Gene Information

Name : zntA (BBta_7259)
Accession : YP_001243042.1
Strain : Bradyrhizobium sp. BTAi1
Genome accession: NC_009485
Putative virulence/resistance : Resistance
Product : lead, cadmium, zinc and mercury-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 7624440 - 7626476 bp
Length : 2037 bp
Strand : -
Note : Evidence: Function of homologous gene experimentally demonstrated in an other organism; Localization: 5 : Inner membrane protein; PUBMED: 9405611, 12417201

DNA sequence :
ATGAGCAGCCAGATCGCGGCTGTTGGATATGCCGTTACCGGGTCGGAAGAGGTCGGAGCCAAACACGCTGGTCATGAAGT
GTCCGCTCCCGAGGAAGACACCGGCCGTTTCCACGTCCACGATCACAGCCCCACGAACAAGAGCTGGTGGCAGACCAGCA
AGGCGGATTTGACGATCGCGTCCGGAACCGCGCTCGCAGTCGCCTTCGCATTGGGAAAAGCCATTCCGGCCACCGAACAA
TGGGCATTCCTTCTGGCGATGATGGTCGGCCTGGTCCCGATCGGCAAACGCGCAATTTCCGCAGCGATTGCAGGAACGCC
GTTCTCGATCGAGATGCTGATGACGATTGCCGCGGTCGGCGCGGTCTTCATCGGCGCGACAGAGGAGGCGGCAACGGTCG
TTTTCCTGTTCCTGATCGGCGAAATGCTCGAGGGCGTCGCTGCCAGCCGGGCGCGAGCCAGCATCCAGGACTTGACAAAG
CTTGTTCCAAAGACCGCCCGGCTCGAGGATGATGACGGTCAGGTCCGCGAGGTGGAAGCCGACACGCTATCGGTCGGCGC
CATGATCCAGGTGCGTCCCGGCGACCGCATCCCGGCCGACGGCGTCATCGTATCCGGAGAGAGCGCCATCGACGAAGCGC
CGGTCACAGGCGAAAGCACACCCATCCGCAAGGGGACGGATGCAATGTTGTTTGCCGGTACCGTCAACGGCGACGGATTG
TTACGCGTACGCGTCACCGCCGCTGCAGCGGACAATACGATCGCGCGCGTGGTGCGCCTGGTCGAGGAGGCGCAGGAGTC
TAAGGCGCCGACCGAGCGTTTCATCGACCGCTTCTCGCGCTACTACACGCCCGGCGTGGTAGCGGTCGCGGCTCTGGTGG
CCATCGTCCCGCCGCTGCTATTCGGCGGAGCCTGGAACGGCTGGATCTACAAGGCTCTGGCTATTCTTCTGATTGGCTGT
CCTTGCGCCTTGGTTATCTCTGTGCCTGCGGCGATCGCTGCCAGCCTGTCTGCCGGCGCGCGTCGGGGACTTCTGCTGAA
GGGCGGCGCGGTCCTTGAACAAATCGGCAAGGTCACCGTGGCATGTTTCGACAAGACCGGCACGCTCACCGCCGGCAAGC
CCCAGGTGACGGACATTATCGGCTTCGCACGCAGTGAGGCCGATGTCCTGCGTTTCGCCGCAGCGCTCGAGTCCGGTTCA
AGTCATCCGCTCGCTACTGCGATCTTGGCCAAGGCGGCAGAGCAGAATGTCTGGTTGCCGGCGACCTCCGGCTCGAATGC
GATCGGCGGGAAGGGAATTCGGGCCAGTGTCGAAGGCGCGGAAGTATTCTTGGGATCGCCAAAAGCTGTCGCGGAGATCT
GTACACTGACAAACGAGCAAGACAACAAGATCGCAGCGCTGAACGACGAAGGCAAAACGGTTTCGCTGGTTGCGGTCGAC
GGGCAGATCGCGGGTGCAATCGCGATGCGTGACGAACCCCGCCCTGACGCGAAAAGCGGGCTCAAGCTTTTGACGGATGC
CGGCATCCGGACCGTCATGCTGACGGGTGACAATCGCCGCACGGCGGATGCGATCGGCAAGCAGCTGGGAATAGAAGTTG
AAGCGGAGTTGTTGCCGGAGGACAAGCAGCGCATGGTCGGCAACTTTCAAAAAGCGGGGTGGTCGGTCGCCAAGATCGGC
GACGGTATAAATGATGCGCCAGCGCTGGCGGCCGCCGATGTCGGCATCGCGATGGGCGGCGGTACGGATGTCGCGCTGGA
AACCGCCGACGCCGCCGTGCTGCACGGGCGAGTCGCGGATGTCGCAGCCATGGTCGACCTGTCGAAGCGGACGATGGTCA
ACATCCGGCAGAACATTTTCGTCGCACTCGGACTGAAGGCGGTCTTTCTCATCACCACGGTCGTCGGGCTCACCGGCTTA
TGGCCCGCTATCCTTGCAGACACGGGCGCGACGGTTTTGGTGACAATGAACGCGCTCCGTCTACTTCGCCTTCCGGCAAC
CGGATCTCTTGAACCTAAAGTAGCCAGGAAACTATAA

Protein sequence :
MSSQIAAVGYAVTGSEEVGAKHAGHEVSAPEEDTGRFHVHDHSPTNKSWWQTSKADLTIASGTALAVAFALGKAIPATEQ
WAFLLAMMVGLVPIGKRAISAAIAGTPFSIEMLMTIAAVGAVFIGATEEAATVVFLFLIGEMLEGVAASRARASIQDLTK
LVPKTARLEDDDGQVREVEADTLSVGAMIQVRPGDRIPADGVIVSGESAIDEAPVTGESTPIRKGTDAMLFAGTVNGDGL
LRVRVTAAAADNTIARVVRLVEEAQESKAPTERFIDRFSRYYTPGVVAVAALVAIVPPLLFGGAWNGWIYKALAILLIGC
PCALVISVPAAIAASLSAGARRGLLLKGGAVLEQIGKVTVACFDKTGTLTAGKPQVTDIIGFARSEADVLRFAAALESGS
SHPLATAILAKAAEQNVWLPATSGSNAIGGKGIRASVEGAEVFLGSPKAVAEICTLTNEQDNKIAALNDEGKTVSLVAVD
GQIAGAIAMRDEPRPDAKSGLKLLTDAGIRTVMLTGDNRRTADAIGKQLGIEVEAELLPEDKQRMVGNFQKAGWSVAKIG
DGINDAPALAAADVGIAMGGGTDVALETADAAVLHGRVADVAAMVDLSKRTMVNIRQNIFVALGLKAVFLITTVVGLTGL
WPAILADTGATVLVTMNALRLLRLPATGSLEPKVARKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 5e-95 44
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-94 44
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-94 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
zntA YP_001243042.1 lead, cadmium, zinc and mercury-transporting ATPase BAC0461 Protein 2e-109 51
zntA YP_001243042.1 lead, cadmium, zinc and mercury-transporting ATPase BAC0298 Protein 3e-85 45
zntA YP_001243042.1 lead, cadmium, zinc and mercury-transporting ATPase BAC0092 Protein 2e-74 41