Gene Information

Name : guaA (BOV_A0328)
Accession : YP_001257376.1
Strain :
Genome accession: NC_009504
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 340944 - 342506 bp
Length : 1563 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCACCACGGCATATCCTGACACAATCCTTATCATCGACTTTGGCAGCCAGGTCACGCAGCTTATTGCGCGGCGTGT
GCGCGAGGCCAATGTCTATTGCGAAATCGTTCCCTTCCAGTCTGCGGATGAGGCGTTCAAGCGGCTGCAGCCGAAGGGCG
TGATCCTTTCCGGCAGCCCGCATTCAACGACCGATATCGGTTCGCCGCGTGCGCCGCAGGCTATTTTTGATGCGGGTATT
CCGGTTCTCGGCATTTGTTATGGCGAGCAGACCATGTGCGCCCAGCTTGGCGGCAACGTGGAAAGCGGCCATGATCGCGA
GTTCGGCCGTGCTTTTCTCGATGTGCAGGAAGACAGTCCGCTCTTTGCCGGCATATGGGCCAAGGGCACCCGCCATCAGG
TCTGGATGAGCCATGGCGACCGTGTGACCTCGCTGCCGGATGGCTTCACCATCATCGGCACGTCGCCGAATGCGCCCTAC
GCGGTTATTGCGGATGAAAAGCGCAAATATTACGGCGTGCAGTTCCATCCGGAAGTTGTGCACACGCCGGACGGTGCAAA
GCTGTTGCAGAATTTCGTTCATCGCATTGTCGGGGTGAAGCCAGGCTGGACGATGGGGGCCTATCGCGAACAGGCTGTCG
AGGCGATCCGCAAACAGGTCGGCAGCGGCAAGGTTATCTGCGCGCTTTCAGGCGGCGTGGATTCTTCCGTGGCGGCACTT
CTGGCTCATGAAGCTGTCGGCGATCAACTGACATGCATTCTCGTTGATCACGGCCTGATGCGCAAAGACGAAGCGCAACA
GGTCGTGGAAATGTTCCGCGAGCATTACAATCTGCCGCTGATCCTGGTGGATGCTTCCGACCGCTTCATCGGCGCGCTTG
AGAGCGAAAGTGACCCGGAAAAGAAGCGCAAGACCATCGGTCGCCTGTTTATCGAAGTGTTCGAGGAAGAAGCAAGGAAA
CTTGGCGGCGCGGATTTCCTCGTGCAGGGTACGCTTTATCCTGACGTGATCGAAAGTGTTTCCTTTACCGGCGGCCCTTC
GGTCACGATCAAGTCGCACCATAATGTCGGCGGTTTGCCGGAGCGCATGAAGATGCAGCTTGTGGAGCCGCTGCGCGAGC
TTTTCAAGGATGAGGTTCGTCTGCTCGGCAAGGAACTCGGTCTGCCGGACAGCTTCATCGGGCGTCATCCGTTCCCCGGT
CCGGGTCTTGCGATCCGTTGTCCCGGCGGCGTCACGCGCGAGAAACTGGAAATCCTGCGCGAAGCGGACGCAATCTATCT
GGATGAAATCCGCAAGGCTGGCCTCTATGATGCGATCTGGCAGGCTTTCGCGGTTCTGCTTCCGGTGCAGACCGTGGGCG
TGATGGGGGATGGCCGCACTTACGAATTCGTTTGCGCCTTGCGCGCGGTGACTTCGGTGGACGGCATGACGGCGGATTTC
TACCACTACGACATGAATTTCCTCGGCAATGCGGCCACCCGCATCATCAACGAAGTCCGCGGCATCAACCGCGTTGTCTA
TGATGTGACCTCCAAGCCGCCCGGCACGATTGAGTGGGAATAA

Protein sequence :
MSTTAYPDTILIIDFGSQVTQLIARRVREANVYCEIVPFQSADEAFKRLQPKGVILSGSPHSTTDIGSPRAPQAIFDAGI
PVLGICYGEQTMCAQLGGNVESGHDREFGRAFLDVQEDSPLFAGIWAKGTRHQVWMSHGDRVTSLPDGFTIIGTSPNAPY
AVIADEKRKYYGVQFHPEVVHTPDGAKLLQNFVHRIVGVKPGWTMGAYREQAVEAIRKQVGSGKVICALSGGVDSSVAAL
LAHEAVGDQLTCILVDHGLMRKDEAQQVVEMFREHYNLPLILVDASDRFIGALESESDPEKKRKTIGRLFIEVFEEEARK
LGGADFLVQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRLLGKELGLPDSFIGRHPFPG
PGLAIRCPGGVTREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMNFLGNAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-135 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-135 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-134 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-113 49