Gene Information

Name : Lreu_0293 (Lreu_0293)
Accession : YP_001270900.1
Strain : Lactobacillus reuteri DSM 20016
Genome accession: NC_009513
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 342146 - 343288 bp
Length : 1143 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class-III

DNA sequence :
ATGAAATTCAACACACAATTAATTCATGGCGGTAATAGTGAGGATCCAACCACTGGTGCTGTCTCAACACCGATTTACCG
TTCATCAACATTCCATCAACACGTTCTTGGCGGTGAACCTAAATGGGAATATTCTCGAACAGGAAATCCAACACGTGCAT
CTCTTGAAAAATTAATCGCAGAGCTTGAACATGGGACAGCCGGCTTTGCATTTGCTTCCGGATCTGCTGCTATTCATGCT
ACTTTTTCTTTATTCTCTCAAGGCGATCATTTTGTAGTTGGTAGTGATGTATACGGGGGAACATTCCGGTTAATCAATAA
GGTATTAAAACGCTTTGGCCTTGAATTTACTGTTGTTGACATGCAAGACCTTGAAGCAGTCGAAAATGCAATTCAAGATA
ATACCGTTGCAGTTTATTTTGAAACACCAACTAATCCGCTCTTGCAAATCGCTGATATTAAAGCAATTGCTGATATCGCA
AAAAAGCATGGAATAAAGACAATTGTTGATAATACCTTTGCTACTCCTTATAACCAACAACCGTTAACTCTTGGGGCAGA
TATTGTTGTTCACTCCGCAACAAAATATTTAGGCGGCCATAGTGATGTTGTTGCCGGATTAGCAGTTACTAACGATGATG
AAATTGCTGAACAATTAGCATTCCTGCAAAACTCAATCGGTAGTACGCTTGGTCCTGATGATAGTTGGCTACTACAACGA
GGGATGAAAACTCTCGGTGCCCGGATGCGCGTTCACCAAGAAAATGCGAATGAAGTTATTAACTTCCTCCAAAATGATGA
CCATATTGGGAAAATTTATTATCCAGGCTTAAAAGATTTTCCTGGTCATGAGGTTGCGGCTAAGCAAATGCGTAACTTTG
GAGCAATGATCTCCTTTGAACTTAAGGATGGTTTAGATGCGAAGAAGTTTGTTGAAAGTCTACAATTGATTGATCTTGCC
GAAAGCTTAGGGGGAATTGAAAGTTTGATTGAAGTTCCAGCTGTCATGACCCATGGATCTATTCCCCGGGAAATAAGACT
AGAGAACGGAATTAAAGATGAGTTAATTCGTCTTTCAGTGGGAATCGAGGACCCTGAAGATATTATTGCTGACTTGCAAC
AAGCACTTAAAAAATTAGACTAA

Protein sequence :
MKFNTQLIHGGNSEDPTTGAVSTPIYRSSTFHQHVLGGEPKWEYSRTGNPTRASLEKLIAELEHGTAGFAFASGSAAIHA
TFSLFSQGDHFVVGSDVYGGTFRLINKVLKRFGLEFTVVDMQDLEAVENAIQDNTVAVYFETPTNPLLQIADIKAIADIA
KKHGIKTIVDNTFATPYNQQPLTLGADIVVHSATKYLGGHSDVVAGLAVTNDDEIAEQLAFLQNSIGSTLGPDDSWLLQR
GMKTLGARMRVHQENANEVINFLQNDDHIGKIYYPGLKDFPGHEVAAKQMRNFGAMISFELKDGLDAKKFVESLQLIDLA
ESLGGIESLIEVPAVMTHGSIPREIRLENGIKDELIRLSVGIEDPEDIIADLQQALKKLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-80 52
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-79 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-66 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lreu_0293 YP_001270900.1 cystathionine gamma-lyase BAC0207 Protein 1e-62 45