Gene Information

Name : RoseRS_0281 (RoseRS_0281)
Accession : YP_001274663.1
Strain : Roseiflexus sp. RS-1
Genome accession: NC_009523
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 356471 - 359557 bp
Length : 3087 bp
Strand : +
Note : TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction enzyme, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like

DNA sequence :
ATGATGAGTGAGCGTCACTTCTGTGAATCCACCATCGAATCCGCTGCCCTCGCCCGGCTAGAAGCTTCTGGCTGGCAGGT
TGCGCACGGTCCCGACCTCGCCCCGGGCACGCGGACAGCTGAGCGGCGCGACTATGGCGAAGTGGTGCTGACCGGTCGGC
TCCGCGACGCGCTTGCCCGCCTCAACCCCGACCTGCCTGTCGAGGCGCTGGACGACGCCTTCCGCCAGCTCACGCAGCCC
CAGGGCGCCGATCTGATCCAGCGCAACCGCGCGCAGCACCGCCTGCTGGTGGACGGGGTGACGGTCGAGCACCGCAATGC
CGGGGGCGCGATCTGCGGGGCGCAAGCCAGGGTGATTGACTTCGACGACCCGGCGAACAACGACTGGCTCGCAGTCAATC
AGTTCACGGTGGTGGAAAACAAGCACACGCGCCGTCCAGACATAGTGCTGTTCGTCAACGGCCTGCCGCTGGCAGTGCTG
GAGCTGAAGAACGCCGCCGATGAAAAGGCGACGATCTGGACGGCCTGGCAACAACTCCAGACCTATCAGGCTCAGATCCC
CTCGTTGCTGGCTACCAACGCCGCACTCGTCATCTCCGACGGCCTGACAGCGCGCGTCGGCGCGCTCGGTGCGGGGCGCG
AGTGGTTCAAGCCGTGGCGCACCATTCACGGCGAGGCGCTGGCGGATCCCCATATGCCCGAATTGCAGGTGGTGATCGAG
GGACTCTTCGCGCCGCGCCGTTTCCTCGACTTCGTCCGTGACTTCATCGTCTTCGAGGACGATGGCAGCGGACGGCTGAT
CAAGAAGATGGCCGGGTACCACCAGTTCCATGCGGTGCAGGTGGCAGTCGCCGAAACGCTGCGCGCCGCCGAACTGGCGC
GCACTGATCAGGTGGCGGAGGAGCGTGGGCGCTATGAGGCGGGACGCAGGCCCGGGGGCAAGCCTGGAGATCGGCGTATC
GGCGTGGTGTGGCACACGCAGGGTTCGGGGAAGAGCCTGACCATGGTGTTCTATGCTGGCCGTATCGTCCGCGAGCCGGC
AATGGAGAACCCGACGATTGTCGTGCTCACCGACCGCAACGACCTCGACGACCAGCTCTTCGCCACCTTCGCGCGCTGCC
GCGACCTGCTGCGCCAGCCGCCGGTGCAGGCCGAGAGTCGCGTCCACCTGCGCCAGATTCTGTCTGTAGCAGCGGGCGGC
GTGGTGTTCACCACGATTCATAAGTTCTTCCCGGAAGAGAAAGGCGACCGCCACCCGACGCTCTCCGAGCGGCGTAATAT
CGTGGTGATCGCCGATGAGGCGCACCGCAGCCAGTACGACTTCATTGACGGCTTCGCGCGCCACATGCGCGACGCCCTGC
CGAACGCTTCGTTCATCGGCTTTACCGGCACGCCGATTGAAAAGACCGACGCCAACACCCGCGCGGTCTTCGGCGATTAC
ATCAGCATTTACGACATCCAGCGCGCCGTCGAGGATGGCGTGACCGTGCCGATCTACTACGAGAGTCGCCTGGCGAAGCT
TGCCCTCGACGAGACGGAGCGACCGAAGATCGACCCGGACTTCGAGGAGGTCACCGAAGGCGAGGAGGTCGAGCGCAAGG
AGAGGCTCAAGAGTAAGTGGGCGCAGTTCGAGGCCATCGTCGGCGCGGAGAAACGGCTCAGGCTGGTGGCGCGCGACATC
GTCGAGCATTTCGAGAAGCGGCTGGAGGCACTGGACGGAAAGGCGATGATCGTCTGTATGAGCCGACGTATCTGCGTCGA
GCTGTATCGGGAGATTGCCCAATTGCGGCCGCAGTGGGCAGCCGATGACGACGAGCGGGGCGCGATGAAGGTGGTGATGA
CCGGCTCGGCCTCCGACCCGCTCGACTGGCAACCTCACATCCGCAACAAACCGCGACGCGAGGCGCTTGCCAACCGTTTT
CGCAATCCAGGCGATCCGTTCAGGCTCGTGATTGTGCGCGACATGTGGCTGACCGGCTTTGACGCGCCCAGCCTGCACAC
GATGTACATCGACAAGCCGATGCGCGGCCACGGTCTGATGCAGGCCATTGCGCGCGTCAACCGCGTCTTCCATGACAAGC
CCGGCGGCCTGGTGGTGGACTACCTGGGGCTGGCGCACGAACTCAAGGCTGCGCTCGCCACCTATACCGAGAGCGGCGGT
ACCGGCCAGACGACCGTCGATCAACAAGAGGCCATAGCACTGATGCAGGAAAAGTACGAGATCTGCTGTGGCATCCTGCA
CGGCTTCGACTGGTCGGATTGGATAAGCGGCGACCCGCAAGCGCGTATCGGTCTGTTGCCCGCAGCGCAGGAGCAGGTGC
TGTCGCGCGTGAACGGCAAGGAGCGGTTCATCCAGGCGGTACGCGACCTGACCAGGGCGTTCGCGCTCGCGACGCTGCAC
GAGGAGGCAATCAAGATCCGCGACGATGTCGCCTTTTTCCAGGCGGTGCAGGCAGCGCTGACCAAACGCGCACCCGGCGA
GATGCGTCCGGAGGATGAGCTGGATCACGCCGTCCGCCAGATCATCGCTCGCGCAGTCGCTCCTGCAGGCGTTATAGATA
TCTTCACGGCAGCCGGGCTTCAGAAGCCCGACATCTCGATTCTCTCCAACGAATTCCTGGCCGAGGTGCGCGGCATGCCA
CAGCGAAACCTGGCGGTAGAAACGCTACAGAAACTGCTCAAGGGGGAGATCAGTACGCGCCAGCGAAAAAATGTCGTCCA
GGCGCGCTCCTTCGCCGAGATGCTGGAGCAAACCATCCGCCGCTACCAGAACCGCGCCATCGAGGCGGCGCAGGTGATCG
AGGAGCTTATCTCCCTGGCCAGGGACATGCGCGAGGCCGATGCGCGTGGCAAGAAGCTGGGACTCTCCGAGGAGGAACTG
GCTTTCTACGACGCTTTGGAGACCAACGATAGCGCGGTGAAGGTGCTGGGAGACGAGACATTGAGGACGATCGCGCGCGA
ATTGGTCAAGACCGTGCGGAGCAACGTCACTATCGACTGGACAATCCGTGAGAACGTCCGGGCGCAACTGCGCGTGTTGG
TGAAGCGCATTCTGCGCAAGTACGGCTACCCCCCCGACAGGCAGTAG

