGTGCTGGCATACGACGAGCAACGCCGCGCGCTGCTGCGTGAGGTGGAACAACTCAAAGCGTTGCGGAATG
CAGTCTCGAAAGAGATCGGCAAAATGAGCGATGCGGCCGCACGCGACGCGAAGATCGCCGAAATGCGCGCCGTCGGTGAT
CGCATTGCCGAACTGGACCGCGAACTTGCAGCGGTCGAAGAACAGCAGTACGCTGCGCTCATGGAACTGCGCAACCTGCC
GCACCCCTCGGTTCCCGACGGACCCGACGAGACGTACAACGTGGTGATTGCGCAGGAAGGCGAACCGCGCACCTTCGATT
TCACCCCCAAACCGCACTGGGAACTGGGTGAGGCGCTCGACATCATCGACTTCGAGCGGGGCGTCAAACTGTCGGGATCG
CGCTTCTACGTGCTCAAAGGACCGGGCGCCCGCCTGCAACGCGCTCTCATCCAGTGGATGCTCGACCTGCACGGCAAACA
GGGATACGACGAGGTCTACACGCCGTTTGTGGTCAAAGAGCAGTGTATGTGGGGCGCACGTCAACTGCCCAAGTTCCGCG
ACAACCTCTACCGTGACGTGGAAGATGACCTGTGGCTGGTGCCAACTGCCGAGGTGCCGGTGACCAATCTGCACCGCGAT
GAAATCCTGGACGCCGACCAGTTGCCATTGCGCTATTGCGCGTACACCCCCTGCTTCCGTCGTGAGAAGATGAGCGCCGG
GCGCGACGTGCGCGGTATCAAGCGCGGGCATCAGTTCGACAAGGTCGAAATGTACATGTTCGTTCGCCCGGAGACCAGTT
ACGATGAACTCGAAAAACTGCGCGCCGACGCCGAGGAAACCTGTCGCCTGCTGGGATTGCCCTTCCGCACCAAGGAACTC
TGCACCGGCGACCTGGGGTTTGCCGCCACACGCACCTACGACATCGAAGTCTGGGCGCCGGGCCAGGGCGAGTGGCTCGA
GGTCAGTTCCTGTTCAAACGTCGAAGCCTTTCAGGCGCGTGCAGCGAATATCCGCTACCGTCCGGAACCCGGCGCGCGCC
CCGAGTATGTTCACACGCTGAATGGCTCAGGATTGGGCTTGCCGCGCACCCTCATCGCCATTCTCGAAAACTATCAGCAG
GCGGACGGCAGCGTTGTCATCCCCGAGGTGCTGCGCCCGTACATGGGCGGTATCGAAGTCATTCGCCGGACATGA

Protein sequence :
MLDIRLIREQPDLVKASLGRTGVDPAQVDAVLAYDEQRRALLREVEQLKALRNAVSKEIGKMSDAAARDAKIAEMRAVGD
RIAELDRELAAVEEQQYAALMELRNLPHPSVPDGPDETYNVVIAQEGEPRTFDFTPKPHWELGEALDIIDFERGVKLSGS
RFYVLKGPGARLQRALIQWMLDLHGKQGYDEVYTPFVVKEQCMWGARQLPKFRDNLYRDVEDDLWLVPTAEVPVTNLHRD
EILDADQLPLRYCAYTPCFRREKMSAGRDVRGIKRGHQFDKVEMYMFVRPETSYDELEKLRADAEETCRLLGLPFRTKEL
CTGDLGFAATRTYDIEVWAPGQGEWLEVSSCSNVEAFQARAANIRYRPEPGARPEYVHTLNGSGLGLPRTLIAILENYQQ
ADGSVVIPEVLRPYMGGIEVIRRT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-98 52