Gene Information

Name : hemC (LPC_0395)
Accession : YP_001249732.1
Strain : Legionella pneumophila Corby
Genome accession: NC_009494
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 3263626 - 3264591 bp
Length : 966 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGATCTTTACCCAAAGAACATATACCGTCTATTCCATGAGCGCAAAAATTATACGAATCGCAACGAGGCAGAGCCCGCT
TGCACTATGGCAGGCTAATCATGTACGGAAAATGCTTGTAAAGCAATGGCCAAATCTAAGCATTGAATTATTACCCATGA
TAACCTCTGGCGATCGGTTTCTTAAAGATAAATTATTATCCGCAGGAGGAAAAGGGTTATTTGTTAAAGAGTTAGAAGAA
GCATTATTGGATAAAAGAGCGGACTTGGCTGTTCATTCGACCAAAGACATGCCAGCACAACTTCCGGATGGCCTCTTGTT
GGCCGCCATTTGCAAAAGAGATAACCCTTTTGACGCTTTAATAAGTCCCCAATTTAAGAGTCTGGATGCTCTCCCCAAAA
ACGCAATTATCGGTACATCAAGCCTTAGACGTCAATCTCAGCTATTGGCTTACAATCCCAATTTGCAAATCAAAACATTA
AGAGGAAACATCCATACAAGACTCAGCAAACTGGAGTCTGGAGAGTATCAAGCCATTATTCTTGCTGCCGCAGGCTTGGA
AAGAATGGGCTTAGCACATCACATCACCCAACTCATACCCGATGACATTATGCTGCCTACTTGTGCTCAGGGCGCTTTAT
GTATTGAGTGCCGAACGGATGATTTGGAAATCCAAGAGCTGATTCATGGCTTAAATGATCCAATTTCTGCCCTTTGTGTC
CATACCGAGCGACGCGTCAACGCAAAATTAGGAGGCAATTGCCATATACCCTTTGCTGTTTATTGTACCATTACTGAGGA
GAAACGCCTCCTTTTGAGAGCAAAAGTACTTAATATGGATGGTTCTCAAATGATTGATGATGAGCAACAAGGGAAAATTG
CAGAAGCTGAAGTCATTGCAGACAGGTGTACCGAGTCATTAATGACTAAAGGTGCAATGTCCTTATTGAGTACGATACCA
TCATGA

Protein sequence :
MIFTQRTYTVYSMSAKIIRIATRQSPLALWQANHVRKMLVKQWPNLSIELLPMITSGDRFLKDKLLSAGGKGLFVKELEE
ALLDKRADLAVHSTKDMPAQLPDGLLLAAICKRDNPFDALISPQFKSLDALPKNAIIGTSSLRRQSQLLAYNPNLQIKTL
RGNIHTRLSKLESGEYQAIILAAAGLERMGLAHHITQLIPDDIMLPTCAQGALCIECRTDDLEIQELIHGLNDPISALCV
HTERRVNAKLGGNCHIPFAVYCTITEEKRLLLRAKVLNMDGSQMIDDEQQGKIAEAEVIADRCTESLMTKGAMSLLSTIP
S

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-68 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-68 50