Gene Information

Name : SaurJH9_2445 (SaurJH9_2445)
Accession : YP_001247798.1
Strain : Staphylococcus aureus JH9
Genome accession: NC_009487
Putative virulence/resistance : Virulence
Product : beta-channel forming cytolysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2579329 - 2580294 bp
Length : 966 bp
Strand : +
Note : TIGRFAM: beta-channel forming cytolysin; PFAM: Combined Leucocidin/ASH4 hemolysin

DNA sequence :
ATGAACTTAAAATTAAATAGAAAGAAAGTGATTTCTATGATTAAAAATAAAATATTAACAGCAACTTTAGCAGTTGGTTT
AATAGCCCCTTTAGCCAATCCATTTATAGAAATTTCTAAAGCAGAAAATAAGATAGAAGATATCGGTCAAGGTGCAGAAA
TCATCAAAAGAACACAAGACATTACTAGCAAACGATTAGCTATAACTCAAAACATTCAATTTGATTTTGTAAAAGATAAA
AAATATAACAAAGATGCCCTAGTTGTTAAGATGCAAGGCTTCATCAGCTCTAGAACAACATATTCAGACTTAAAAAAATA
TCCATATATTAAAAGAATGATATGGCCATTTCAATATAATATCAGTTTGAAAACGAAAGACTCTAATGTTGATTTAATCA
ATTATCTTCCTAAAAATAAAATTGATTCAGCAGATGTTAGTCAGAAATTAGGCTATAATATCGGCGGAAACTTCCAATCA
GCGCCATCAATCGGAGGCAGTGGCTCATTCAACTACTCTAAAACAATTAGTTATAATCAAAAAAACTATGTTACTGAAGT
AGAAAGTCAGAACTCTAAAGGTGTTAAATGGGGAGTGAAAGCAAATTCATTTGTTACACCGAATGGTCAAGTATCTGCAT
ATGATCAATACTTATTTGCACAAGACCCAACTGGTCCAGCAGCAAGAGACTATTTCGTCCCAGATAATCAATTACCTCCT
TTAATTCAAAGTGGCTTTAATCCATCATTTATTACAACATTGTCACACGAAAGAGGTAAAGGTGATAAAAGCGAGTTTGA
AATCACTTACGGCAGAAACATGGATGCTACATATGCTTACGTGACAAGACATCGTTTAGCCGTTGATAGAAAACATGATG
CTTTTAAAAACCGAAACGTTACAGTTAAATATGAAGTGAACTGGAAAACACATGAAGTAAAAATTAAAAGCATCACACCT
AAGTAA

Protein sequence :
MNLKLNRKKVISMIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIKRTQDITSKRLAITQNIQFDFVKDK
KYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMIWPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQS
APSIGGSGSFNYSKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARDYFVPDNQLPP
LIQSGFNPSFITTLSHERGKGDKSEFEITYGRNMDATYAYVTRHRLAVDRKHDAFKNRNVTVKYEVNWKTHEVKIKSITP
K

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lukE YP_186708.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
lukE NP_646585.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
lukE NP_372344.1 leukotoxin S-subunit Virulence vSa¥â Protein 4e-106 71
lukE NP_374927.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
lukE YP_001332753.1 leukocidin LukE precursor Virulence vSa¥â Protein 4e-106 71
lukE YP_494460.1 leukotoxin LukE Virulence vSa¥â Protein 4e-106 71
SAKOR_01768 YP_008491956.1 Leukocidin S subunit lukE Virulence vSa¥â Protein 4e-106 71
lukS NP_646196.1 Panton-Valentine leukocidin chain S precursor Virulence ¥ÕSa2 Protein 3e-95 66
lukS-PV YP_494079.1 Panton-Valentine leukocidin, LukS-PV Virulence ¥ÕSa2 Protein 3e-95 66
SAOV_1909 YP_005737354.1 leukocidin chain lukM precursor Virulence ¥ÕSa3 Protein 3e-98 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SaurJH9_2445 YP_001247798.1 beta-channel forming cytolysin VFG1273 Protein 4e-142 100
SaurJH9_2445 YP_001247798.1 beta-channel forming cytolysin VFG1274 Protein 3e-90 68
SaurJH9_2445 YP_001247798.1 beta-channel forming cytolysin VFG1277 Protein 1e-95 66