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Name : leuS (Tpet_0757) Accession : YP_001244352.1 Strain : Thermotoga petrophila RKU-1 Genome accession: NC_009486 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 767749 - 770223 bp Length : 2475 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAAGGAATACAGACCACAGGAAATAGAGAAAAAATGGCAGGAAGTATGGGAAGAAAAGAAGGTCTTCTATACACCTCA GAGGTCTGAAAAACCCAAGTATTACGCTCTCGTGATGTTTCCGTATCCCTCTGGAACTCTCCACGTAGGGCACGTGAAAA ACTACGTCATAGGTGACATAGTCGCAAGATACAAGAGGATGAGAGGATACAACGTCCTCCACCCGTTTGGATACGACGCA TTCGGACTTCCCGCCGAGAACGCCGCGATCGAAAAGGGAATTCATCCTGAAGAGTGGACGAGGAAGAACATCAACACTAT TCGGGGACAGGTGAAAAAACTCGGTATAAGCTACGACTGGAGCAGAGAAATCGCGACCTGCGACGAGGAGTACTACAAAT GGACCCAGTGGATATTTCTCCAGCTCTACAAGAATGGTTTGGCCTACAAGAAGAAGGCAGCTGTCAACTGGTGTCCCAAG TGTAAAACTGTTCTTGCGAACGAGCAGGTGAAAGACGGAAAATGTGAAAGATGTGGAACCAGCGTTACCATAAGGCACCT CGAACAGTGGTTTTTCAAGATCACGGATTACGCGGAAAGGCTGCTGAACGACCTGGACAAGCTCACAGGATGGCCGGAGC ACGTCAAGACCATGCAGAGAAACTGGATAGGAAAGAGCACCGGTGCGGAAATAGATTTTCCTGTCGAAGGATCGGATACA AAGATCAGGGTCTTCACAACCAGGCCCGACACACTCTGGGGTGTCACTTTCATGGCCCTTGCACCGGAATCCCCTCTTGT CGAAGAGCTCGTTCTTGAGGAGAAAAAAGAAGATCTTCAGGAATTCCTTGAACGTGTAAAGCAGCAGGACAGATTCAGAA GAACCTCTGTCGAGGCCGAAAAAGAAGGGTTCTTCCTGGGAAGGTACGCCATAAACCCCGTGACCGGCGAGAGGATACCG ATCTACGTGGCAAACTACATCCTCATGGAGTATGGAACGGGTGCCATCATGGGAGTTCCTGCCCACGATCAGAGGGACTT TTCCTTCGCTAAAAAGTACGGAATCCCGATAAAGGTTGTGATTAAACCAGCAGACAGAGATCTCGATCCAGAGAAGATGG AAGAAGCCTACGAAGGCGAGGGTATCATGGTGAACTCCGGACCGTTCGATGGAACACCGAGCAGCGAAGGGATAGAAAAA GTCATAAATTGGCTCGAGGAAAAAGGCATTGGAAAGAGGTCGGTCCAGTACAAGTTGAGAGACTGGCTCATATCGAGGCA GAGATACTGGGGCGCTCCAATCCCCATCATCTACTGTGAAAAATGCGGTGTTGTACCCGTTCCAGAAGAGGACCTTCCCG TGAGACTTCCAAAAGACGTGGAATTCCTTCCAACGGGTCAATCTCCTCTTTCTTTCCATGAAGGTTTCAAGAGGACAAAG TGTCCCATCTGTGGTGGAGAAGCCCAGAGAGAAACGGACACCATGGACACTTTCGTTGATTCTTCCTGGTACTTCCTCAG ATACGTGAATCCTCACCTGGAGGACAAACCGTTCGAGCCCGATGATGTGAACTACTGGTTACCGGTGGATCAGTACATCG GAGGGGTGGAACACGCCGTACTGCATTTGCTGTACTCCAGATTCGTAACCAAGGTACTGCACGATCTGGGTTATCTCAAT TTCGACGAACCCTTCACCAACCTCTTCACACAGGGAATGATTTACAAAGACGGTGCCAAGATGTCCAAGTCGAAGGGGAA CGTGGTGTCCCCGGATGAGATGATAGAGAAATACGGGGCGGATACCTTGAGAATGTACATACTCTTCATGGCACCTCCAG AGAAAGACGCCGAATGGAGTGACGCCGGTATCGAAGGTGTTCACAGGTTCATCAAAAGGCTCTGGAACACTTTCTACACG GTTCTTCCGTTTGTGAAAGAAGAAAACACGGAGAATCTTGTGTTGAAAAACTCCACAGAAAAGGAACTCAGAAGAAAGCT TCACAGTATTATCAAGAAGATAACGGAGGATATAGAAGGTGGATTCAAGTTCAACACCGCTATAAGTGGTCTGATGGAAC TCGTGAACCACCTGAGCCAGTACTTGAACAGTGTACCGCAGGAGGAATGGAACAGAAAACTCCTGCGAGAGATAGTAGAA AAACTCACACTCGCTCTTTCACCTTTCGCACCGCACCTTGCAGAGGAGTTCTGGCACGATCTCGGAAACGATAGTCTTGT TGTCCAGCAGGCCTGGCCTTCCTACGATCCAAAAGCGCTCGAAGTGGAGGAAGTCGAAATCGCCATCCAGATAAATGGAA AGGTGAGAGACAAAGTGGTTGTGCCTGTGGATATCTCTGAAGAGGCTCTGAAGAGGATCGTCCTCGAAAGAGAAAGGGTC AAGGAATACGTCGATGGCAAACCAATAAGGAAATTCATTTACGTGAAGGGAAGAATCGTAAATATCGTGGTATGA Protein sequence : MKEYRPQEIEKKWQEVWEEKKVFYTPQRSEKPKYYALVMFPYPSGTLHVGHVKNYVIGDIVARYKRMRGYNVLHPFGYDA FGLPAENAAIEKGIHPEEWTRKNINTIRGQVKKLGISYDWSREIATCDEEYYKWTQWIFLQLYKNGLAYKKKAAVNWCPK CKTVLANEQVKDGKCERCGTSVTIRHLEQWFFKITDYAERLLNDLDKLTGWPEHVKTMQRNWIGKSTGAEIDFPVEGSDT KIRVFTTRPDTLWGVTFMALAPESPLVEELVLEEKKEDLQEFLERVKQQDRFRRTSVEAEKEGFFLGRYAINPVTGERIP IYVANYILMEYGTGAIMGVPAHDQRDFSFAKKYGIPIKVVIKPADRDLDPEKMEEAYEGEGIMVNSGPFDGTPSSEGIEK VINWLEEKGIGKRSVQYKLRDWLISRQRYWGAPIPIIYCEKCGVVPVPEEDLPVRLPKDVEFLPTGQSPLSFHEGFKRTK CPICGGEAQRETDTMDTFVDSSWYFLRYVNPHLEDKPFEPDDVNYWLPVDQYIGGVEHAVLHLLYSRFVTKVLHDLGYLN FDEPFTNLFTQGMIYKDGAKMSKSKGNVVSPDEMIEKYGADTLRMYILFMAPPEKDAEWSDAGIEGVHRFIKRLWNTFYT VLPFVKEENTENLVLKNSTEKELRRKLHSIIKKITEDIEGGFKFNTAISGLMELVNHLSQYLNSVPQEEWNRKLLREIVE KLTLALSPFAPHLAEEFWHDLGNDSLVVQQAWPSYDPKALEVEEVEIAIQINGKVRDKVVVPVDISEEALKRIVLERERV KEYVDGKPIRKFIYVKGRIVNIVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 4e-157 | 44 |
