Gene Information

Name : gbsA (LPC_0314)
Accession : YP_001249655.1
Strain : Legionella pneumophila Corby
Genome accession: NC_009494
Putative virulence/resistance : Virulence
Product : glycine betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 335661 - 337127 bp
Length : 1467 bp
Strand : +
Note : -

DNA sequence :
ATGGAAATTTACGAAATGTACATTGATGGAAAATTTACTTTAGCCAAAAGCGGAACTACTCGCGACATTTTTGATCCGGC
TAACGGGGAATTGATTGCAAGAGTGCCAGAAAGTGCCAAAGAAGATGCCATACTTGCTATCAAAGCAGCGAGAAAAGCCT
TCGATGAAGGAGAGTGGAGAAAATCACTGGCGCTTGATCGAGGCAAATTGTTATTCAAGCTTGCTGATTTGATTCGAGCC
AATGCTAAAATGTTGGCAGAGCTGGAAACTAGAAATTGCGGAAAGCCGTTACCCGAAGCGGAGTTTGATGTCACTGATGC
TGCCAATTGCTTTGAATTTTACGGTGGGCTTGCGACTAAAATTCATGGTGAAACGATGTCGGTTCCAGCGAATTCATTTA
GTTACGTAGTACGTGAACCCATAGGCGTGTGTGGGCAAATCATTCCATGGAATTTTCCACTGCTTATGGCGGCCTGGAAG
CTTGCACCCGCACTTGCCGCAGGCAATACCGTGGTATTAAAACCATCAGAATTGACCCCGATAACGGCACTTGAGTTATT
CAAGTTGATTGATCAATGCGGATTTCCCGCGGGCGTGGTTAACCTCATTACTGGGCCGGGTATGGGAGTTGGAGAGGAGT
TGGCAAGTAATTCTATGGTGGATAAGGTTGCTTTCACCGGAGGATCGGCAACAGGCAGAAAAATCATGCAGGCAGCTACT
GGCAATTTGAAAAAAACCTCGTTAGAGCTTGGCGGAAAAAATCCAAATATTGTCTTTGCAGACTGTGACCTTGAAATGGC
AATCGACGGCGCCCTTTTTGGTGCTTTTGCAAATCAAGGGGAGGTCTGTTCTGCGGGTTCCCGCTTGCTAGTGGAGCGCT
CTATTCACAAAAAAATAGTAGAGGGAATGTTGAAAAAAATTCCAAATATCAAGCTTGGCCATGGTTTGGACGCTGGGGTA
AAAATGGGGCCTTTGGTTTCAAGTGCACATCGAGAAAAAGTGGAAAGCTATGTCAAGCTTGGAATGGAAGAAGGGGCCAA
ATTACTTTGCGGCGGTAAACGCCCGACAGGCAGTGAATTTGCAAAGGGACATTTTTTCGAGCCAACCATTTTTGATGAAG
TGAAATCCACGATGCGTATTGCTCGTGAAGAAATTTTTGGTCCAGTACTTGTGGTCATCCCCTTTGATACAGAAGAAGAA
GCCATTCGCATTGCGAACGATACTGATTATGGTTTATCTGGGGCTGTATGGACGAAGAGCGTTACTCGAGCCCATCGAGT
CACATCTCAAATCCGTGCCGGGATTCTTTGGGTGAATCATTACCATCCAACCTATAATGAAATGCCTTGGGGCGGATACA
AACAAAGTGGAGCGGGTCGTGAGTTAGGCTTGTATGGCATTGAGAGTTACCTTGAGGTCAAGCAAGTGAATATTAACCTG
GATGAAACACCAATTGGTTGGTACTAA

Protein sequence :
MEIYEMYIDGKFTLAKSGTTRDIFDPANGELIARVPESAKEDAILAIKAARKAFDEGEWRKSLALDRGKLLFKLADLIRA
NAKMLAELETRNCGKPLPEAEFDVTDAANCFEFYGGLATKIHGETMSVPANSFSYVVREPIGVCGQIIPWNFPLLMAAWK
LAPALAAGNTVVLKPSELTPITALELFKLIDQCGFPAGVVNLITGPGMGVGEELASNSMVDKVAFTGGSATGRKIMQAAT
GNLKKTSLELGGKNPNIVFADCDLEMAIDGALFGAFANQGEVCSAGSRLLVERSIHKKIVEGMLKKIPNIKLGHGLDAGV
KMGPLVSSAHREKVESYVKLGMEEGAKLLCGGKRPTGSEFAKGHFFEPTIFDEVKSTMRIAREEIFGPVLVVIPFDTEEE
AIRIANDTDYGLSGAVWTKSVTRAHRVTSQIRAGILWVNHYHPTYNEMPWGGYKQSGAGRELGLYGIESYLEVKQVNINL
DETPIGWY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-76 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-71 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-74 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-74 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-74 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-73 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
gbsA YP_001249655.1 glycine betaine aldehyde dehydrogenase VFG0082 Protein 4e-72 41