Gene Information

Name : kdsB (LPC_1373)
Accession : YP_001250673.1
Strain : Legionella pneumophila Corby
Genome accession: NC_009494
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 2232812 - 2233564 bp
Length : 753 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGCCATAATTTTCATGTGATTATACCAGCCAGATATCACTCCAGTCGTTTTCCAGGTAAATTACTTCAAGAAATTAA
CGGCATTACTGTGATTGAACGAGTTTACAGGCAAGCACTTCTGGCAGAACCAAAGTCGGTGATTATTGCCACTGATCATG
ATGAGATAGCTGACCGTGCAATCCAATTTGGAGCGGAGGTTGTAATCACTTCACATACGCACCAAACTGGAACTGATCGA
ATTGCAGAGGTTGTCGCCAAGGGTAGCTTTGCTCCTGATGACGTCATTGTCAATGTGCAAGGTGATGAGCCATTTATCCG
ACCCAAATTAATTCAACAAGTTGCTTGCTCTTTAACGAAGACAAAGGCGCCTGTGTCTACTTTATGCTGGCCTATTAGTA
GCCTTGAAATATTAAATAACCCTAATGTGGTTAAAGTGGTGTGCACTCGAGATAATCACGCTCTTTATTTTTCAAGAAGC
GCAATTCCTTATCACAGAGATAATAAAAGCGCTTATTCCAATACCTTCAGGCATATCGGTTTATATGCTTATCGTGCTGC
CTTTTTACTGGAATTCGTTAGCTGGCCACCCTGTACCTTGGAACAAATAGAGTGTTTGGAGCAATTGCGCATCCTATGGT
CAGGTTTCTCAATCCGGGTTGATGAGGCCTGTGAAGAACCTTTACAGGATATTAATACAAAAGAAGATTTGATTTTGGCT
CAGCAATATTTTCTTGATATTTCCAATATATAA

Protein sequence :
MSHNFHVIIPARYHSSRFPGKLLQEINGITVIERVYRQALLAEPKSVIIATDHDEIADRAIQFGAEVVITSHTHQTGTDR
IAEVVAKGSFAPDDVIVNVQGDEPFIRPKLIQQVACSLTKTKAPVSTLCWPISSLEILNNPNVVKVVCTRDNHALYFSRS
AIPYHRDNKSAYSNTFRHIGLYAYRAAFLLEFVSWPPCTLEQIECLEQLRILWSGFSIRVDEACEEPLQDINTKEDLILA
QQYFLDISNI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 4e-36 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 5e-36 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-36 42