Gene Information

Name : Swit_1201 (Swit_1201)
Accession : YP_001261705.1
Strain : Sphingomonas wittichii RW1
Genome accession: NC_009511
Putative virulence/resistance : Virulence
Product : UDP-glucose/GDP-mannose dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 1360574 - 1361851 bp
Length : 1278 bp
Strand : -
Note : PFAM: UDP-glucose/GDP-mannose dehydrogenase; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; UDP-glucose/GDP-mannose dehydrogenase-like

DNA sequence : 
GTGAGCGTTGAACGAGGAACGAGCCGGATCGCGGTGATCGGTCTGGGATATGTCGGCCTGCCGCTGGCGGTGGCGCTGGC
GAAGCATTTTCCGACCGTCGGCATCGATATCGACCAGGGCCGCGTCGACGAGCTGAAGCGCGGCCATGACCGGACCAACG
AGCTGACCGCCGAGGCGCTCGCCGCCTCGACGCTGGCGCTGACCACGGCCATCGGCGAGGCGGCCGACGCCGACGTCGTC
ATCGTCACCGTGCCGACCCCGGTCGACCATGCCAACCGCCCCGATCTCGGCCCGGTCATGTCGGCGACCCGCAGCGTCGC
GTCGGTGCTGAAACCCGGCCGGGGGACGATCATCGTCTATGAGAGCACCGTCTATCCGGGCGTGACCGAGGACCTGTGCG
GGCCCGAGCTGGAGAAGCTGTCGGGCCTCAGGCGCGGCACCGACTTCTTCCTCGGCTACAGCCCCGAGCGGATCAACCCG
GGCGACCGTGAGCATACCGTCGATCGCATCACCAAGGTGGTGGCGGGCGAGAATCCGGAGGTGCTCGACAAGCTCTGCGC
GATCTATGGCGCGGTCACGACCGGCGGCACCTTCCGCGCCGCGTCGATCAAGGTGGCCGAGGCGGCGAAGGTGATCGAGA
ACGCCCAGCGCGACATCAACATCGCCTTCGTCAACGAGATCACCCAGATCTTCGGCAAGGTCGGCATCTCGATCTGGGAC
GTGCTGGCGGCGGCGGGGACAAAGTGGAACTTCCTGCGCTTCGTGCCGGGGCTGGTCGGCGGCCACTGCATCGGCGTCGA
CCCTTATTATCTCAGCTATCTCGCCCAGCAGCTCGGTCATGATCCGCGCGTCATCCTGGCGGGGCGCGGCACGAACGACG
GCATGGGCGCCTGGATCGCCGACCAGATCCACGAACGGATCGCCAGCGGATCGCGCGTCCTGATGCTCGGGCTGACCTTC
AAGGAGAATGTCCCCGACCTGCGCAATTCGCGGGTGATCGACGTCGTCCGCCGGCTCGAATGGCTGCGGCACGAGGTGGT
GATCCACGATCCGCTCGCCGACCCGGCCGAGGCGCGCCACGAATATGGCGTCGACCTCGCCGCCGACGCGCTCGACGGGC
GCTATGACGTGGTGATCGGCGCGGTCTCGCACGGCGACTATGCCGCGCTGCCGGCCGACCGGCTCGCCGCGCTGGTCAAG
CCGGACGGGCTGGTCGCCGATCTCAAGGGCATGTGGGGCGGGCTCGACCTGCCCGGCGTCCGCCGCTGGACGCTCTGA

Protein sequence : 
MSVERGTSRIAVIGLGYVGLPLAVALAKHFPTVGIDIDQGRVDELKRGHDRTNELTAEALAASTLALTTAIGEAADADVV
IVTVPTPVDHANRPDLGPVMSATRSVASVLKPGRGTIIVYESTVYPGVTEDLCGPELEKLSGLRRGTDFFLGYSPERINP
GDREHTVDRITKVVAGENPEVLDKLCAIYGAVTTGGTFRAASIKVAEAAKVIENAQRDINIAFVNEITQIFGKVGISIWD
VLAAAGTKWNFLRFVPGLVGGHCIGVDPYYLSYLAQQLGHDPRVILAGRGTNDGMGAWIADQIHERIASGSRVLMLGLTF
KENVPDLRNSRVIDVVRRLEWLRHEVVIHDPLADPAEARHEYGVDLAADALDGRYDVVIGAVSHGDYAALPADRLAALVK
PDGLVADLKGMWGGLDLPGVRRWTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 9e-83 51
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-77 47
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-77 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Swit_1201 YP_001261705.1 UDP-glucose/GDP-mannose dehydrogenase VFG0431 Protein 5e-78 47