Gene Information

Name : Lreu_0634 (Lreu_0634)
Accession : YP_001271236.1
Strain : Lactobacillus reuteri DSM 20016
Genome accession: NC_009513
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 702691 - 704118 bp
Length : 1428 bp
Strand : +
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGGCTGATGTTGAACAAAAGGATACAGTAATTGTTGGTGGAGGTCCTGGTGGTTATGTAGCCGCTATTCGAGCTTCAGA
ATTAGGTCAAAAGGTTACCTTAATTGATAAGGGAGAACCAGGTTTAGGTGGTGTTTGTTTAAACGTTGGATGTGTGCCAT
CTAAAGCATTAATTGCTGCTGGGCACCGTTACCAAGAAACTTTAGACTCATCTATTTATGGTATTTCTAAGACCGATGCA
AAGTTAGACTTTACTAAGACTCAAGAATGGAAAGACCATAAAGTTGTCGACCGTATGATTCGTGGAGTTAAGATGCTATT
GAAGAAGCATAAGGTTGAAATCATTGATGGAGAGGCAATTCTTGATAATGACCACCAACTTCGTGTAATTAAGCCTGGTC
CAAAGCAATTCATGGATAATGATAATGGTCGGACTATCACATGGAAGAATTTGATTCTTGCAACAGGAAGCCGTCCAGTA
GAAATTCCTCATTTTAAGTTTGAAGGCCGCGTTATTGATTCAACCGGTGGCTTAAACCTTAAGGAAGTACCAGAAGAATT
AGTTGTAATTGGTGGGGGCTACATTGGTACAGAATTAGCTGGTGCCTATGCCGATCTTGGTGCTCATGTAACAATTATTG
AAGGTACTGATTCAATTCTTGGTGGATTTGACCACGATATGGTTGATATTGTTGTCAAGAATCTTGAAAAGAAGGGCGTA
GACATTGTAACTAAGGCAATGGCTAAAGATTCTCAGCAAGATGAAAATAGTGTTACTGTCACTTATGAAGTTGATGGTAG
CGAAAAGAGCATTAAAGCAGACTACTGCATGGTATCTGTTGGTCGTAAACCAAATACTGATGATTTTGGCCTTGATATGA
CAAATGTTAAGTTAAACGACCGCCATCAAGTAATTGTTGATGAACAAGGCCGGACGAATGTACCTGGTATTTGGGCTATT
GGAGATATTGTTCCTGGTCCTGCACTTGCTCACAAGGCATTCTTTGAAGCTAAGACTGCTGCTGGTGCAATTGCTGGTAA
GAATACTGCTAACGATTGGGTTGGAGTGCCAATGGTTTGTTTTGCTGATCCAGAATTAGCTCAAGTTGGTATGACGGTTG
AAGAAGCTAAAGATAAAGGAATTGATGTATCTACTGCTCAGTTCCCATTTGCCGGTAATGCCCGTGCTGTTTCTCTTGAC
GCTGCCGAAGGATTTATTCGCTTAATCTACACTAAAGATAAGAAAAATGTTATTGGTGCTCAAGGTGTCGGCCCTGGTGT
TAGTGACCTTGCTGGTGAACTTTCATTGATTGTCAATTGTGGAATGAATGTTGAAGACGTTGCTTTAACAATCCATCCAC
ACCCAACTTTGAATGAACCTGTTCAAGAAGCTGCAGACATTGCGCTTGGCTTCCCAACACACATCTAA

Protein sequence :
MADVEQKDTVIVGGGPGGYVAAIRASELGQKVTLIDKGEPGLGGVCLNVGCVPSKALIAAGHRYQETLDSSIYGISKTDA
KLDFTKTQEWKDHKVVDRMIRGVKMLLKKHKVEIIDGEAILDNDHQLRVIKPGPKQFMDNDNGRTITWKNLILATGSRPV
EIPHFKFEGRVIDSTGGLNLKEVPEELVVIGGGYIGTELAGAYADLGAHVTIIEGTDSILGGFDHDMVDIVVKNLEKKGV
DIVTKAMAKDSQQDENSVTVTYEVDGSEKSIKADYCMVSVGRKPNTDDFGLDMTNVKLNDRHQVIVDEQGRTNVPGIWAI
GDIVPGPALAHKAFFEAKTAAGAIAGKNTANDWVGVPMVCFADPELAQVGMTVEEAKDKGIDVSTAQFPFAGNARAVSLD
AAEGFIRLIYTKDKKNVIGAQGVGPGVSDLAGELSLIVNCGMNVEDVALTIHPHPTLNEPVQEAADIALGFPTHI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 2e-85 45