Gene Information

Name : Lreu_0751 (Lreu_0751)
Accession : YP_001271352.1
Strain : Lactobacillus reuteri DSM 20016
Genome accession: NC_009513
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 824442 - 825863 bp
Length : 1422 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta

DNA sequence : 
ATGAAGAAAACCAAGATTGTAAGTACACTTGGTCCTGCAAGTACTGATGTTGATACGATCGTTAAGTTGATCAATGCGGG
AGCTAACATTTTCCGTTTCAACTTCTCACACGGTGACCACCCAGAACACTTGGGTCGGATCGAAAACGTACACAAGGCTG
AAGAAATTACTGGCAAGCACGTTGGTCTTATGCTTGATACTAAGGGTGCCGAAATTCGGACTACTGTTCAAAAAGAAGGT
AAGATCAACTTTGAAATTGGCGACAAGGTTCGCATTTCAATGGATCCTTCAATTGAAGGTACTCATGACAAGATTGCTGT
TACCTACCCAGGCTTATACGATGATACTCATGTTGGTGGCCATGTTCTTTTTGATGATGGTTTAATTGACATGGTTATTG
ATGAAAAAGACGATGCAAACAAGGAACTTGTATGTCACGTCTTAAACCATGGTGTTCTTGGTTCTCGGAAGGGTGTTAAC
GCCCCTGGTGTATCAATCAACTTACCAGGTATTACTGAAAAGGACAGTAGCGATATTCGGTTTGGTTTGGAAAACAAGAT
CAACTACATTGCTGCATCTTTCGTTCGTAAGGCTCAAGATGTTCTTGACATTCGCGAATTACTTAAGGAAAAGAACATGG
AAGATGTTCAAATTTTCCCTAAGATTGAATCTCAAGAAGGTATCGACAACTTTGAAGAAATCATTGCTGTTTCTGACGGT
TTAATGGTACCTCGTGGTGACATGGGTGTTGAAATTCCTGCCCAAAATGTGCCAATTGTTCAAAAGCACATGATCAAGCG
TTGTAACGAATTAGGTAAGCCAGTTATTACTGCTACCCAAATGCTTGACTCAATGCAAGAAAACCCACGTCCAACCCGTG
CCGAAGTATCAGACGTTGCTAACGCCGTATTTGACGGTACTGATGCTACTATGCTTTCTGGTGAAAGTGCTAACGGTGAC
TACCCAGTTGAATCTGTTGCAATGATGAACGACATTGACATCAAGGCTGAAAACCACCTTTGGGAATTCGGTACTGAAAA
GTTCGATTGGGACAAGTCTGACGTAACTGAAACTATCGGTTCTGCTGTTGCTAACGCAGCTAAAGACTTAGACATTCACA
CAATTGTTGCTTACACTGCTTCAGGCTACACTGCTAAGATGATTTCTAAGTACCGTCCTAATGCTGATATCGTTGCATTA
ACTCCAAACGAACGTGTAGAACGTGGACTTATGATCAACTGGGGTGTTCAACCATACGTTGTTGATGAAATGAAGAACAC
TGATACAATGTTCGACTTAGCTGCTAAGAAGGCTGTTGAACTTGGCTTTGCTAAGAAGGGCGACAAGATCATCATCGTTG
CTGGTGTTCCTTTGGGTGTACCAGGTGCAACTAACATGATGCGTGTTAAGACTATCGACTAA

Protein sequence : 
MKKTKIVSTLGPASTDVDTIVKLINAGANIFRFNFSHGDHPEHLGRIENVHKAEEITGKHVGLMLDTKGAEIRTTVQKEG
KINFEIGDKVRISMDPSIEGTHDKIAVTYPGLYDDTHVGGHVLFDDGLIDMVIDEKDDANKELVCHVLNHGVLGSRKGVN
APGVSINLPGITEKDSSDIRFGLENKINYIAASFVRKAQDVLDIRELLKEKNMEDVQIFPKIESQEGIDNFEEIIAVSDG
LMVPRGDMGVEIPAQNVPIVQKHMIKRCNELGKPVITATQMLDSMQENPRPTRAEVSDVANAVFDGTDATMLSGESANGD
YPVESVAMMNDIDIKAENHLWEFGTEKFDWDKSDVTETIGSAVANAAKDLDIHTIVAYTASGYTAKMISKYRPNADIVAL
TPNERVERGLMINWGVQPYVVDEMKNTDTMFDLAAKKAVELGFAKKGDKIIIVAGVPLGVPGATNMMRVKTID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-93 46
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-93 46
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-93 46
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-93 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lreu_0751 YP_001271352.1 pyruvate kinase VFG0479 Protein 6e-94 46