Gene Information

Name : SaurJH9_1754 (SaurJH9_1754)
Accession : YP_001247120.1
Strain : Staphylococcus aureus JH9
Genome accession: NC_009487
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1859013 - 1860770 bp
Length : 1758 bp
Strand : -
Note : TIGRFAM: pyruvate kinase; PFAM: PEP-utilising enzyme, mobile region; Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta

DNA sequence :
ATGAGAAAAACTAAAATTGTATGTACAATTGGACCAGCTTCAGAATCAGAAGAAATGATTGAGAAATTAATCAATGCTGG
TATGAACGTTGCACGATTAAACTTTTCACATGGTAGTCATGAAGAGCATAAAGGTAGAATTGATACAATTCGTAAAGTAG
CTAAAAGATTAGACAAAATTGTAGCAATTTTATTAGATACGAAAGGTCCAGAAATTCGTACGCATAATATGAAAGACGGT
ATCATTGAACTTGAACGTGGTAACGAAGTTATTGTTAGCATGAATGAAGTTGAAGGAACACCTGAAAAGTTCTCAGTAAC
ATATGAAAACTTAATTAACGATGTTCAAGTAGGTTCATACATTTTACTTGATGATGGCTTAATTGAATTACAAGTTAAAG
ATATTGACCATGCTAAAAAAGAAGTTAAATGTGATATTTTAAACTCTGGTGAGCTTAAAAACAAAAAAGGTGTTAACTTA
CCTGGTGTAAGAGTAAGTTTACCTGGTATTACAGAAAAAGATGCTGAAGATATCCGTTTCGGTATTAAAGAAAATGTTGA
CTTCATTGCAGCAAGTTTCGTACGTCGTCCTAGTGATGTTTTAGAAATTCGTGAAATTTTAGAAGAACAAAAAGCTAACA
TTTCAGTATTCCCTAAAATTGAAAACCAAGAAGGTATTGATAATATTGCGGAAATTCTTGAAGTGTCTGATGGTTTAATG
GTTGCACGTGGTGACATGGGTGTTGAAATTCCACCTGAAAAAGTACCAATGGTTCAAAAAGATTTAATCAGACAATGTAA
CAAATTAGGTAAACCAGTTATTACAGCTACACAAATGTTAGATTCTATGCAACGTAACCCACGTGCTACACGTGCAGAAG
CTAGTGACGTTGCCAACGCAATCTATGATGGTACAGATGCAGTAATGTTATCTGGTGAAACTGCTGCTGGTTTATATCCT
GAAGAAGCTGTTAAAACAATGAGAAATATTGCTGTATCAGCTGAAGCAGCCCAAGATTATAAAAAGTTATTGTCAGATCG
TACTAAATTAGTTGAAACTTCATTAGTGAATGCTATCGGTATTTCGGTTGCACATACAGCTTTAAACTTAAATGTTAAAG
CAATTGTAGCTGCTACTGAAAGTGGTTCAACGGCACGTACTATCTCTAAATATCGTCCACATTCAGACATTATTGCGGTG
ACTCCAAGTGAAGAAACAGCACGTCAATGTTCAATTGTTTGGGGAGTTCAACCTGTAGTTAAAAAAGGACGTAAGAGTAC
AGATGCATTGTTAAACAATGCAGTTGCAACAGCTGTTGAAACTGGTAGAGTATCTAATGGTGATTTAATCATTATTACTG
CTGGTGTACCAACTGGTGAAACTGGAACTACTAATATGATGAAAATCCACCTAGTTGGTGACGAAATTGCTAATGGTCAA
GGTATTGGACGTGGATCAGTTGTTGGTACTACGTTAGTTGCTGAAACTGTTAAAGATTTAGAAGGTAAAGATTTATCTGA
CAAAGTTATCGTTACTAACTCAATCGATGAAACGTTTGTACCTTATGTAGAAAAAGCTTTAGGATTAATTACAGAAGAAA
ATGGTATTACATCACCAAGTGCAATTGTTGGTTTAGAAAAAGGTATTCCAACAGTTGTAGGTGTAGAAAAAGCTGTTAAA
AACATAAGCAATAACATGTTAGTTACGATTGATGCTGCTCAAGGTAAAATCTTTGAAGGATATGCAAACGTACTATAA

Protein sequence :
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDG
IIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL
PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLM
VARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYP
EEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAV
TPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQ
GIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVK
NISNNMLVTIDAAQGKIFEGYANVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-94 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 8e-94 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 8e-94 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-93 49
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 2e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SaurJH9_1754 YP_001247120.1 pyruvate kinase VFG0479 Protein 3e-94 49