Gene Information

Name : leuS (Lreu_1295)
Accession : YP_001271889.1
Strain : Lactobacillus reuteri DSM 20016
Genome accession: NC_009513
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1341066 - 1343486 bp
Length : 2421 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCTTACGATCATAAGACGATTGAAAAAAAGTGGCAAAAGTTTTGGAAGAAGAATGAGACTTTCAAGGCCGACCTTAA
TAAGGACCAAAAGAAATACTATGCACTAGACATGTTCCCATATCCATCTGGTCAAGGACTCCACGTTGGTCACCCAGAAG
GTTATACCGCTACGGATGTAATGTCACGGATGAAACGGATGCAAGGATTTAATGTATTACATCCAATGGGGTGGGATGCA
TTCGGTTTACCAGCCGAACAATATGCATTAAAGACCGGCCACAACCCTAAGGACTTTACGAACAAAAATATTGACCATTT
CCGTGACCAAATCCAATCACTTGGGTTCTCATATGACTGGGACCGCGAAGTAAATACGACTGATCCTAAGTTCTACAAGT
GGACTCAATGGATTTTTGAACAGCTCTACAAGAAGGGGCTTGCTTACGAAAGTGAAATTATGGTTAACTGGGCCCCTGAT
TTTATGGGTGGAACAGTTGTTGCCAACGAAGAGGTTGAAGACGGCAAGACTAAACGTGGTGGTTACCCCGTCTACCGTAA
GCCAATGCGTCAATGGGTTTTAAAGATTACTGCTTATGCGGACCGTTTGATTGATGACCTTGACCTTGTTGACTGGCCAG
AAAGCGTTAAGGAAATGCAACGTAACTGGATCGGTCGTTCAGAAGGTGCTTCAGTATTTTTCCCAGTTGTGGGGGATGAA
GATACTAAGATTGAAGTATTTACGACGCGGGCAGATACGCTCTTTGGTGCTTCTTATGTTGTTCTTGCTCCCGAACAAGA
ATTAGTAGATCAATTGACGACGCCAGAACACAAGGCGGAAGTTGAAAAGTACAAGGAAGAAGCATCACGGCGGTCTGACC
TTGAACGGACTGATTTAAATAAGGATAAGACCGGGGTATTTACTGGTTCTTACGTCATTAATCCAGTTAACGGTGAAAAA
CTGCCAATTTGGATCAGTGATTACGTGCTTGCCTCTTACGGAACCGGAGCAGTAATGGCTGTTCCTTCCGGTGATCAACG
GGATTATGACTTTGCTACTAAGTTTAACTTGCCAATCAAGCCTATTATTGAAGGTGCAGATATTTCAGAAGGTGCTTTTG
ATGGCGATGGTAAACACATTAATTCTGGCTTCCTTGATGGTTTAAACATTGCTGATGCAAAGCAAAAGATGATCGATTGG
CTTGAAGAACACGATGCTGGGCACAAGAAGGTTAACTACCGTCTTCGTGACTGGATCTTCAGTCGGCAACGTTACTGGGG
TGAACCAATTCCAGTTATCCACTGGGATGATGGGACAACCTCATTAGTTCCAGAAGATGAACTTCCACTTGAATTGCCAA
AGACTGATAACATTGAACCATCAGGAACTGGTGAAAGTCCATTAGCAAATGTTGAAGATTGGGTTAACGTTTATGACGAA
AATGGTCGTCATGGTCTTCGTGAGACTAACACCATGCCACAATGGGCTGGTTCATCATGGTACTGGCTTCGGTACACTGA
TCCTCATAATGACGAGGAATTTGCCTCAAAAGAAGCCCTGGATTACTGGTCACCAGTTGATCTCTATGTTGGTGGAGCTG
AACACGCTGTTCTTCACTTGCTCTATGCTCGATTCTGGCATAAGGTTCTTTATGACCTCGGTCTCGTACCAACTAAAGAA
CCATTCATGAAGCTTGTTAACCAGGGGATGATTCTTGGTTCAAACCATGAAAAGATGTCGAAGTCCAAAGGTAATGTTGT
TAACCCTGATGACATTGTTGACCAATATGGGGCTGATACTTTACGTCTTTACGAAATGTTCATGGGACCACTTGAAGAAT
CGGTACCTTGGGATGAAAAAGGACTTCATGGTGCTAATAAGTGGGTTCAACGTGTATGGCGGTTGTTGATGGATGATAAT
AACCACCTCCGTGACCGGGTATCCACTTTCAATGATGGTAAGCTTACCAAGGTTTACAATCAAACTGTTAAGAAGGTTAC
CGAAGACTACGAACGGATGCACTTCAATACGGCTATTTCTCAATTGATGGTCTTTGTAAACGAAGCCTACAAGGTTGATG
ATTTACCAGTTGAATACATGAAAGGCTTTGTAAAGATGATTGCACCAATCATGCCGCACATGGCTGAAGAACTCTGGAGT
CAATTTGGTGAGAGTGATACAATCACTTACCAACCATGGCCAACTTACGATCCAAAAGCTTTAGTTGAAGATGAAGTTGA
AATGATCGTTCAGGTTAACGGTAAGGTACGGGCTAAGATTAAGATGGCCAAGGATACTGACCGCGATGAAGCACAACAAC
TTGCTTTAGCAAACGAACATGTTAAGAAGTTTACTGATGGCAAGGATATTAAAAAAGTCATTGTTGTCCCTAACAAGATC
GTTAACATCGTTGCAAAATAG

Protein sequence :
MAYDHKTIEKKWQKFWKKNETFKADLNKDQKKYYALDMFPYPSGQGLHVGHPEGYTATDVMSRMKRMQGFNVLHPMGWDA
FGLPAEQYALKTGHNPKDFTNKNIDHFRDQIQSLGFSYDWDREVNTTDPKFYKWTQWIFEQLYKKGLAYESEIMVNWAPD
FMGGTVVANEEVEDGKTKRGGYPVYRKPMRQWVLKITAYADRLIDDLDLVDWPESVKEMQRNWIGRSEGASVFFPVVGDE
DTKIEVFTTRADTLFGASYVVLAPEQELVDQLTTPEHKAEVEKYKEEASRRSDLERTDLNKDKTGVFTGSYVINPVNGEK
LPIWISDYVLASYGTGAVMAVPSGDQRDYDFATKFNLPIKPIIEGADISEGAFDGDGKHINSGFLDGLNIADAKQKMIDW
LEEHDAGHKKVNYRLRDWIFSRQRYWGEPIPVIHWDDGTTSLVPEDELPLELPKTDNIEPSGTGESPLANVEDWVNVYDE
NGRHGLRETNTMPQWAGSSWYWLRYTDPHNDEEFASKEALDYWSPVDLYVGGAEHAVLHLLYARFWHKVLYDLGLVPTKE
PFMKLVNQGMILGSNHEKMSKSKGNVVNPDDIVDQYGADTLRLYEMFMGPLEESVPWDEKGLHGANKWVQRVWRLLMDDN
NHLRDRVSTFNDGKLTKVYNQTVKKVTEDYERMHFNTAISQLMVFVNEAYKVDDLPVEYMKGFVKMIAPIMPHMAEELWS
QFGESDTITYQPWPTYDPKALVEDEVEMIVQVNGKVRAKIKMAKDTDRDEAQQLALANEHVKKFTDGKDIKKVIVVPNKI
VNIVAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 62