Gene Information

Name : arsA (CBO0755)
Accession : YP_001253293.1
Strain : Clostridium botulinum ATCC 3502
Genome accession: NC_009495
Putative virulence/resistance : Resistance
Product : arsenical pump-driving ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 856225 - 857970 bp
Length : 1746 bp
Strand : +
Note : -

DNA sequence : 
ATGTTTAAAAAATTTAATGTGGAAGATATAAACTTAACAAAATATTTGTTCTTTACTGGCAAAGGTGGAGTTGGTAAGAC
TTCAACAGCTTGTGCTGTAGCAGTAACTTTAGCTGATAAAGGTAAAAAAATTATGCTTGTTAGTACAGATCCAGCTTCAA
ATCTTCAAGATGTTTTTAATACAAAATTAAATAATAAGGGAGTTACTATAAAAGAAGTTCCTAATTTGGTAGTTGCAAAC
TTTGAACCAGAAGAAGCAGCTGCTGAATATAGAGAAAGTGTAATAGCACCTTATCGTGGAAAATTACCAGAAGCAGTTTT
GAAAAATATGGAGGAACAGCTTTCAGGTTCATGTACTGTTGAGATTGCTGCATTTAATGAATTCTCAACCTTTATAACTG
ATGAAAAAGTAGAAAAAGAGTATGACCATATTATATTTGATACAGCACCAACAGGTCATACACTAAGGATGTTGCAGCTT
CCGTCAGCATGGAGCAATTTTATTAATGAAAGTACACATGGTGCTTCATGTTTAGGACAGCTTTCAGGACTTGAAAGTAA
AAAAGAAGTTTATAAAAATGCAGTAAATACTCTAGCGGATAAGGATAAAACTACACTTATACTTGTATCACGTCCAGAAG
TATCACCTTTAAAGGAAGCTGAAAGAGCTTCTAAAGAACTTCAAGATATAGGGGTAAACAATCAAGTTTTAGTTATTAAT
GGAGTACTTGAAGAGCATGAAGATTATCTTTCTAATGCTATTTATACTAAACAACAAAAAGCATTAGAAGACATTCCAGA
ATCACTAAAGATCGTTGAAACTTTTCAAATTCCATTAAGACCTTATAATGTAACAGGTTTAGAAAATCTAAGAGCTTTTT
TAAAGAATAATAATATTAAATATAATGATGAAAAATTAAATACTACTAATATACCTAAATTAAATAAGGTAATAGAAGAT
TTATATAATACTGATAAAAAAGTAATATTTACAATGGGTAAAGGTGGTGTAGGTAAAACTACAATAGCTGCTGCAATTGC
TGTAGGATTAGCTAAAAAAGGAAAGAAAGTACATTTAACAACTACTGATCCAGCAGATCATTTAAAATTTGTGTTAGATG
AGGATTATGGAATAACTCTAAGCCATATAGACGAAAAAAAGGAACTAGAAAAATACAAAGAAGAGGTATTAATTAAAGCA
CGAAAAACCATGAGTGAAGATGATATCGCTTATGTTGAAGAAGATTTAAGATCACCTTGTACTCAAGAAATTGCAGTATT
TAGAGCATTTGCAGAAATAGTTGAAAGGTCAGAAAATGAGGTTGTAGTTATTGATACAGCACCAACAGGACACACTTTAT
TACTTTTAGACTGTACTCAAAGTTATAATAAAGAAATTCAACGTTCACAAGGAGATATTCCAAAATCAGTTAAGAAGCTT
TTACCTAAGCTTAGAAATGAGGAGCATACAGAAGTAATTATCGTAACATTAGCTGAAACAACTCCAGTTTATGAGGCTAT
GAGACTTCAGGAAGATTTGAATAGAGCTGGCATTCACAGTAAATGGTGGGTTATCAATTCAAGTTTTTATGTAGCTGATA
CAACAAATTCTATCTTAAAGGTAAAAGCCAATAATGAGATACAGTGGATTAATAAAGTGAATGAAATATCTAAAGGCAAT
TTTGCAGTTATAGAGTGGATGCCTGAAGAGGTTAAGGGGGAGATGCTTAACCGCTTAATAAAATAA

Protein sequence : 
MFKKFNVEDINLTKYLFFTGKGGVGKTSTACAVAVTLADKGKKIMLVSTDPASNLQDVFNTKLNNKGVTIKEVPNLVVAN
FEPEEAAAEYRESVIAPYRGKLPEAVLKNMEEQLSGSCTVEIAAFNEFSTFITDEKVEKEYDHIIFDTAPTGHTLRMLQL
PSAWSNFINESTHGASCLGQLSGLESKKEVYKNAVNTLADKDKTTLILVSRPEVSPLKEAERASKELQDIGVNNQVLVIN
GVLEEHEDYLSNAIYTKQQKALEDIPESLKIVETFQIPLRPYNVTGLENLRAFLKNNNIKYNDEKLNTTNIPKLNKVIED
LYNTDKKVIFTMGKGGVGKTTIAAAIAVGLAKKGKKVHLTTTDPADHLKFVLDEDYGITLSHIDEKKELEKYKEEVLIKA
RKTMSEDDIAYVEEDLRSPCTQEIAVFRAFAEIVERSENEVVVIDTAPTGHTLLLLDCTQSYNKEIQRSQGDIPKSVKKL
LPKLRNEEHTEVIIVTLAETTPVYEAMRLQEDLNRAGIHSKWWVINSSFYVADTTNSILKVKANNEIQWINKVNEISKGN
FAVIEWMPEEVKGEMLNRLIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 4e-121 47
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 4e-118 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsA YP_001253293.1 arsenical pump-driving ATPase ArsA BAC0571 Protein 4e-117 46
arsA YP_001253293.1 arsenical pump-driving ATPase ArsA BAC0572 Protein 5e-117 46
arsA YP_001253293.1 arsenical pump-driving ATPase ArsA BAC0030 Protein 3e-116 46