Gene Information

Name : hemC (RoseRS_1750)
Accession : YP_001276090.1
Strain : Roseiflexus sp. RS-1
Genome accession: NC_009523
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2162785 - 2163696 bp
Length : 912 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAAACAGACTCTGATTATCGGCACGCGCGCCAGTAAACTTGCACTGGTGCAGACGTATATGGTCCGCGACGCCTTGCA
GTCGGCGCATCCCGGATTGACGGTCGCTGTCGAGCATATTACAACACGCGGCGACATCATTCTTGATCGTCCACTCAATG
CGATTGGCGACAAGGGGTTGTTCGTCGTCGAGATCGAGGAAGCGATGCGTGCCGGCAGAATCGATCTGGCAGTTCACAGC
GCCAAAGATCTGCCATCGGTGTTGCCGCCCGATATGACGCTTGCGGCATGCCCGCGACGCGCCGATCCGCGCGATGCGCT
GGTGGCGCAACCGGGTATGACGCTGGCTGCCCTCCCTTCCGGCGCGCGTGTCGGAACCAGCAGCCTGCGGCGCGCCTGTC
AGTTGCGCGCCCTGCGACCCGATCTCACGCTGGTCGATCTGCGCGGGAATGTTGATACACGGTTGCGAAAGTTGCGTGAA
GGGCAGTACGATGCGATTGTGCTTGCCGCAGCCGGCTTGAAGCGCCTTGGTCTCGACGGTGCGATCTCCGAGTTGATCGA
ACCGGACGTGCTGATTCCGGCGGTGGGGCAGGGGGTGATCGGCGTCGAGGCGCGCGCCGACGATGAGGAGGTGCTCCGCC
TCCTTGCACCGCTGGACGATCAGGCGGCGCGCATCGCCATTACCGCCGAACGCGCATTTCTGGCGCGCATTGGCGGCGGC
TGTCAGGTGCCGGTCGGAGCGCTGGCGCATCTCGAAGGCGATGAATTGCTGCTGCGCGGGATGATCGGCGCGCGCGACGG
GCGGATGGTGCGCGGGATGCAGCGTGGCTCAGCGTCCGATCCGGTTGGTCTGGGTTGTGCGCTGGCGGACGAGTTGCTCG
ACCAGGGCGGGCGGGCATTGCTTGCAGGATAA

Protein sequence : 
MKQTLIIGTRASKLALVQTYMVRDALQSAHPGLTVAVEHITTRGDIILDRPLNAIGDKGLFVVEIEEAMRAGRIDLAVHS
AKDLPSVLPPDMTLAACPRRADPRDALVAQPGMTLAALPSGARVGTSSLRRACQLRALRPDLTLVDLRGNVDTRLRKLRE
GQYDAIVLAAAGLKRLGLDGAISELIEPDVLIPAVGQGVIGVEARADDEEVLRLLAPLDDQAARIAITAERAFLARIGGG
CQVPVGALAHLEGDELLLRGMIGARDGRMVRGMQRGSASDPVGLGCALADELLDQGGRALLAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-57 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-57 52