Gene Information

Name : Swit_1290 (Swit_1290)
Accession : YP_001261793.1
Strain : Sphingomonas wittichii RW1
Genome accession: NC_009511
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1442914 - 1444212 bp
Length : 1299 bp
Strand : +
Note : TIGRFAM: ATPase, FliI/YscN family; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; SMART: AAA ATPase

DNA sequence :
ATGCTGTCGGCGGTCGAGATCGACCATGCCGGCCCGCGCCGGATCGGCCGGCTCGCCTCCTATGACGGGCTGATGCTCGA
AGCGACCGGCTTCCCGATGCCGGTCGGCTCCAACGCCCGGGTGATCGACGCCGACGGCCATGCCGCGCTCGCCGAGGTGG
TCGGCTTCCGGGGCAACCGTACCTTGCTGATGGCCCTCGACGCCGACGCGCCGCACAGCGCGGGCGCGCGCGTCGAGCCC
GACCGGCGCGGCGGATCGGTCGACGTCGGCGAAACCCTGCTCGGCCGCGTGATGGACGCGCTCGGCAATCCGATCGACGG
GCTCGGCCCGATCGCCACCGCCGAGCGCTGGCCGCTGGCCGGCCGGCGCGGCAACCCGCTCGACCGCGCCCGCGTCACCG
AACCCTTCGACATGGGCGTCCGCGCGATCAACGCGCTGCTGACCGCCGGCGTCGGGCAGCGCATCGCGATCGCCGCCGGG
TCGGGCGTCGGCAAGTCGGTGCTGATGGGCCAGATGATCGCCGGCGCCGACGCCGACATCATCGTCGTCGGCCTGGTCGG
CGAGCGCAGCCGCGAGGTTTCGGACTTCCTGGCGACCAAGCTGGCCGGCCCGGTCCGCCAGAAGAGCGTCGTCGTCGCGG
TGCCCGCCGACCATCCGCCGGTGCTGCGCCTGCGCGCCGCGATGCGCGCGACCGCGATCGCCGAATATTTCCGCGCGCAG
GGCAAGCGCGTGCTGCTGCTGATCGACAGCCTGACCCGCGTCGCCCATGCGCAGCGCGAGATCGGCCTGTCGCTGGGCGA
GCCGCCGACGATGAAGGGCTATCCGCCCTCCGCGCTCGGCCTGATCCCGCGCCTGATCGAGCGCGCCGGGGTCGACGCCC
ATTCGGGCGGCTCGATCACCGCGCTCTACACGGTGCTCGCCGACGGCGACGACACCGACGACCCGATCGTCGACACCGCG
CGCGCGATCGTCGACGGCCACATCATCCTGTCGCGCAGCCTGGCCGAGCAAGGCGTCTTCCCCGCGATCGACGTCGGCAA
GTCGCTGAGCCGCGTGATGAGCGACATCGTCACGCCCGAGCACCAGCAGGCGGCGCAGATCCTCCGCCGGCTCTGGGCGG
TCTATGAGGAGAATCGCGACCTGATCCTGATGGGCGCCTATCGCGCCGGCAGCGATCCGATCGTCGACGTCGCGATCGCG
CGGCACGACCATATCCTCGAGTTCATCAGCCAGGGCCAGAAGGACCGCATCGACTATGCCCAGTCGGTCCAGGCGCTGCT
CGAGGCGTTCGGCGGATGA

Protein sequence :
MLSAVEIDHAGPRRIGRLASYDGLMLEATGFPMPVGSNARVIDADGHAALAEVVGFRGNRTLLMALDADAPHSAGARVEP
DRRGGSVDVGETLLGRVMDALGNPIDGLGPIATAERWPLAGRRGNPLDRARVTEPFDMGVRAINALLTAGVGQRIAIAAG
SGVGKSVLMGQMIAGADADIIVVGLVGERSREVSDFLATKLAGPVRQKSVVVAVPADHPPVLRLRAAMRATAIAEYFRAQ
GKRVLLLIDSLTRVAHAQREIGLSLGEPPTMKGYPPSALGLIPRLIERAGVDAHSGGSITALYTVLADGDDTDDPIVDTA
RAIVDGHIILSRSLAEQGVFPAIDVGKSLSRVMSDIVTPEHQQAAQILRRLWAVYEENRDLILMGAYRAGSDPIVDVAIA
RHDHILEFISQGQKDRIDYAQSVQALLEAFGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-70 47
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-70 47
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-69 47
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 4e-69 47
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-70 47
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-70 47
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-70 47
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-70 47
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-67 46
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-67 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 8e-66 46
escN AAC31513.1 L0034 Virulence LEE Protein 6e-66 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 8e-66 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-66 46
escN AAC38383.1 EscN Virulence LEE Protein 2e-66 46
escN CAI43874.1 EscN protein Virulence LEE Protein 3e-65 46
escN YP_003223475.1 translocator EscN Virulence LEE Protein 4e-65 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-65 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-65 45
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-65 45
escN AAK26715.1 EscN Virulence LEE Protein 9e-65 45
escN AAL57542.1 EscN Virulence LEE Protein 9e-65 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 7e-65 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-64 45
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-64 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-63 44
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-62 44
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-59 44
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-59 44
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-59 44
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-60 44
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-59 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 4e-59 43
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 4e-64 43
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-64 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 6e-64 43
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-64 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 6e-64 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-64 43
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 2e-67 43
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-64 43
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-58 42
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-58 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-52 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 5e-52 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-52 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 5e-52 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG1254 Protein 2e-83 52
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG2499 Protein 1e-75 50
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG2331 Protein 3e-77 49
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG0192 Protein 2e-68 46
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG0048 Protein 8e-68 46
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG0730 Protein 1e-66 46
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG0812 Protein 3e-66 46
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG0390 Protein 2e-68 45
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG0515 Protein 7e-60 44
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG2144 Protein 1e-60 42
Swit_1290 YP_001261793.1 FliI/YscN family ATPase VFG0555 Protein 2e-52 41