Gene Information

Name : nrdF (Lreu_0322)
Accession : YP_001270929.1
Strain : Lactobacillus reuteri DSM 20016
Genome accession: NC_009513
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 368368 - 369387 bp
Length : 1020 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAACTGGAAGAATTTAAACCTGTAAATCAATATAAAGCAATCAATTGGAATGAAGTTTCCGACATGATCGATAAAGC
TACCTGGGAAAAGCTAACAGAACAGTTCTGGCTTGATACACGAATTCCTGTTGCCAATGATATGGATGATTGGCGTGAAT
TAGATGACGATCATCAATGGACTGTCGGACATGTTTTTGGTGGTTTAACCCTTCTTGATACTGTTCAATCAGAAGCAGGA
TTAACTGCCCTTAAAGAAGATGTTAAAACTCCTCATGAAACAGCAGTTCTTAATAACATCCAATTTATGGAATCAGTTCA
TGCTAAGAGTTACTCAACTATTTTCTCTACTCTTAATACCCCAGACCAAATCAAAGAAATCTTTGAATGGTCCGATACAG
AAGAATACTTGCAAAACAAGGCTGTCAAAATTGCAAATATGTACCTTGATCCAAGTCAAGACCCACTCAAAAAGAAAGTA
GCCAACGTTTTTCTTGAAACTTTCTTATTCTACTCTGGTTTCTACACTCCCCTTTATTATCTTGGTCACAACAAATTAAA
CAATGTGGCTGAAATCATTAAGCTAATTTTACGGGACGAATCAGTTCACGGGACATACATTGGATACAAGTTCCAAGTCG
GCTTACGTGATCGAACGGAAAAGCAACAACAAGATATGAAAGATTGGATGTATAATTTCCTTTATGAATTATATGATAAT
GAAGAAAAATACACTCATCTTCTTTATGATCAAGTTGGTTGGACAGATGATGTTTTAACCTTCATCCGTTACAACGCTAA
TAAGGCATTGATGAACCTTGGTCAAGATCCACTATTCCCTGATACCGCTTCTGATGTTAACCCAGTTGTTATGAACGGAA
TTTCTACTTCTACTTCTAACCACGATTTTTTTAGCCAAGTCGGCAATGGATATCGCATGGGTGCCGTTGAAGCAATGAAT
GATAGTGATTATGACGTTAAAGATCCAAACGCGGGAAAAGACATTAATGCCTGCGATTAA

Protein sequence :
MKLEEFKPVNQYKAINWNEVSDMIDKATWEKLTEQFWLDTRIPVANDMDDWRELDDDHQWTVGHVFGGLTLLDTVQSEAG
LTALKEDVKTPHETAVLNNIQFMESVHAKSYSTIFSTLNTPDQIKEIFEWSDTEEYLQNKAVKIANMYLDPSQDPLKKKV
ANVFLETFLFYSGFYTPLYYLGHNKLNNVAEIIKLILRDESVHGTYIGYKFQVGLRDRTEKQQQDMKDWMYNFLYELYDN
EEKYTHLLYDQVGWTDDVLTFIRYNANKALMNLGQDPLFPDTASDVNPVVMNGISTSTSNHDFFSQVGNGYRMGAVEAMN
DSDYDVKDPNAGKDINACD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 5e-71 48