Gene Information

Name : BOV_A0060 (BOV_A0060)
Accession : YP_001257141.1
Strain :
Genome accession: NC_009504
Putative virulence/resistance : Virulence
Product : type IV secretion system protein VirB4
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 62625 - 65120 bp
Length : 2496 bp
Strand : -
Note : this annotation is based on an automated transfer of annotation from Brucella suis 1330 GenBank records (AE014291 and AE014292); identified by match to protein family HMM PF03135; match to protein family HMM TIGR00929

DNA sequence :
ATGGGCGCTCAATCCAAATACGCGCAACAGCTCAATAATGAACGGTCACTTGCACCGTTCATTCCCTTCAGGAGCCAGGT
TGGCCCGACCACCGTGATAACGCGTGACGGTGATTTCGTGCGCACATGGCGCATCGCGGGCCTGGCTTTCGAGACGCAGG
ACAAGGAGAAACTGTTGATCCGCAAGGACCAGCTTAACACCTTGTTCCGTGCCATCGCCTCAAACAATGTGGCGCTGTGG
TCCCACAACGTACGGCGCAGAACCTGGGATCACTTGAAATCCTTCTTTTCCAATCCGTTCTGCGACGCTCTCGACAAGAA
GTATTACGGATCGTTTTCCGGCTACCGAATGATGTCAAACGAACTGTATCTGACGGTTATTTACCGGCCAGTGCCGGCGA
AGATCAGCAGGTTGTTCAACGTGGCCGTTCATCGTTCGCATGCGGAAATCTTACAGGAGCAGCAGCTTGCCATCCGCAAG
CTGGACGAAATCGGCAATCAAATTGAAACCAGCTTGCGTCGCTACGGTGGCGATGACGGGCGTGGCATCGAAGTGCTGAG
CACCTATGAGGACAAACACGGCGCACTGTGCTCACAGCAGCTTGAATTTTATAACTTCCTTCTCTCAGGCGAATGGCAGA
AGGTGCGCGTGCCATCCTGCCCACTAGATGAATATCTGGGCACCGGGTGGGTGTATGCTGGCACTGAAACCATCGAGATA
CGCACCGCGAACGCGACGCGCTATGCGCGTGGCATCGATTTCAAGGACTATGCGAGCCACACCGAGCCGGGCATTTTGAA
CGGCCTGATGTATAGCGATCACGAGTACGTCATCACACAATCCTTCAGCTTCATGACAAAGCGGGATGGCAAGGAGTTCC
TGACACGGCAAAAGCAGCGGCTCCAAAATACCGAAGACGGCAGCGCATCCCAGATCATGGAAATGGACATTGCCATCGAC
CAGCTCGGCCGGGGCGATTTCGTCATGGGTGAATATCATTATTCGCTGCTGGTATTTGCCGAAGACATGGAGACGGTGCG
CCACAACACATCACATGCGATGAACATCCTGCAAGACAATGGTTTTCTGGCGACGGTGATCGCCACGGCCACGGATGCGG
CGTTCTATGCACAACTGCCATGTAACTGGCGGTATCGGCCGCGCGTGGCGGGCCTGACCTCGCTCAACTTCGCCGGTCTG
TCATGTTTCCATAATTTCCGCGCAGGCAAGCGGGATGGCAACCCCTGGGGGCAGGCATTGACGCTGCTCAAAACCCCTTC
CGGACAGCCCGCCTACCTGAACTTCCACTATTCAAAAGGCGACGAAGACAACTTCGACAAGAAGCTTCTGGGCAATACCC
GCATCATCGGCCAGTCCGGCGCTGGTAAAACTGTCCTGATGAACTTCTGCCTCGCGCAAGCGCAGAAGTATTTGCACAAT
GCTCCGATGGGTATGTGCAACGTCTTTTTCGACAAGGATCAAGGCGCGAAAGGGACTATTCTTGCCATTGGCGGCAAATA
CCTTGCCATCAGGAACGGCGAACCCACCGGGTTCAACCCATTCCAGATGGAGCCAACAGCGGGGAACATCCTGTTCCTTG
AAAAACTCGTACAGGTACTGGTATCGCGTGATGGCCAGCACGTGACCACAACGGACGAAAGCCGGATCAGTCATGCCATA
CGTACGGTCATGCGCATGCGCCCGGAGCTGCGGCGTCTGTCGACGGTGCTGCAAAACGTTACCGAAGGCAGCGACCGCCA
AGATCGTGAAAACAGCGTGGCGAAGCGGCTCGCGAAGTGGTGTTTTGATGACGGCACCGGCAAGCGGGGCACATTCTGGT
GGGTGCTGGATTGCCCGCAAGACCAGATCGACTTCAACACGCATAGCAATTACGGTTTCGATGGCACCGACTTCCTCGAC
AACGCCGACGTGCGTACGCCGATTTCCATGTACCTGCTGCATCGTATGGAATTGGCTATCGACGGGCGTCGTTTCATCTA
CTGGATGGACGAGGCGTGGAAGTGGGTAGACGACGAAGCATTCAGCGAGTTCGCCAATAACAAGCAGCTTACCATCCGCA
AGCAAAACGGCCTGGGCGTGTTTGCCACGCAAATGCCCTCCAGCCTGCTCAACTCCAAAGTCGCGTCGGCCCTGGTGCAA
CAGGTGGCGACGGAAATCTATCTGCCGAATCCGAAAGCCGATTATCACGAGTACACGGACGGCTTCAAGGTGACGAACGA
GGAGTTCGACATCATCCGCAGTATGAGCGAGGAAAGCCGCATGTTCCTGGTCAAGCAGGGGCATCATTCGATGATTTGCC
GCCTGGAGCTTAATGGCTTTGATGACGAACTGGCGATCCTCTCAGGCAGCTTGGACAACAACGAGTTGCTGGACCAGGTC
ATTGCCGAAGTCGGGGACGACCCTTCGGTATGGCTTCCGGTGTTCCAGGAGCGCCGGAAAGCACGCATTGCGTCGTCCAA
ATCAACAGGAAGGTGA

