Gene Information

Name : hemC (Lreu_1702)
Accession : YP_001272278.1
Strain : Lactobacillus reuteri DSM 20016
Genome accession: NC_009513
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1763757 - 1764674 bp
Length : 918 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGACAAATAAAGTAATTGTTGGCAGTCGGAAAAGTAAACTAGCAATGGCGCAAACAGAATTGGTAATCGCTAGTTTGGA
AAAGATTTTCCCCGACATAAAATTTGAAATAAAAAACGTTATTACTGAAGGGGATCGAAACCGACATGTCAGCCTTGCTA
AAATCGGTGGGAAAGGCGTTTTCGTTAAAGAGATTGAAGACGAACTAAAAGATGGCACGATTGATTTTGCTGTTCATAGT
CTAAAAGATGTGATGCCGATTCTTCCAGAAGAATTAGTTTTAGGAGCATTTCCTAAACGAGTATCTCCATATGATTGTTT
AGTCAGCCGGAAAAATCTTTCATCGTTGAATGACCTTCCTAAAGGTGCACGAATCGGGACAAATAGTTTACGTCGCCAGG
GACAACTATTAAGTATTCGACCAGACTTAAAAATTATACCTATTAGGGGTAATATAGATACTAGGTTAAGAAAAATAGAC
ACAGAAGCGCTTGACGGTATTATTTTAGCTGAGGCTGGATTAACAAGATTAAATATTGACTTAAGTAGTTATCATGTTTT
GGATTTGCAAAATTATATTATGCCGGCAGTTGGTCAAGGCTGCTTAGCGATTGAATGCCGAAAAAATGACACTAGAATTC
GCAAAATGCTTGATCAAATTAATGATGAAGAATCAGCTTATTGTGTGCAAGTTGAGCGTGAATTTATGCGTGAATTGGGT
GGAAGTTGTAATTTCCCGATTGGGGGCCATGCCTACGCGAAAAATGGTCAAATTCTATTTGATGGGTTGATCGCTTCCCC
TAATGGTGAACATGTTATAAAAGAAACAAAAATACCTGCCAATAATTCTGGAGTCGGTAAAAAAGTTGCTGATCAGTTAT
TGGCTAAGGATAAATTTGGAATTATTGAAGGAGAATAG

Protein sequence : 
MTNKVIVGSRKSKLAMAQTELVIASLEKIFPDIKFEIKNVITEGDRNRHVSLAKIGGKGVFVKEIEDELKDGTIDFAVHS
LKDVMPILPEELVLGAFPKRVSPYDCLVSRKNLSSLNDLPKGARIGTNSLRRQGQLLSIRPDLKIIPIRGNIDTRLRKID
TEALDGIILAEAGLTRLNIDLSSYHVLDLQNYIMPAVGQGCLAIECRKNDTRIRKMLDQINDEESAYCVQVEREFMRELG
GSCNFPIGGHAYAKNGQILFDGLIASPNGEHVIKETKIPANNSGVGKKVADQLLAKDKFGIIEGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-47 42
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-47 42