Gene Information

Name : fliP (LPC_1230)
Accession : YP_001250540.1
Strain : Legionella pneumophila Corby
Genome accession: NC_009494
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 2077464 - 2078213 bp
Length : 750 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence :

ATGAAAATTAAAAGTTGGTTACTGATTTTGATATTACTTCTTTTATTACCCGTTGCAGGTCACACAGACCCTTTATCCTT
TCCCGTTGTTACAATGCAACCTGGAACTAATGGTTCGCAATCTTATAGCATCAATCTGCAAATTTTAATTTTTATGACTT
TATTGACCGTATTGCCAGGATTGCTGATGGCAATGACGTCATTTACAAGGATAATTATTGTTCTGTCAATTTTACGGCAG
GCAATAGGGATGGCTCAGACGCCTACCAATCAAATATTAATCGGCATTGCTCTATTTATGACTTATTTTGTTATGTCACC
TGTATTCAACAAAATTAATGAAACAGCAATACAGCCCTATATGAATGAAAGGATTGATTTTTCTCTGGCATTATCCAATG
CACAAAAGCCGCTTCGTCAGTTTATGCTAAATCAAACGAGAAAAAATGATTTATCTTTATTTGAAAAATTTGCTCACAAT
GTACCAAAAAGTTTAGATGAGATTCCTATGAGTGTTCTCATTCCGGCTTTCATTACTAGCGAGTTAAAAACCGCATTTCA
GATAGGCTTTATTCTATTTTTACCTTTTTTAATTATTGATCTTGTTGTGTCCAGTGTTTTGATGGCTATGGGGATGATGA
TGCTTTCACCCTTGATTATTTCATTACCTTTTAAAATCATGTTGTTTGTGATGGTTGATGGATGGACTTTGGTTTTGGGT
TCACTTGCTTCAAGTTTTGCTCTTGCCTAG

Protein sequence :

MKIKSWLLILILLLLLPVAGHTDPLSFPVVTMQPGTNGSQSYSINLQILIFMTLLTVLPGLLMAMTSFTRIIIVLSILRQ
AIGMAQTPTNQILIGIALFMTYFVMSPVFNKINETAIQPYMNERIDFSLALSNAQKPLRQFMLNQTRKNDLSLFEKFAHN
VPKSLDEIPMSVLIPAFITSELKTAFQIGFILFLPFLIIDLVVSSVLMAMGMMMLSPLIISLPFKIMLFVMVDGWTLVLG
SLASSFALA

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
escR	AFO66317.1	putative LEE-encoded type III secretion system factor	Virulence	SESS LEE	Protein	3e-21	43
escR	AFO66400.1	putative LEE-encoded type III secretion system factor	Virulence	SESS LEE	Protein	3e-21	43
hrcR	ABA47279.1	HrcR	Virulence	S-PAI	Protein	6e-20	42
hrcR	AAT96262.1	HrcR	Virulence	S-PAI	Protein	2e-18	42
hrcR	AAT96303.1	HrcR	Virulence	S-PAI	Protein	2e-18	42
hrcR	AAT96343.1	HrcR	Virulence	S-PAI	Protein	2e-18	42
hrcR	NP_791222.3	type III secretion protein HrcR	Virulence	Hrp PAI	Protein	2e-12	41
hrcR	AAP34349.1	HrcR	Virulence	Hrp PAI	Protein	1e-23	41
YPO0270	YP_002345352.1	type III secretion system protein	Virulence	Not named	Protein	1e-22	41
escR	YP_003232138.1	type III secretion system protein	Virulence	LEE	Protein	2e-21	41
escR	YP_003236103.1	T3SS structure protein EscR	Virulence	LEE	Protein	1e-21	41
escR	AAK26700.1	EscR	Virulence	LEE	Protein	1e-21	41
escR	NP_290283.1	type III secretion system protein	Virulence	LEE	Protein	1e-21	41
escR	AAL57527.1	EscR	Virulence	LEE	Protein	1e-21	41
escR	CAC81847.1	EscR protein	Virulence	LEE II	Protein	1e-21	41
escR	CAI43889.1	EscR protein	Virulence	LEE	Protein	1e-21	41
escR	AAC31528.1	L0049	Virulence	LEE	Protein	1e-21	41
ECs4583	NP_312610.1	type III secretion system protein	Virulence	LEE	Protein	4e-21	41
escR	ACU09473.1	type III secretion system protein EscR	Virulence	LEE	Protein	1e-21	41
escR	YP_003223490.1	T3SS structure protein EscR	Virulence	LEE	Protein	2e-21	41

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
fliP	YP_001250540.1	flagellar biosynthesis protein FliP	VFG2016	Protein	1e-96	99
fliP	YP_001250540.1	flagellar biosynthesis protein FliP	VFG1259	Protein	1e-56	62
fliP	YP_001250540.1	flagellar biosynthesis protein FliP	VFG2338	Protein	4e-50	56
fliP	YP_001250540.1	flagellar biosynthesis protein FliP	VFG2494	Protein	5e-50	54
fliP	YP_001250540.1	flagellar biosynthesis protein FliP	VFG2131	Protein	5e-24	43
fliP	YP_001250540.1	flagellar biosynthesis protein FliP	VFG0044	Protein	1e-21	42
fliP	YP_001250540.1	flagellar biosynthesis protein FliP	VFG0827	Protein	6e-22	41