Gene Information

Name : Tpet_0716 (Tpet_0716)
Accession : YP_001244312.1
Strain : Thermotoga petrophila RKU-1
Genome accession: NC_009486
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 718900 - 720300 bp
Length : 1401 bp
Strand : +
Note : TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta

DNA sequence :
GTGCGAAATACAAAGATCGTGTGTACGGTTGGACCAAGAACAGACAGCTACGAAATGATAGAAAAGATGATAGATCTTGG
AGTGAACGTCTTCAGAATAAACACCTCACACGGCGACTGGAACGAACAGGAACAGAAAATACTCAAAATCAAAGAGTTGA
GAGAGAAAAAGAAAAAACCCGTAGCCGTTCTGATCGATCTTGCGGGTCCGAAGATCAGAACTGGATATCTCGAAAAAGAG
TTTGTAGAATTGAAAGAGGGCCAGATCTTCACTCTCACCACAAAGGAAATACTTGGAAACGAACATATGGTTTCGGTGAA
CCTCAGTTCTCTTCCACAGGACGTGAAAAAAGGAGACACCATTCTGTTGAGCGATGGAGAAATAGTGCTTGAAGTAATTG
AAACGACCGATACAGAAGTGAAAACAGTGGTGAAAGTCGGTGGAAAGATCACACACAGGAGAGGTGTGAACGTACCAACA
GCCGACCTCTCGGTGGAATCCATAACGGACAGAGACAGAGAATTCATAAAGCTCGGAACATTGCACAATGTTGAATTTTT
CGCTCTTTCTTTTGTGAGAAAACCAGAGGACGTGCTCAAGGCAAAAGAAGAGATCAGAAAACACGGAAGCGAAATACCTG
TAATCTCTAAAATAGAAACGAAAAAGGCCCTGGAACGTCTCGAAGAGATAATAAAGGTAAGCGATGGAATCATGGTCGCA
CGCGGTGACCTGGGAGTGGAGATACCCATAGAAGAAGTTCCTATCGTTCAAAAAGAAATCATCAAACTCTCCAAGTACTA
CTCCAAACCAGTTATAGTCGCAACTCAAATACTCGAATCGATGATAGAAAATCCGTTTCCCACGAGGGCAGAGGTCACCG
ACATAGCCAACGCCATCTTTGATGGAGCGGACGCCCTGCTTCTCACAGCGGAAACAGCGGTTGGAAAACATCCCCTGGAA
GCCATAAAAGTGTTGAGCAAAGTAGCAGAAGAGGCCGAAAAAAAGCTGGAATTTTTCAGAACGATAGAATACGATACCAG
CGACATATCTGAGGCCATATCACACGCCTGCTGGCAGCTCTCTGAATCTCTAAACGCGAAGCTGATCATCACACCCACCA
TATCCGGGAGTACCGCCATTCGTGTCTCGAAGTACAACGTTTCTCAACCCATTGTGGCTCTGACACCAGAAGAGAAAACC
TACTACAGACTTTCTCTCGTGAGGAAAGTGATACCCGTTCTCGCCGAAAAGTGCTCTCAGGAGCTGGAGTTCATCGAAAA
AGGATTGAAGAAAGTGGAAGAAATGGGTTTAGCAGAAAAAGGGGATCTGGTGGTTCTCACTTCCGGCGTTCCAGGGAAGG
TGGGAACGACGAACACCATACGGGTGTTGAGGGTGGATTGA

Protein sequence :
MRNTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKELREKKKKPVAVLIDLAGPKIRTGYLEKE
FVELKEGQIFTLTTKEILGNEHMVSVNLSSLPQDVKKGDTILLSDGEIVLEVIETTDTEVKTVVKVGGKITHRRGVNVPT
ADLSVESITDRDREFIKLGTLHNVEFFALSFVRKPEDVLKAKEEIRKHGSEIPVISKIETKKALERLEEIIKVSDGIMVA
RGDLGVEIPIEEVPIVQKEIIKLSKYYSKPVIVATQILESMIENPFPTRAEVTDIANAIFDGADALLLTAETAVGKHPLE
AIKVLSKVAEEAEKKLEFFRTIEYDTSDISEAISHACWQLSESLNAKLIITPTISGSTAIRVSKYNVSQPIVALTPEEKT
YYRLSLVRKVIPVLAEKCSQELEFIEKGLKKVEEMGLAEKGDLVVLTSGVPGKVGTTNTIRVLRVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 6e-69 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-69 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-69 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tpet_0716 YP_001244312.1 pyruvate kinase VFG0479 Protein 2e-69 42