Gene Information

Name : serS (OTBS_1037)
Accession : YP_001248670.1
Strain : Orientia tsutsugamushi Boryong
Genome accession: NC_009488
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1026982 - 1028271 bp
Length : 1290 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGGACATAAAATGGATTAGAGCAAACCCAGATAAACTTGATGAATCACTAAGCAAACGAGGAATTGATTCAGTATC
TAAATCAATAATACATATTGATTCAGAAAAAAGAACATTAATATCTCTAATTCAGAAATTACAGCATGAAAGAAAAGAAA
AATCTAACAGTGTAGCACATATTTATGACAAATCAAGTACTGATTTTGAAGAAATACAAAACGATGTTAAGCTGATCAAT
CAAAAGATAACTGAATTAGAAACTTCATTATTGCATCATGAAAAAAGGTTATCTGAGATTATGGATAACCTTCCTAATTT
AGTAGCTGATGATGTACCCTATGGTACCAATAGTGATATGAATAAAGTGCTTAAAGAATGTGGCACAATTCAAAATATCA
AATTCCCTAAACATCATTATGAAATTGGAAAAAATTTAGGAATGATCGATTTTAATACAGCTACTAAGATGTCAGGCAGT
AGGTTTGTAATTTTAAAACATGATCTTGCGAAACTTGAAAGAGCTTTAATCAATTTTATGATTGATGTACATACTACTGA
GTTTAATTTTTTTGAAGTTTCTCCGCCATGCTTAGTTAAGGACCATGCTATGTATAATGTTGGCCAACTACCTAAATTTG
CTGATGCATCATTTGAGACTACAACTGGATATAGATTGATACCTACTGCAGAAGTGCCATTAACGAATATTTTTGCTAAT
ACTACTTTATTAGAAGAAAAATTACCAATAAGATTGGTAGCGTTTACTCCTTGCTTTAGATCAGAAGTAGGAAGCGCTGG
CAAAGACGTTAAAGGTATGTTGCGAATGCATCAATTTGGTAAAGTAGAACTTTTTACTATCGCTACACCTGAAGAATCAA
ATAGAGAATTTGAGTATCTTACTACTGCTGCTGAAACAATTCTAAAAAAATTATGTTTACCATATAGAGTAGTGTTATTA
TGTAGCGGGGATATAGGATTTGCAGCTCATAAAACATATGATCTTGAAGTGTGGTTACCAGCACAAAATTGTTATAGAGA
AATTTCAAGCTGTTCACATTTTAGTTCTTTTCAAGCTAGAAGATCACTAAGTAAATATAGAGAACTTTGCTCTAAAAAAG
TTAATTTTCTACATACAATCAATGGATCTGGACTTGCTGTTGGCAGAACTATAATTGCTATTCTAGAAAATTATCAAAAT
CCAGATGGATCAGTTACCATTCCTGAAAAGCTTAGGAATTACATGGGAGGGCAGAAACTGATTACACCTTTAACAGAAAC
AGTATTTTGA

Protein sequence :
MLDIKWIRANPDKLDESLSKRGIDSVSKSIIHIDSEKRTLISLIQKLQHERKEKSNSVAHIYDKSSTDFEEIQNDVKLIN
QKITELETSLLHHEKRLSEIMDNLPNLVADDVPYGTNSDMNKVLKECGTIQNIKFPKHHYEIGKNLGMIDFNTATKMSGS
RFVILKHDLAKLERALINFMIDVHTTEFNFFEVSPPCLVKDHAMYNVGQLPKFADASFETTTGYRLIPTAEVPLTNIFAN
TTLLEEKLPIRLVAFTPCFRSEVGSAGKDVKGMLRMHQFGKVELFTIATPEESNREFEYLTTAAETILKKLCLPYRVVLL
CSGDIGFAAHKTYDLEVWLPAQNCYREISSCSHFSSFQARRSLSKYRELCSKKVNFLHTINGSGLAVGRTIIAILENYQN
PDGSVTIPEKLRNYMGGQKLITPLTETVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-93 47