Protein sequence :
MGAQSKYAQQLNNERSLAPFIPFRSQVGPTTVITRDGDFVRTWRIAGLAFETQDKEKLLIRKDQLNTLFRAIASNNVALW
SHNVRRRTWDHLKSFFSNPFCDALDKKYYGSFSGYRMMSNELYLTVIYRPVPAKISRLFNVAVHRSHAEILQEQQLAIRK
LDEIGNQIETSLRRYGGDDGRGIEVLSTYEDKHGALCSQQLEFYNFLLSGEWQKVRVPSCPLDEYLGTGWVYAGTETIEI
RTANATRYARGIDFKDYASHTEPGILNGLMYSDHEYVITQSFSFMTKRDGKEFLTRQKQRLQNTEDGSASQIMEMDIAID
QLGRGDFVMGEYHYSLLVFAEDMETVRHNTSHAMNILQDNGFLATVIATATDAAFYAQLPCNWRYRPRVAGLTSLNFAGL
SCFHNFRAGKRDGNPWGQALTLLKTPSGQPAYLNFHYSKGDEDNFDKKLLGNTRIIGQSGAGKTVLMNFCLAQAQKYLHN
APMGMCNVFFDKDQGAKGTILAIGGKYLAIRNGEPTGFNPFQMEPTAGNILFLEKLVQVLVSRDGQHVTTTDESRISHAI
RTVMRMRPELRRLSTVLQNVTEGSDRQDRENSVAKRLAKWCFDDGTGKRGTFWWVLDCPQDQIDFNTHSNYGFDGTDFLD
NADVRTPISMYLLHRMELAIDGRRFIYWMDEAWKWVDDEAFSEFANNKQLTIRKQNGLGVFATQMPSSLLNSKVASALVQ
QVATEIYLPNPKADYHEYTDGFKVTNEEFDIIRSMSEESRMFLVKQGHHSMICRLELNGFDDELAILSGSLDNNELLDQV
IAEVGDDPSVWLPVFQERRKARIASSKSTGR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
trwK YP_001610476.1 TrwK protein Virulence Not named Protein 1e-158 42
trwK CAD42844.1 TrwK protein Not tested trw-PAI Protein 1e-158 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BOV_A0060 YP_001257141.1 type IV secretion system protein VirB4 VFG2211 Protein 0.0 99
BOV_A0060 YP_001257141.1 type IV secretion system protein VirB4 VFG0018 Protein 0.0 52
BOV_A0060 YP_001257141.1 type IV secretion system protein VirB4 VFG2259 Protein 1e-159 42