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Name : Lreu_0874 (Lreu_0874) Accession : YP_001271474.1 Strain : Lactobacillus reuteri DSM 20016 Genome accession: NC_009513 Putative virulence/resistance : Unknown Product : HsdR family type I site-specific deoxyribonuclease Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 924309 - 927434 bp Length : 3126 bp Strand : + Note : TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: type III restriction protein, res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases-like DNA sequence : GTGGCAAGTTATCTTAACGAAGAAAATATAGAGGGCATTGCTTTAAGATGTCTTGATGAAGTAGGCTATCAAGTCTACAA AAGTGCTAGTTATACTAGTCCGAATGTAGAAATAGATGCTGAAAGAAATAATGACCATACACAACCTATTTTAAAAGGAC AATTAGAAAACGCTTTACGCAAGTTAAATTCTGGACTTGATGATGAAGTATACCGTAATGCCATTCATCAATTTGAAATG CTAGCAGATAGCCCAGATATGATGCTTAATAACCATAAACTTCATGAATTAATTATCGGCGGAGCAAAAGTAAAAACATC AATTAAAGGTGAGGACCGGACCATTACTTTGTATCCGATTGATTTTAAAAACGTTGATAACAATACATTTATTGCAACAA ATCAATTTACAATGAAACAAGGAGAACATGAAAGAAGACCAGACATTACTCTTTTTATTAATGGGCTTCCTTTAGTTACC TTTGAATTAAAGAACCCAGCAAATGCGAATGTAGGTATTCAACAAGCTTTTGCCCAATTTTCTACTTATAAAGAAGAAAT ATCTTCTTATATGCAATATAACGAAATTTTAATTGTTTCTGATGGAATTAATGCGCGAGCTGGGTCATTAACAGCGGGAA TTGATCGCTTTATGCGGTGGCGCGAGCCGAAAAATGTAGATATTGACGATTCAATGATGGAATTAGAAGTATTGATAAAA TACATGCTTACCCCATCTGATTTATTAAACATCATTCAGAATTTTATTCTTTTTGAAAGTGATGGAGACAAGACAATCAA GATTTTAGCAGCATATCATCAATACTATATGGTTAATAAAGCTGTAAAAAGAACATCAAAAGTATTGGCTGACCCTGATG ACAAACGAATTGGTGTTGTTTGGCATACCACTGGTTCTGGTAAATCATTGTCGATGGTCTTTTATTCTGGAATAGTAGCT CGTAAACTTGGTAATCCAACTATTTTAGTAATTAATGATCGTAATGATTTAGATGATCAGTTATTTGGTACTTTTGCGGC TGCTCATGAATATCTACAACAAAACCCTGATCACGCTGAATCACGAGGAGAAGTTCGTAAATACATGAGTAAGAATTCTG GCGGGATTGTTTTTAGTACAATTCAAAAATTCTCACCAAACTTTGACGCAGGTGAAGAACATATGCCTATACTTACAAAC CGTTCTAACGTTATCGTAATGGTTGATGAAGCTCATCGGTCTCAATATGGAATGCAAGCAAAACTAACCGATAATGGTAT TCGTTATGGATATGCTAAATATTTGCGTGAGGCTCTTCCTAACGCCTCGTTTATTGGTTTTACAGGAACACCAATAAATA CTGAAGATAAATCTACCGTGGCAATGTTTGGAAATTACATTGATGTTTATGATATTACTCAAGCAGTTAATGATCATGCC ACGGTCCGGATTTATTATGAAAGTCACGTTTTCCCATTAAAGCTTAAGGACAATGCAATTGATGAATATCAAAAGTTAAT TAAAGAAGCTGGTATTAATGACGATCCTAATCTTAGAGAAACTGAGCGACGGAATCGGGCATTTACTAGATTAGAGGCCC TTGCCGGTGCAAAACCACGGTTAGAAAAAATAGCCCAACACTTTGTTCATCATTTTGAATCACGACAAAAGGAAGAATTT GGTAAGTCGATGATTGTTGAAATGTCACGACAAAATGCAGTAAAGCTATATAATGAAATTGCAAAATTACGTCCTGAGTG GATAAATGATGATATTCATAAGGGAAAAATCAAAGTTATTATGACGTCTAATGCTTCTGATGGCCCAGAATTTGCTAAAT TTAAGACAAGCAAACAAGACCGATTTACGTTACAACAACGGATGAAAGATAACGATGACGAATTACAAATTGTAATAGTT