Protein sequence :
MMSERHFCESTIESAALARLEASGWQVAHGPDLAPGTRTAERRDYGEVVLTGRLRDALARLNPDLPVEALDDAFRQLTQP
QGADLIQRNRAQHRLLVDGVTVEHRNAGGAICGAQARVIDFDDPANNDWLAVNQFTVVENKHTRRPDIVLFVNGLPLAVL
ELKNAADEKATIWTAWQQLQTYQAQIPSLLATNAALVISDGLTARVGALGAGREWFKPWRTIHGEALADPHMPELQVVIE
GLFAPRRFLDFVRDFIVFEDDGSGRLIKKMAGYHQFHAVQVAVAETLRAAELARTDQVAEERGRYEAGRRPGGKPGDRRI
GVVWHTQGSGKSLTMVFYAGRIVREPAMENPTIVVLTDRNDLDDQLFATFARCRDLLRQPPVQAESRVHLRQILSVAAGG
VVFTTIHKFFPEEKGDRHPTLSERRNIVVIADEAHRSQYDFIDGFARHMRDALPNASFIGFTGTPIEKTDANTRAVFGDY
ISIYDIQRAVEDGVTVPIYYESRLAKLALDETERPKIDPDFEEVTEGEEVERKERLKSKWAQFEAIVGAEKRLRLVARDI
VEHFEKRLEALDGKAMIVCMSRRICVELYREIAQLRPQWAADDDERGAMKVVMTGSASDPLDWQPHIRNKPRREALANRF
RNPGDPFRLVIVRDMWLTGFDAPSLHTMYIDKPMRGHGLMQAIARVNRVFHDKPGGLVVDYLGLAHELKAALATYTESGG
TGQTTVDQQEAIALMQEKYEICCGILHGFDWSDWISGDPQARIGLLPAAQEQVLSRVNGKERFIQAVRDLTRAFALATLH
EEAIKIRDDVAFFQAVQAALTKRAPGEMRPEDELDHAVRQIIARAVAPAGVIDIFTAAGLQKPDISILSNEFLAEVRGMP
QRNLAVETLQKLLKGEISTRQRKNVVQARSFAEMLEQTIRRYQNRAIEAAQVIEELISLARDMREADARGKKLGLSEEEL
AFYDALETNDSAVKVLGDETLRTIARELVKTVRSNVTIDWTIRENVRAQLRVLVKRILRKYGYPPDRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 49
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 45
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 45
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 45