Gene Information

Name : hemC (Swit_1936)
Accession : YP_001262434.1
Strain : Sphingomonas wittichii RW1
Genome accession: NC_009511
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2169683 - 2170609 bp
Length : 927 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGACCGCTTCGCTCTCCCGTCCCCTCCGTCTCGGCACCCGCGGATCGCCGCTCGCGCTGACCCAGGCCCGCATGGTGAT
CGCCGCGCTGCGGGCCGCCCATGGATGGGACGAAACCGCGGTCGAGATCGTCGCGATCAAGACCAGCGGCGACCGCATCC
AGGATCGCGCGCTGGCCGAGGTCGGCGGCAAGGCGCTGTGGACCAAGGAGCTCGACATCGCCCTGGCGGACGGCACGATC
GACTTCGCGGTCCATTCGATGAAGGACGTCGAGACGATCCGCCCGGCCGCGATCGTCATCGCCGCGATGCTGCCCCGCGC
CGACGTGCGCGACCGGCTGATCGGCGCCGCCTCGCTGGCCGCGCTGCCGCAGGGCGCCCGGGTCGGCACCTCCTCGCCGC
GCCGGTCGGCGCAGGTCCGGCGCGCGCGGCCCGATGTCGGGATCGTGCTGTTCCGCGGCAATGTCGACACCCGCCTCGGC
AAGCTGGCGGCGGGCGAGGCGGAGGCGACGCTGCTCGCCGGCGCCGGCCTGATCCGGCTCGGCCGCGACGAGATCGGCCA
TCCGATCCCGATCGAGGAGATGCTGCCCGCCCCGGCGCAGGCCGCGGTCGGCATCGAGACGCTGGCCGAGCGAACGGACG
TGCGCGCGCTGCTCGGCGCGATCGACGACGCGCCGACCAACGCCTCCGTTTCGGCCGAACGCGCGCTGCTCGCCGCGCTC
GGCGCCGATTGCCGCTCGCCGGTGGCCGCGCTCGCCGTCCGGTCGGGCGCCGGGCTGCTGCTGCGCGCCGAGATCATGAC
CGAGGACGGCAGCGAGCATCGCTCGGGCGAGGCGATGCTGTTCGAGACCGGCGACGCCGCCGCGCTCGCCCACCGGCTGC
TCGACGGCGCCTCGCCCCGCCTCCGCGCGCTGTTCACCGGCGCATGA

Protein sequence :
MTASLSRPLRLGTRGSPLALTQARMVIAALRAAHGWDETAVEIVAIKTSGDRIQDRALAEVGGKALWTKELDIALADGTI
DFAVHSMKDVETIRPAAIVIAAMLPRADVRDRLIGAASLAALPQGARVGTSSPRRSAQVRRARPDVGIVLFRGNVDTRLG
KLAAGEAEATLLAGAGLIRLGRDEIGHPIPIEEMLPAPAQAAVGIETLAERTDVRALLGAIDDAPTNASVSAERALLAAL
GADCRSPVAALAVRSGAGLLLRAEIMTEDGSEHRSGEAMLFETGDAAALAHRLLDGASPRLRALFTGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-28 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-28 41