Gene Information

Name : fliP (CBO2648)
Accession : YP_001255147.1
Strain : Clostridium botulinum ATCC 3502
Genome accession: NC_009495
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 2801256 - 2802032 bp
Length : 777 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence : 
ATGAAGAAAAGAAATAACAGAATGATGTTTATGGTTTTACTAGCTTTAGGTATAGTGTTTTTTTATTCCATGAAAGCCTA
TGCAGCACCACAAAATACCATGCCTATACCCAAAATAAATATTTCTGTAGATAATGCTAATAATCCCACGGAGTATGTAG
ATAATATAAAGCTGTTAATAATGTTAACTGTATTAACATTACTGCCATCTTTTATAGTAATGATGACAAGCTTTGTAAGA
ACAATTGTGGTATTTGGATTTTTAAGAAATGCTATGGGAACACAACAATCTCCACCTAATCAGGTAATGATTGGTCTAGC
ACTTTTTTTAACTTTATTTATAATGCAACCGGTATATAGCGAAATAAATACTAAGGCTATACAACCCTATATGAAAAATA
AAATTACTCAAGAACAGGCAGTAGAAATAGGGGCCAAGCCTCTTAGACAATTTATGCTAAAGCAAACAAGGCAAAAGGAT
TTAAAATTGTTTGTGGAGCTCGCAAAGCCTAATTTTAAAGTAACAAAGGATAATGCACCTTTATATATAGTTGTACCTGC
CTTTATAATAAGTGAGCTTAAAACAGCTTTTCAAATAGGATTTTTATTATTTATTCCATTTTTAATTATAGATTTAGTAG
TAGCTAGTGTACTTATGTCTATGGGTATGTTTATGTTACCACCGGTCATGATATCTCTGCCCTTTAAGCTTTTGTTGTTT
GTAATGGTAGACGGATGGTACCTTCTGGTGAAATCTTTAGTAATGAGTTTTGGTTAG

Protein sequence : 
MKKRNNRMMFMVLLALGIVFFYSMKAYAAPQNTMPIPKINISVDNANNPTEYVDNIKLLIMLTVLTLLPSFIVMMTSFVR
TIVVFGFLRNAMGTQQSPPNQVMIGLALFLTLFIMQPVYSEINTKAIQPYMKNKITQEQAVEIGAKPLRQFMLKQTRQKD
LKLFVELAKPNFKVTKDNAPLYIVVPAFIISELKTAFQIGFLLFIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLF
VMVDGWYLLVKSLVMSFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcR AAP34349.1 HrcR Virulence Hrp PAI Protein 5e-23 42
hrcR BAB07862.1 HrcR Virulence Hrp PAI Protein 3e-22 42
ssaR YP_216427.1 type III secretion system protein Virulence SPI-2 Protein 7e-22 42
ssaR NP_460384.1 type III secretion system protein Virulence SPI-2 Protein 7e-22 42
ssaR CAA68199.1 secretion system apparatus, SsaR Virulence SPI-2 Protein 5e-22 42
lscR AAO18040.1 LscR Virulence TTSS locus Protein 7e-25 42
YPO0270 YP_002345352.1 type III secretion system protein Virulence Not named Protein 9e-24 42
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 8e-22 42
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 8e-22 42
hrcR NP_640757.1 type III secretion system protein Virulence Hrp PAI Protein 1e-22 42
hrcR YP_362153.1 type III secretion system protein Virulence Hrp PAI Protein 1e-22 42
XC_3016 YP_244084.1 type III secretion system protein Virulence Hrp PAI Protein 4e-23 42
hrcR NP_636600.1 type III secretion system protein Virulence Hrp PAI Protein 4e-23 42
hrcR AAD21321.1 HrcR Virulence Hrp PAI Protein 7e-23 42
hrcR YP_198720.1 type III secretion system protein Virulence Hrp PAI Protein 4e-22 42
hrcR AAT96262.1 HrcR Virulence S-PAI Protein 4e-18 41
hrcR AAT96303.1 HrcR Virulence S-PAI Protein 4e-18 41
hrcR AAT96343.1 HrcR Virulence S-PAI Protein 4e-18 41
yscR NP_456109.1 putative type III secretion protein Virulence SPI-2 Protein 3e-21 41
yscR NP_805090.1 type III secretion system protein Virulence SPI-2 Protein 3e-21 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG2338 Protein 2e-40 60
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG2494 Protein 6e-41 53
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG2016 Protein 8e-41 52
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG1259 Protein 2e-47 52
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG0394 Protein 6e-26 44
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG0519 Protein 3e-22 42
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG0188 Protein 6e-27 42
fliP YP_001255147.1 flagellar biosynthesis protein FliP VFG0044 Protein 1e-23 41