Gene Information

Name : guaA (Pput_1072)
Accession : YP_001266417.1
Strain : Pseudomonas putida F1
Genome accession: NC_009512
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1205372 - 1206949 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGCCCTCGACATTCACGCTCACCGCATCCTGATCCTCGATTTCGGTTCCCAGTACACCCAGCTGATCGCCCGCCGCGT
GCGCGAAATCGGCGTGTACTGCGAACTGCACCCGTTCGACATGGACGATGAAGCGATCCGCGAATTCAACCCGCGCGGCA
TCATCCTTGCCGGCGGCCCCGAGTCGGTCCACGAAGCCAACAGCCCGCGCGCTCCGCAAGCCGTGTTTGACCTGAATGTG
CCTGTGCTGGGTATTTGCTACGGCATGCAGACCATGGCCGAGCAGATGGGCGGCAAGGTAGAAGGTTCCGACCTGCGTGA
GTTCGGTTATGCCCGCGTGGACGTTGTCGGCAAGAGCCGCCTGCTCGACGGCATCGAAGACCACGTTGACGACGACGGCG
TGCTGGGCCTGGACGTGTGGATGAGCCACGGTGACAAGGTCACCCAGATGCCTGGCAACTTCAACATTCTGGCCAGCACC
CCAAGCTGCCCGATCGCTGGCATGTACGACGACGTCCGCGGCTACTACGGCGTGCAGTTCCACCCTGAAGTGACCCACAC
CAAGCAAGGGGGTCGCATCCTGTCCCGCTTCGTGCAGGACATCTGCGGCTGTGAAGCCCTGTGGACGGCGTCCAACATCG
TCGAAGACGCCATCGCCCAGGTGCGTGCGCAAGTCGGTTCGGCCAACGTCCTGCTGGGCCTGTCCGGCGGCGTTGACAGC
TCGGTGGTTGCCGCGCTGCTGCACCGCGCCATCGGCGACCAGCTGACCTGCGTATTCGTCGACAACGGCCTGCTGCGCCT
GCACGAAGGTGACCAGGTGATGGCCATGTTCAAAGAGAACATGGGCGTCAAGGTGATCCGCGCCGACGCTGAAAAGCAGT
TCCTGGACAACCTGGCCGGCGAAGCCGACCCTGAGAAGAAGCGCAAGATCATCGGCCGCACCTTCATCGACGTGTTCGAT
GCCGAAGCCAGCAAGCTGGAGAACATCCAGTTCCTCGCCCAGGGCACCATCTACCCGGACGTGATCGAGTCGGCTGGCGC
CAAGAGCGGCAAGGCTCACGTGATCAAGTCGCACCACAACGTTGGTGGCCTGCCGGAGGAGATGAACCTCAAGCTGGTCG
AGCCGCTGCGTGAACTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAGCTGGGCCTGCCATACGACATGGTCTACCGC
CACCCGTTCCCGGGCCCGGGCCTGGGCGTGCGTATCCTCGGTGAAGTGAAGAAGGAATACGCCGACATCCTGCGTCGCGC
CGACCACATCTTCATCGAAGAGCTGCGCAAGGCCGACTGGTACCACAAGACCAGCCAGGCATTCGTGGTGTTCCAGCCGG
TCAAGTCGGTCGGCGTCGTCGGCGACGGCCGTCGCTACGCCTGGGTTGTGGCCCTGCGTGCCGTCGAGACCGTGGACTTC
ATGACCGCGCGTTGGGCACACCTGCCGTACGAGCTGCTGGAAACTGTCAGCGGTCGTATCATCAATGAAATCGACGGTAT
CTCGCGCGTTACCTACGATGTGTCGAGCAAGCCGCCGGCGACCATCGAGTGGGAATAA

Protein sequence :
MALDIHAHRILILDFGSQYTQLIARRVREIGVYCELHPFDMDDEAIREFNPRGIILAGGPESVHEANSPRAPQAVFDLNV
PVLGICYGMQTMAEQMGGKVEGSDLREFGYARVDVVGKSRLLDGIEDHVDDDGVLGLDVWMSHGDKVTQMPGNFNILAST
PSCPIAGMYDDVRGYYGVQFHPEVTHTKQGGRILSRFVQDICGCEALWTASNIVEDAIAQVRAQVGSANVLLGLSGGVDS
SVVAALLHRAIGDQLTCVFVDNGLLRLHEGDQVMAMFKENMGVKVIRADAEKQFLDNLAGEADPEKKRKIIGRTFIDVFD
AEASKLENIQFLAQGTIYPDVIESAGAKSGKAHVIKSHHNVGGLPEEMNLKLVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADILRRADHIFIEELRKADWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETVDF
MTARWAHLPYELLETVSGRIINEIDGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-127 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-127 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-127 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-111 48