Gene Information

Name : Tpet_0706 (Tpet_0706)
Accession : YP_001244302.1
Strain : Thermotoga petrophila RKU-1
Genome accession: NC_009486
Putative virulence/resistance : Virulence
Product : flagellar protein export ATPase FliI
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.15
Position : 708826 - 710109 bp
Length : 1284 bp
Strand : +
Note : TIGRFAM: ATPase, FliI/YscN family; flagellar protein export ATPase FliI; PFAM: H+-transporting two-sector ATPase, alpha/beta subunit, central region; H+-transporting two-sector ATPase, alpha/beta subunit domain protein; SMART: AAA ATPase

DNA sequence :
TTGAGTGAAGAAGATTTCAATAAATTCAACGGAAGGGTCACAAGAGTGGTAGGGCTCACCGTGGAATCAAAAGGACCAGA
CGCTTTTCTTGGAGAAATGTGTAAAATTTCACTTCAAAACGGCAAGAACGCACTCGCAGAGGTGGTTGGTTTCAGGGAAG
AAAGCGTTATTCTCATGCCTTACGAGGATGTCTCCGGATTGAAGATGAGCTGTGAAGTCATCAGAACTAACAAAGTACTC
GAAGTCGGTGTCAGCAGAAAGATGATCGGAAGGGTGTTCGATGGCCTGGGACGTCCAATAGATGGAAAACCTTTCGTCCC
GGAAGACAGATACCCTCTGACCAACAACCCTCCAAACCCTCTGAAAAGACGAAGAATAAAAGATCCTCTACCAGTGGGCA
TACGATCGATAGATGGCCTCATAACAGTGGGCAAGGGCCAGAGAATAGGGATTTTCGCGGGTAGCGGTGTTGGGAAAAGC
ACACTTCTTGGAATGATTGCACGAAACACAACGGCGGATGTTAACGTGCTGGCTCTCATCGGTGAGCGCGGAAGAGAGGT
CAGAGAATTCATAGAGAGGGACCTTGGAGAAGAGGGGCTGAAGCGGTCCATACTGGTGGTCTCAACCTCCGATCAGCCTG
CCCTTGCCAGAGTGAAATCTCTTCTCACCGCCACCAGTATAGCGGAATTCTTCAGAGATTTGGGATACGATGTTCTTCTG
ATGGTGGACTCTCTCACCAGATGGGCCATGGCCCAGAGAGAAGTGGGACTCGCAGTGGGAGAGCCTCCCACCACCAGGGG
GTATCCACCAAGTGTTTTTGCCGGCCTTCCAAAGATACTCGAAAGGGCAGGAAACTCAGACAAAGGTAGCATAACAGCGA
TTTACACTGTGCTCGTCGAAGCGGACGATTTCAACGAACCCATTTCCGACACTGTCAGATCCATCGTAGATGGACACATA
ATTCTTTCGAGGAGACTTGCCGAATCGAATCACTACCCAGCAGTCGACGTTCTTGCAAGTGTGAGCCGATTGATGAACGA
TATCGTCACTGAAGAACACAGGGAGGCGGCGAACCGCCTCCGATCGCTGATGTCGGCTTATGAATCCGCAAAAGATCTGA
TTGAAATCGGCGCTTACAAGAGCGGAACCAATCCACTCGTTGACAAAGCCGTGGAAATGAAAGACGAGATCGATTCTTTT
CTGAAACAGGGTGTCTTTGAAAAATCTTCATTCGAGGAAACCCTTCAAAAACTTCTGGATCTATACCTGAGATCTCTTGA
CTAA

Protein sequence :
MSEEDFNKFNGRVTRVVGLTVESKGPDAFLGEMCKISLQNGKNALAEVVGFREESVILMPYEDVSGLKMSCEVIRTNKVL
EVGVSRKMIGRVFDGLGRPIDGKPFVPEDRYPLTNNPPNPLKRRRIKDPLPVGIRSIDGLITVGKGQRIGIFAGSGVGKS
TLLGMIARNTTADVNVLALIGERGREVREFIERDLGEEGLKRSILVVSTSDQPALARVKSLLTATSIAEFFRDLGYDVLL
MVDSLTRWAMAQREVGLAVGEPPTTRGYPPSVFAGLPKILERAGNSDKGSITAIYTVLVEADDFNEPISDTVRSIVDGHI
ILSRRLAESNHYPAVDVLASVSRLMNDIVTEEHREAANRLRSLMSAYESAKDLIEIGAYKSGTNPLVDKAVEMKDEIDSF
LKQGVFEKSSFEETLQKLLDLYLRSLD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-103 54
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-98 51
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 2e-99 51
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-98 51
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 3e-91 50
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-91 50
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-91 50
escN AAK26715.1 EscN Virulence LEE Protein 3e-91 50
escN AAL57542.1 EscN Virulence LEE Protein 3e-91 50
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-91 50
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-91 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-99 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-99 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-99 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-99 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-97 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-97 50
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-86 49
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-86 49
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-88 49
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-90 49
escN AAC31513.1 L0034 Virulence LEE Protein 1e-90 49
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-90 49
escN AAC38383.1 EscN Virulence LEE Protein 7e-91 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-90 49
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-91 48
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-87 48
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-87 48
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-87 48
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-88 48
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 8e-88 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 8e-88 48
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-82 47
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-83 47
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 3e-78 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-84 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-84 46
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 8e-80 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 8e-80 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-81 45
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-81 45
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-82 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-86 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 2e-67 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-68 42
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-68 42
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-68 42
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-68 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG0390 Protein 2e-102 54
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG0192 Protein 1e-105 53
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG2144 Protein 2e-102 52
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG1254 Protein 4e-94 51
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG2331 Protein 3e-93 50
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG0048 Protein 6e-100 50
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG0812 Protein 7e-91 49
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG0730 Protein 4e-91 49
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG0515 Protein 5e-88 48
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG2499 Protein 2e-89 48
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG1008 Protein 3e-69 43
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG0555 Protein 5e-69 42
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG2459 Protein 7e-78 42
Tpet_0706 YP_001244302.1 flagellar protein export ATPase FliI VFG1778 Protein 4e-71 41