Gene Information

Name : cadA (LPC_1846)
Accession : YP_001251124.1
Strain : Legionella pneumophila Corby
Genome accession: NC_009494
Putative virulence/resistance : Resistance
Product : cadmium translocating P-type ATPase CadA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2791141 - 2793276 bp
Length : 2136 bp
Strand : -
Note : -

DNA sequence :
ATGACAGTACCTTTAAATGAAACCAAATTTTTTGTTGCAGGACTTGATTGTCCAGCGGAAGAGCAACTAATCAGAAAGCA
GTTACAGGATATTCCTGAAGTGGAGCAGTTGGATTTTAATTTTATTGCTGAAGAAGTTACTATTCATCACCGGTTGGCTT
CAAGTGAAGAATTGCAAAAACGCATTGAGGCGTTGGGAATGAGTGTTCGAACGCTGGAAAGCACTTTACCTATACCACAA
AGAAAACAATTATCGTTGGATTTTTCCTGGAAAATTATTGGACTAGCAGGTTTTCTTGCCCTATTTTCTGAGCTGGCAGC
TTATTTTTTGGCTACGGAACAATCCATTTGGACTATTCTTCCAGCTTTGTTGGCTATTGGTCTTAGTGGGCCTTCTACCT
TTAAAAAAGGGTGGCTTGCCTTAGGGACTAAAACAATGAATATCAATAGCTTGATGTTCATTGCGATAGCAGGGGCTGTT
CTTATTGGAGAGTGGCCTGAAGCGGCAATGGTGACTGTTTTATTTGCATTGGCCGAACGTATCGAGCGCTACTCCTTAGA
TAAAGCACGTCTTGCGATTCGAAGCTTAATGCAAATTGCCCCTGAGGTGGCTTCAGTGAAACAGGACGATGGTCAATGGC
AAACCTTGGCCATTGAAAAAGTGGTGCCTGGTGCTATTTTTAGAGTAAAACCTGGAGAGCGTATTCCCCTGGATGGCGTG
GTTATTTCAGGTCAGAGCACGGTCAATCAAGCGCCGATTACTGGTGAATCAATGCCAATAACAAAAAAAGTGGGTGATTT
GGTTTTTGCAGGAACATTAAATGAGCACGGCGCGTTTGAAGTGCAGGTCAGTAAAGTGTCAGGCGATACATTGCTTGCTA
AAATTGGTAAAGCGATAGAGCAAGCGCAAGCGGATCGAGCTCCAACACAACGATTTGTTGATCAGTTTTCTAAATATTAT
ACTCCAATTATGGTATTGATGGCTTTTTTTGTTGCATTAATTCCACCTTTAGCATTTGGTTATCCTTTTTATGATTCTCT
TTATAAGTCACTGACTTTATTAGTTATTGCTTGCCCTTGCGCTTTAGTGATTTCAACACCCGTGACTGTTGTAAGTGGCC
TTGCAGCGGCAGCAAAACAAGGGCTTCTTATTAAAGGAGGAAGCTACTTAGAGGTTGGTCATCGACTGAGGTTAATTGCT
TTAGATAAGACAGGTACTTTAACGGAAGGAAAGCCAGTTGTAACTGACTTCATAGCTTGGGATGAAAATCGAACTAAGGA
GAGTTTGTTATTGTTAGCTGCAAGCCTTGATAGTCACTCAGAGCATCCAGTCGCTAATGCCTTAGTACAGTACTGGCAAC
AGGAACAACCTCAAAACGCTTTACTTGAAATTGAGCAATTTTCAGCACTTCCTGGACGAGGAGTAAAGGGATTAGTGGGT
CAAGAACTCTATTTTGTAGGCAATCATCAGTTAGCTGAAGACAATCAGGTATGCAATCATTTTGTCGAACAAGAGCTGAA
GCGCTTGGAGGAAGAAGGTAAAACGACCGTAATATTAAGTAATGCTACGACTGTTTTGGCTATTTTTGCAGTAGCTGATA
CTTTACGTGTTACAAGCCAACAGGCGATTGCACAACTACATGAACGGGGTATAAAAACCGCGATGTTAACGGGAGACAAT
GCGGTAACGGCTCAGGCTATTGCTAAAAAAGTAGGTATTGATGAAGTAAATGCAAATATATTACCTGCGGAAAAACTGCA
AGCGATTAATGGTCTTTTAGATTACTATAATAGCGTTGGGATGGTAGGAGATGGAATTAATGATGCCCCTGCATTGGCAA
AAGCTACCGTGAGTTTTGCGATGGGGAAAGGAACAGATACTGCCTTAGAAACTGCAGACGTTGCCCTAATGAACGACAAT
CTAGCAAGACTCCCCTTTTATATTGATTTAAGTCGTAAGACAGCACGTACTCTTTATCAAAACATCAGTTTATCTATTGC
GATTAAAGGCATTTTCTTTATTTTGGCTCTTGTAGGGTATGCAACGTTATGGATGGCAGTTTTTGCAGACATGGGAGCGA
GTTTAATCGTAGTGGCTAATGGATTGCGATTGTTGTATATGTCCCCAGATGATTAA

Protein sequence :
MTVPLNETKFFVAGLDCPAEEQLIRKQLQDIPEVEQLDFNFIAEEVTIHHRLASSEELQKRIEALGMSVRTLESTLPIPQ
RKQLSLDFSWKIIGLAGFLALFSELAAYFLATEQSIWTILPALLAIGLSGPSTFKKGWLALGTKTMNINSLMFIAIAGAV
LIGEWPEAAMVTVLFALAERIERYSLDKARLAIRSLMQIAPEVASVKQDDGQWQTLAIEKVVPGAIFRVKPGERIPLDGV
VISGQSTVNQAPITGESMPITKKVGDLVFAGTLNEHGAFEVQVSKVSGDTLLAKIGKAIEQAQADRAPTQRFVDQFSKYY
TPIMVLMAFFVALIPPLAFGYPFYDSLYKSLTLLVIACPCALVISTPVTVVSGLAAAAKQGLLIKGGSYLEVGHRLRLIA
LDKTGTLTEGKPVVTDFIAWDENRTKESLLLLAASLDSHSEHPVANALVQYWQQEQPQNALLEIEQFSALPGRGVKGLVG
QELYFVGNHQLAEDNQVCNHFVEQELKRLEEEGKTTVILSNATTVLAIFAVADTLRVTSQQAIAQLHERGIKTAMLTGDN
AVTAQAIAKKVGIDEVNANILPAEKLQAINGLLDYYNSVGMVGDGINDAPALAKATVSFAMGKGTDTALETADVALMNDN
LARLPFYIDLSRKTARTLYQNISLSIAIKGIFFILALVGYATLWMAVFADMGASLIVVANGLRLLYMSPDD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 1e-158 52
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-122 44
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-120 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-120 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_001251124.1 cadmium translocating P-type ATPase CadA BAC0298 Protein 1e-156 52