Gene Information

Name : Lreu_0019 (Lreu_0019)
Accession : YP_001270632.1
Strain : Lactobacillus reuteri DSM 20016
Genome accession: NC_009513
Putative virulence/resistance : Virulence
Product : two component transcriptional regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 21025 - 21732 bp
Length : 708 bp
Strand : +
Note : PFAM: response regulator receiver; transcriptional regulator domain protein

DNA sequence :
ATGGCAAAGAAAATTTTAGTTGTTGATGATGAAAAACCAATTTCTGATATCATCAAATTTAATCTTGAAAAAGAAGGATA
TGAAGTTGTCGTAGCCTATGATGGCGAAGCAGCTTTAGAACAAGTAGAAGCAGAAAATCCTGATTTAATTATTCTTGACC
TAATGCTGCCGAAGATCGATGGACTTGAAGTGGCCAAGCGGGTTCGAGCTAAGCATACCATGCCGATTATTATGGTAACC
GCTAAAGATTCGGAACTAGATAAAGTGCTAGGGCTTGAACTTGGGGCCGATGATTATGTTACTAAGCCATTCTCCAACCG
CGAACTAGTAGCACGAGTAAAGGCTAATTTACGGCGTCAAGCAACTCTGAAGGCACCAGCAGAGGAAGAAAATAATACCG
ATATTCAAATTGGCGACCTTACGATTCATCCTGAAGCTTACACCGTAACTAAGCGAGGCGAAAATATCAATTTAACGCAT
CGTGAATTTGAGCTTCTCCATTATCTAGCTCAACATATTGGACAAGTTATTAACCGTGAACACCTTCTTCAGACTGTATG
GGGTTATGACTATTTTGGGGATGTTCGGACAGTTGATGTGACCGTTCGTCGGCTTCGTGAAAAGATTGAAGATAACCCAA
GTCACCCCCAATGGTTAATTACCCGGCGTGGTGTTGGCTATTACCTAGCAAATCCTGATCAGAATTAG

Protein sequence :
MAKKILVVDDEKPISDIIKFNLEKEGYEVVVAYDGEAALEQVEAENPDLIILDLMLPKIDGLEVAKRVRAKHTMPIIMVT
AKDSELDKVLGLELGADDYVTKPFSNRELVARVKANLRRQATLKAPAEEENNTDIQIGDLTIHPEAYTVTKRGENINLTH
REFELLHYLAQHIGQVINREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPQWLITRRGVGYYLANPDQN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 6e-34 41
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 9e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_012469.1.7685629. Protein 3e-70 72
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_003923.1003749.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002758.1121668.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_009641.5332272.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_013450.8614421.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_007793.3914279.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_007622.3794472.p0 Protein 6e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002745.1124361.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_009782.5559369.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002951.3237708.p0 Protein 4e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002952.2859905.p0 Protein 7e-58 58
Lreu_0019 YP_001270632.1 two component transcriptional regulator HE999704.1.gene2815. Protein 9e-51 54
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_012469.1.7686381. Protein 7e-44 50
Lreu_0019 YP_001270632.1 two component transcriptional regulator AF155139.2.orf0.gene Protein 7e-42 48
Lreu_0019 YP_001270632.1 two component transcriptional regulator AE016830.1.gene1681. Protein 8e-45 47
Lreu_0019 YP_001270632.1 two component transcriptional regulator FJ349556.1.orf0.gene Protein 4e-43 47
Lreu_0019 YP_001270632.1 two component transcriptional regulator AE000516.2.gene3505. Protein 8e-35 44
Lreu_0019 YP_001270632.1 two component transcriptional regulator AM180355.1.gene1830. Protein 4e-40 44
Lreu_0019 YP_001270632.1 two component transcriptional regulator HE999704.1.gene1528. Protein 7e-31 44
Lreu_0019 YP_001270632.1 two component transcriptional regulator CP004022.1.gene3215. Protein 6e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator DQ212986.1.gene4.p01 Protein 4e-40 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_007622.3794948.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_003923.1003417.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_013450.8614146.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002951.3238224.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_007793.3914065.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002758.1121390.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_010079.5776364.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002952.2859858.p0 Protein 2e-37 43
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_002695.1.915041.p Protein 1e-34 42
Lreu_0019 YP_001270632.1 two component transcriptional regulator CP001918.1.gene5135. Protein 9e-30 42
Lreu_0019 YP_001270632.1 two component transcriptional regulator CP000034.1.gene3834. Protein 1e-34 42
Lreu_0019 YP_001270632.1 two component transcriptional regulator CP001138.1.gene4273. Protein 2e-34 42
Lreu_0019 YP_001270632.1 two component transcriptional regulator AF130997.1.orf0.gene Protein 4e-38 42
Lreu_0019 YP_001270632.1 two component transcriptional regulator AF162694.1.orf4.gene Protein 1e-37 42
Lreu_0019 YP_001270632.1 two component transcriptional regulator AE015929.1.gene1106. Protein 1e-31 42
Lreu_0019 YP_001270632.1 two component transcriptional regulator BAC0533 Protein 3e-34 41
Lreu_0019 YP_001270632.1 two component transcriptional regulator CP000647.1.gene4257. Protein 3e-34 41
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_014475.1.orf0.gen Protein 3e-39 41
Lreu_0019 YP_001270632.1 two component transcriptional regulator NC_005054.2598277.p0 Protein 3e-39 41
Lreu_0019 YP_001270632.1 two component transcriptional regulator EU250284.1.orf4.gene Protein 2e-38 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Lreu_0019 YP_001270632.1 two component transcriptional regulator VFG1563 Protein 3e-34 41
Lreu_0019 YP_001270632.1 two component transcriptional regulator VFG1702 Protein 4e-34 41
Lreu_0019 YP_001270632.1 two component transcriptional regulator VFG1386 Protein 4e-31 41
Lreu_0019 YP_001270632.1 two component transcriptional regulator VFG1389 Protein 2e-29 41