GTTGATATGTGGCTAACTGGATTTGATGTTCCTAGCATGAATACCATGTACATTGACAAGCCAATGCAAGGACATAATCT TATCCAGGCAATTGCTCGTGTTAATCGAGTATTTAAGAATAAAGATAGTGGGTTAATTGTCGATTACATTGGGATTGCTG ATGCTCTTCGTTTTGCCTTAAATGTATACACAAAAGATGACCAAGGAAAAGTTGGAATTAATGTTGATCGTGCACTAATG CTTCTAAAAGAGAAATATGACATTATTAAAGAAGATTTCCTATATGGGATTGATTACTCAGAATTTGATTCTGATGATAG CCAAACTCGTCAGAAGGCAGTTACTCGTGTTGTAAATGAATTAGCTGCAGAGGACGATGAAACAAAACAAAAATTCTTTG ATGTAGTAACAGAACTTCAAAAAGCTTATGCATTAGTTTCAACACAGCCGGAAGCCCAAGATTTAAGTGCGGAGATAGCA TTCTTTAAAACGGTTAAAGTATTCTTAACTAAGCTTGAGGCTCCTGACGATCCAGATGATAGTAAAGAGATTCATAGTTC TGTTGATTATCGAATGCAACAACTATTAGATCAATCAATTATTTCAGAGCCGAACGTTGACATTTATCGTGACCTAGGAT TAGAACGCCCTAACTTAGATTTAATCTCAGAACAATTTCTTGAAAAAGTAAATGAAATTACTGAGAAAGATCTAGCAATT ACTCTTTTAGAGAAACTATTAAAAGGGCAAGTAAAAGCCTACCAAAAAACGAATATTGTTAAAGGCAAGAAGTTTGAGGA ATTACTTCAAGAGTCAATTGATGATTACAATAGGCGGGGAATTACCAGTGAAATTGTAATTAGAAAGTTAATTGATATGG CTAAGGAAATTAATAAAGAACAACAAGAAGGTAAGAATCTGGGACTTTCAAAAGAAGAAGTTGCCTTTTATGATGCTTTA GCTGATCATGAGAAAGCTGTTCAAGAATTAGGAGAAGAAAAGTTACATCTTATTGCTGCTGAATTAGTAAAGACTGTAAA GCAACAATCAGGGGTTGATTGGGAGCGGCGCAGCAATGTTCGTGCTAAAATGCGTGTTGCAGTTAAACATCTATTACGTA AGTATGGTTATCCACCTGATATTGCTCCAGATGCCATTAAGACCGTAGTAAAGCAAGCTGAACAAATGGCTTCTCAAGAG AGCTAA Protein sequence : MASYLNEENIEGIALRCLDEVGYQVYKSASYTSPNVEIDAERNNDHTQPILKGQLENALRKLNSGLDDEVYRNAIHQFEM LADSPDMMLNNHKLHELIIGGAKVKTSIKGEDRTITLYPIDFKNVDNNTFIATNQFTMKQGEHERRPDITLFINGLPLVT FELKNPANANVGIQQAFAQFSTYKEEISSYMQYNEILIVSDGINARAGSLTAGIDRFMRWREPKNVDIDDSMMELEVLIK YMLTPSDLLNIIQNFILFESDGDKTIKILAAYHQYYMVNKAVKRTSKVLADPDDKRIGVVWHTTGSGKSLSMVFYSGIVA RKLGNPTILVINDRNDLDDQLFGTFAAAHEYLQQNPDHAESRGEVRKYMSKNSGGIVFSTIQKFSPNFDAGEEHMPILTN RSNVIVMVDEAHRSQYGMQAKLTDNGIRYGYAKYLREALPNASFIGFTGTPINTEDKSTVAMFGNYIDVYDITQAVNDHA TVRIYYESHVFPLKLKDNAIDEYQKLIKEAGINDDPNLRETERRNRAFTRLEALAGAKPRLEKIAQHFVHHFESRQKEEF GKSMIVEMSRQNAVKLYNEIAKLRPEWINDDIHKGKIKVIMTSNASDGPEFAKFKTSKQDRFTLQQRMKDNDDELQIVIV VDMWLTGFDVPSMNTMYIDKPMQGHNLIQAIARVNRVFKNKDSGLIVDYIGIADALRFALNVYTKDDQGKVGINVDRALM LLKEKYDIIKEDFLYGIDYSEFDSDDSQTRQKAVTRVVNELAAEDDETKQKFFDVVTELQKAYALVSTQPEAQDLSAEIA FFKTVKVFLTKLEAPDDPDDSKEIHSSVDYRMQQLLDQSIISEPNVDIYRDLGLERPNLDLISEQFLEKVNEITEKDLAI TLLEKLLKGQVKAYQKTNIVKGKKFEELLQESIDDYNRRGITSEIVIRKLIDMAKEINKEQQEGKNLGLSKEEVAFYDAL ADHEKAVQELGEEKLHLIAAELVKTVKQQSGVDWERRSNVRAKMRVAVKHLLRKYGYPPDIAPDAIKTVVKQAEQMASQE S |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 49 |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 49 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 49 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 43 |
