Gene Information

Name : Swit_4305 (Swit_4305)
Accession : YP_001264783.1
Strain : Sphingomonas wittichii RW1
Genome accession: NC_009511
Putative virulence/resistance : Virulence
Product : 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4748948 - 4750450 bp
Length : 1503 bp
Strand : +
Note : TIGRFAM: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase

DNA sequence :
ATGACCCAGGATCGCCGCAGCGGCGCCATCGACCGCATCACCGCCATCGACGACGGCTGCATCGGCCACTTCATCGCGGG
GCAGGCAGTGCCCGGCGCCGGCACCACCTTCGACGTGACGGAGCCCGCGACGGGCCAGTCGCTCGGCACCGCGCGCGACG
CGACCGCCGGGGAGCTCGACGCCGCCGTCAAGGCCGCCAAGGACGCTTTCCCCGCCTGGGCGGCGGTGCCGGGCGACAAG
CGCCGCGCCGTCCTCCACCGCATCGCCGACCTGATCGTCGAGCGGGCCGAGGAGATCGCCGCGGTCGAGTGCGTCGACGC
CGGCCAGTGCTGGCGCTTCATGTCGAAGGCGGCGATCCGCGGCGCGGAGAATTTCCGCTTCTTCGCCGATCGCGCGCCGG
GCGCCCGCGACGGCCAGGCGCTGCCGGCGGGCGGGCAGCTCAACGTCACCACCCGCACCCCGATCGGCCCGGTCGGCGTG
ATCACGCCGTGGAACACGCCGTTCATGCTGTCGACCTGGAAGATTGCCCCCGCGCTGGCGGCGGGCTGCACGGTCGTCCA
CAAGCCGGCCGAATGGTCGCCCTATTCGGCGCGCCTGCTGGTCGAGATCGCGCATGAGGCGGGGCTGCCCGCCGGCGTGT
TCAACGCGGTCAACGGCCTGGGCGAGACGACCGGCCGGCGGCTGACCGAGCATCCCGACATCAAGGCGGTGGCCTTCGTC
GGGGAATCGCGCACCGGATCGGCGATCATGAAGCAGGGCGCCGACACGCTGAAGCGCGTCCATTTCGAGCTGGGCGGCAA
GAACCCGGTCATCGTCTTCGACGACGCCGATCTCGATCGCGCGCTCGATGCCGTGGTGTTCATGATCTACTCGCTCAACG
GGCAGCGCTGCACCTCCTCGTCGCGGCTGCTGGTCCAGTCGTCGATCCGCGAAGCGTTCGAGGCGAAGCTCGCCGCGCGC
GTCGCCAACCTCAAGGTCGGCGATCCGCTCGACCCGGCGACCGAGGTCGGTCCGCTGATCCACCAGCGCCATCTCGACAA
GGTCGCCAGCTACATGGACATCGCCCGCGCCGACGGCGCGAAGATCGCGGTCGGCGGCGAGCGGATCGAGGGGGCCGGCT
ATTTCTTCCAGCCGACCCTGTTCACCGGCGCGGCCCAGTCGATGCGGATCGCGCAGGAGGAGATTTTCGGCCCGGTCCTG
ACCGTCATCCCGTTCGAGGACGAGGCCGACGCGATCGCCAAGGCGAACGACGTCGAATATGGCCTGGCCGGCTATGTCTG
GACCCGCGACATGGGCCGCGGCCTGCGCGTCTCGCAGGCGCTGGAGGCCGGCATGGTCTGGGTCAACAGCGAGAATGTCC
GCCACCTGCCGTCGCCGTTCGGCGGCGTGAAGGCGAGCGGCATCGGCCGCGACGGCGGCGACTGGAGCTTCGACTTCTAC
ATGGAGACGAAGAACATCGCGCTCGCCTATCAGGACCATGCGATCCAGAAGCTGGGCGCCTGA

Protein sequence :
MTQDRRSGAIDRITAIDDGCIGHFIAGQAVPGAGTTFDVTEPATGQSLGTARDATAGELDAAVKAAKDAFPAWAAVPGDK
RRAVLHRIADLIVERAEEIAAVECVDAGQCWRFMSKAAIRGAENFRFFADRAPGARDGQALPAGGQLNVTTRTPIGPVGV
ITPWNTPFMLSTWKIAPALAAGCTVVHKPAEWSPYSARLLVEIAHEAGLPAGVFNAVNGLGETTGRRLTEHPDIKAVAFV
GESRTGSAIMKQGADTLKRVHFELGGKNPVIVFDDADLDRALDAVVFMIYSLNGQRCTSSSRLLVQSSIREAFEAKLAAR
VANLKVGDPLDPATEVGPLIHQRHLDKVASYMDIARADGAKIAVGGERIEGAGYFFQPTLFTGAAQSMRIAQEEIFGPVL
TVIPFEDEADAIAKANDVEYGLAGYVWTRDMGRGLRVSQALEAGMVWVNSENVRHLPSPFGGVKASGIGRDGGDWSFDFY
METKNIALAYQDHAIQKLGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-76 46
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 3e-60 43
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-59 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-59 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-59 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-59 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Swit_4305 YP_001264783.1 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase VFG0082 Protein 5e-60 41