Gene Information

Name : Swit_0637 (Swit_0637)
Accession : YP_001261143.1
Strain : Sphingomonas wittichii RW1
Genome accession: NC_009511
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 689952 - 691229 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCACGACATCCGCCTGATCCGCGAAGATCCCGCCGCCTTCGATGCCGCCATCGCCCGCCGGGGAGCCGAGTCGGCATC
GTCGCGGCTGCTCGCGCTCGACGAGCGCCGCCGCGCGATCGCGACCGAATTGCAGGCCGCGCAGACCCGCCGCAACGAGG
CGTCGAAGGCGATCGGCCAGGCCAAGGCGCAGAAGGACGAAGCGACCGCATCCGCGCTGATGGCCGAGGTCGCCGCGCTC
AAGGAGCGCATGCCCGCGCTGGAAGCCGAGGGCGCCGAGGTCGAGGCCGCGCTCGACGCCGCGCTCGCCGCGATCCCCAA
CCTGCCCGCCGCCGACGTTCCCGATGGCGCCGACGAGCAGGACAATGCCGAGCAGCACCGCTGGGGCACCCCGCCCGCCT
TCGCCTTCGAGGCGCGCGAGCATGCCGATTTCGCCGGTCCGCTGGGCCTCGACTTCGAGGCGGCCGCCGCGATCTCCGGC
GCGCGCTTCGCGGTGCTCAAGGGCGGCATCGCCCGGCTGCAGCGCGCGCTCGGCGCGTTCATGCTCGACCGGCAGACCGC
CGCCGGCTTCACCGAGGTGATCCCGCCGCTGCTGGTCCGCGACGAAGCGGTGTTCGGCACCGGCCAGCTCCCGAAGTTCG
CCGAGGACCTGTTTCGCACCACCGACGGCCGCTGGCTGATCCCGACCGCCGAGGTCAGCCTGACCAACCTGGTCCGCGAG
CAGATAGTGGCCGAGGCCGAACTGCCGATGAAGATGACCGCGCTCACCCCCTGCTTCCGTTCCGAGGCAGGTGCTGCGGG
CCGCGACACGCGCGGGCTGATCCGCCAGCACCAGTTCGAGAAGGTCGAGCTGGTCGCGATCACCACGCCCGAACAGTCCG
ACGCGGTCCACGAGGCGATGACCAAGGCGGCCGAGGCGATCCTGGAGGCGCTCGGCCTGCCCTATCGCCGCGTCCTGCTC
TGCACCGGCGACATGGGCTTCACCGCGCGCAAGACCTTCGACCTGGAGGTCTGGCTGCCGGGCCAGGGCTGCTATCGCGA
GATCAGCAGCGTCTCCAACTGCGGCGACTTCCAGGCGCGCCGGATGAACGCGCGCTATCGCCCGGCCGGCGAGAGCAAGG
GCACCCGCTTCGTCCACACCCTCAACGGATCGGGCCTCGCGGTCGGCCGCACCCTCGTCGCGGTGCTGGAGAATTACCAG
CAGGCCGACGGATCGGTGACGATCCCCGAGGCGCTCGTCCCCTATATGGGCGGGATCGCCGAGCTGCGCCCGGCATGA

Protein sequence :
MHDIRLIREDPAAFDAAIARRGAESASSRLLALDERRRAIATELQAAQTRRNEASKAIGQAKAQKDEATASALMAEVAAL
KERMPALEAEGAEVEAALDAALAAIPNLPAADVPDGADEQDNAEQHRWGTPPAFAFEAREHADFAGPLGLDFEAAAAISG
ARFAVLKGGIARLQRALGAFMLDRQTAAGFTEVIPPLLVRDEAVFGTGQLPKFAEDLFRTTDGRWLIPTAEVSLTNLVRE
QIVAEAELPMKMTALTPCFRSEAGAAGRDTRGLIRQHQFEKVELVAITTPEQSDAVHEAMTKAAEAILEALGLPYRRVLL
CTGDMGFTARKTFDLEVWLPGQGCYREISSVSNCGDFQARRMNARYRPAGESKGTRFVHTLNGSGLAVGRTLVAVLENYQ
QADGSVTIPEALVPYMGGIAELRPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-87 54